Motif ID: Hoxb1
Z-value: 0.610
Transcription factors associated with Hoxb1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hoxb1 | ENSMUSG00000018973.2 | Hoxb1 |
Top targets:
Showing 1 to 20 of 70 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 38 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 5.1 | GO:0060032 | notochord regression(GO:0060032) |
| 0.1 | 3.1 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
| 0.0 | 2.7 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
| 0.3 | 2.1 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.0 | 2.0 | GO:0021954 | central nervous system neuron development(GO:0021954) |
| 0.1 | 1.9 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.0 | 1.7 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.2 | 1.6 | GO:0033563 | dorsal/ventral axon guidance(GO:0033563) |
| 0.0 | 1.6 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.2 | 1.5 | GO:1903847 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
| 0.0 | 1.5 | GO:0007628 | adult walking behavior(GO:0007628) |
| 0.1 | 1.4 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
| 0.0 | 1.2 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
| 0.0 | 1.2 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
| 0.1 | 1.0 | GO:1900121 | negative regulation of receptor binding(GO:1900121) |
| 0.1 | 0.8 | GO:0032693 | negative regulation of interleukin-10 production(GO:0032693) |
| 0.2 | 0.7 | GO:1990927 | negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927) |
| 0.1 | 0.7 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.1 | 0.6 | GO:0097374 | sensory neuron axon guidance(GO:0097374) |
| 0.1 | 0.6 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
Gene overrepresentation in cellular_component category:
Showing 1 to 11 of 11 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 5.1 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.1 | 1.9 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.1 | 1.7 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.1 | 1.3 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.1 | 1.2 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 0.7 | GO:0032009 | early phagosome(GO:0032009) |
| 0.2 | 0.5 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.1 | 0.4 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.0 | 0.3 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 0.2 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
| 0.0 | 0.2 | GO:0030061 | mitochondrial crista(GO:0030061) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 27 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.0 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.2 | 3.1 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.5 | 2.7 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.0 | 2.0 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 1.9 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.2 | 1.6 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.0 | 1.5 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.1 | 1.4 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.3 | 1.3 | GO:0008802 | betaine-aldehyde dehydrogenase activity(GO:0008802) |
| 0.1 | 1.0 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.0 | 1.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 0.8 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.0 | 0.7 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.2 | 0.6 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 0.0 | 0.6 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 0.5 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
| 0.0 | 0.5 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 0.5 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.1 | 0.4 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
| 0.1 | 0.3 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
Gene overrepresentation in C2:CP category:
Showing 1 to 9 of 9 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.1 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 3.1 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 1.6 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 1.5 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.0 | 1.4 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 1.0 | PID_BMP_PATHWAY | BMP receptor signaling |
| 0.0 | 0.6 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.6 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.3 | PID_IL5_PATHWAY | IL5-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 7 of 7 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.1 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 2.7 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 2.5 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 1.9 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 0.6 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 0.5 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.2 | REACTOME_STEROID_HORMONES | Genes involved in Steroid hormones |
