Motif ID: Hoxa5
Z-value: 0.913
Transcription factors associated with Hoxa5:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hoxa5 | ENSMUSG00000038253.6 | Hoxa5 |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 185 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.6 | GO:0006413 | translational initiation(GO:0006413) |
| 0.9 | 6.5 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
| 0.1 | 4.5 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 4.1 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 3.8 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
| 0.6 | 3.6 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
| 0.2 | 2.9 | GO:0016322 | neuron remodeling(GO:0016322) |
| 0.2 | 2.9 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.4 | 2.7 | GO:0044838 | cell quiescence(GO:0044838) |
| 0.2 | 2.7 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
| 0.1 | 2.7 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.9 | 2.6 | GO:0019343 | cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) |
| 0.7 | 2.6 | GO:0070459 | prolactin secretion(GO:0070459) |
| 0.1 | 2.2 | GO:0001913 | T cell mediated cytotoxicity(GO:0001913) |
| 0.1 | 2.1 | GO:0030903 | notochord development(GO:0030903) |
| 0.3 | 1.8 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.4 | 1.7 | GO:0060032 | notochord regression(GO:0060032) |
| 0.5 | 1.6 | GO:1904956 | regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
| 0.1 | 1.6 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 1.6 | GO:0050728 | negative regulation of inflammatory response(GO:0050728) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 82 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.5 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 4.2 | GO:0036464 | cytoplasmic ribonucleoprotein granule(GO:0036464) |
| 0.7 | 2.6 | GO:0097487 | vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487) |
| 0.0 | 2.4 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 2.4 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 2.1 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.1 | 1.8 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.1 | 1.8 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.1 | 1.7 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.1 | 1.2 | GO:0032009 | early phagosome(GO:0032009) |
| 0.1 | 1.2 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 1.2 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.0 | 1.2 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 1.2 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.0 | 1.1 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.0 | 1.1 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.0 | 1.1 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 1.0 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.1 | 1.0 | GO:0097449 | astrocyte projection(GO:0097449) |
| 0.0 | 1.0 | GO:0002080 | acrosomal membrane(GO:0002080) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 116 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 6.5 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.1 | 5.7 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 4.3 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 4.2 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.3 | 4.0 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.3 | 3.1 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.2 | 3.0 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 2.9 | GO:0008026 | ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035) |
| 0.9 | 2.6 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.2 | 2.6 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
| 0.8 | 2.4 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.2 | 2.4 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.7 | 2.2 | GO:0098809 | nitrite reductase activity(GO:0098809) |
| 0.2 | 2.2 | GO:0031404 | chloride ion binding(GO:0031404) |
| 0.0 | 2.1 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.1 | 1.8 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 1.8 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.4 | 1.5 | GO:0046923 | ER retention sequence binding(GO:0046923) |
| 0.1 | 1.5 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.1 | 1.5 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 31 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.0 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.2 | 2.8 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.0 | 2.8 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 2.6 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 2.2 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.0 | 2.0 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 2.0 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 1.9 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 1.7 | PID_ARF6_PATHWAY | Arf6 signaling events |
| 0.0 | 1.4 | PID_LYSOPHOSPHOLIPID_PATHWAY | LPA receptor mediated events |
| 0.0 | 1.2 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.1 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.1 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 0.8 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 0.6 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.6 | ST_INTEGRIN_SIGNALING_PATHWAY | Integrin Signaling Pathway |
| 0.0 | 0.6 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.0 | 0.6 | PID_E2F_PATHWAY | E2F transcription factor network |
| 0.0 | 0.5 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 0.5 | PID_ATM_PATHWAY | ATM pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 47 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 5.9 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.2 | 2.8 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.1 | 2.6 | REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING | Genes involved in SHC1 events in EGFR signaling |
| 0.1 | 2.3 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.1 | 2.3 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
| 0.0 | 2.3 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 2.3 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.1 | 1.8 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 1.6 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 1.4 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 1.3 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 1.2 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
| 0.1 | 1.2 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 1.2 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.1 | 1.0 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.0 | 1.0 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.9 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 0.8 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.0 | 0.8 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.8 | REACTOME_INWARDLY_RECTIFYING_K_CHANNELS | Genes involved in Inwardly rectifying K+ channels |
