Motif ID: Hoxa9_Hoxb9
Z-value: 0.446
Transcription factors associated with Hoxa9_Hoxb9:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hoxa9 | ENSMUSG00000038227.9 | Hoxa9 |
| Hoxb9 | ENSMUSG00000020875.8 | Hoxb9 |
Top targets:
Showing 1 to 20 of 111 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 36 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.9 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.7 | 2.1 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
| 0.1 | 1.7 | GO:0032098 | regulation of appetite(GO:0032098) |
| 0.3 | 1.6 | GO:0006538 | glutamate catabolic process(GO:0006538) |
| 0.1 | 1.5 | GO:0032291 | central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) |
| 0.0 | 1.4 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
| 0.0 | 1.3 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.1 | 0.9 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
| 0.1 | 0.7 | GO:0042636 | negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279) |
| 0.1 | 0.7 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.0 | 0.7 | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) |
| 0.0 | 0.6 | GO:0008299 | isoprenoid biosynthetic process(GO:0008299) |
| 0.1 | 0.5 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.1 | 0.5 | GO:0021785 | branchiomotor neuron axon guidance(GO:0021785) |
| 0.1 | 0.5 | GO:0019896 | axonal transport of mitochondrion(GO:0019896) |
| 0.0 | 0.5 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 0.0 | 0.5 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.1 | 0.4 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
| 0.1 | 0.4 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
| 0.1 | 0.4 | GO:0032264 | IMP salvage(GO:0032264) |
Gene overrepresentation in cellular_component category:
Showing 1 to 16 of 16 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.2 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 1.7 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 1.2 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 1.1 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 0.9 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.0 | 0.9 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.2 | 0.7 | GO:0043512 | inhibin A complex(GO:0043512) |
| 0.1 | 0.5 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.0 | 0.5 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 0.5 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.0 | 0.4 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.1 | 0.3 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.0 | 0.3 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.2 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.0 | 0.1 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.0 | 0.0 | GO:0097447 | dendritic tree(GO:0097447) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 32 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 2.1 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.1 | 2.1 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.2 | 1.6 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.0 | 0.9 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.1 | 0.7 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.1 | 0.6 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.0 | 0.5 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 0.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 0.5 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.1 | 0.4 | GO:0032896 | palmitoyl-CoA 9-desaturase activity(GO:0032896) |
| 0.1 | 0.4 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.1 | 0.4 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.0 | 0.4 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 0.0 | 0.4 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 0.4 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.0 | 0.3 | GO:0002135 | CTP binding(GO:0002135) |
| 0.0 | 0.3 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.0 | 0.3 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.0 | 0.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
Gene overrepresentation in C2:CP category:
Showing 1 to 8 of 8 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
| 0.0 | 1.5 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 1.1 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.1 | 0.8 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
| 0.0 | 0.7 | PID_ALK1_PATHWAY | ALK1 signaling events |
| 0.1 | 0.4 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
| 0.0 | 0.3 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.2 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 13 of 13 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.6 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.0 | 1.7 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.1 | 1.6 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 1.6 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 1.5 | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.0 | 0.9 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 0.8 | REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.2 | 0.7 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 0.6 | REACTOME_G_PROTEIN_ACTIVATION | Genes involved in G-protein activation |
| 0.0 | 0.5 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 0.4 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.4 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 0.2 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
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