Motif ID: Hoxb3
Z-value: 1.283
Transcription factors associated with Hoxb3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hoxb3 | ENSMUSG00000048763.5 | Hoxb3 |
Top targets:
Showing 1 to 20 of 130 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 59 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.8 | 27.1 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.6 | 19.8 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 1.2 | 8.7 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.1 | 8.6 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 1.1 | 5.5 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
| 1.3 | 5.3 | GO:0032788 | saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789) |
| 0.5 | 5.1 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.2 | 5.0 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.4 | 3.6 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.0 | 3.3 | GO:0007568 | aging(GO:0007568) |
| 0.6 | 3.2 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.5 | 2.8 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
| 0.5 | 2.3 | GO:0002677 | negative regulation of chronic inflammatory response(GO:0002677) |
| 0.1 | 2.2 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 2.1 | GO:0045580 | regulation of T cell differentiation(GO:0045580) |
| 0.1 | 2.0 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 0.3 | 1.9 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.2 | 1.8 | GO:0080184 | response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184) |
| 0.1 | 1.8 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.2 | 1.7 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 24 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 33.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 25.1 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.2 | 4.6 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 4.0 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.1 | 3.5 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 3.1 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.1 | 2.5 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 2.3 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.5 | 1.8 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.0 | 1.7 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 1.6 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.1 | 1.4 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.0 | 1.4 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.2 | 1.2 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.0 | 1.1 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 1.0 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 0.7 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.0 | 0.7 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.0 | 0.6 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.4 | GO:0035861 | site of double-strand break(GO:0035861) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 52 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 27.1 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 1.7 | 19.2 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.8 | 8.7 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
| 0.3 | 5.3 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 1.0 | 5.1 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 0.4 | 5.0 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.0 | 4.0 | GO:0005525 | GTP binding(GO:0005525) |
| 0.4 | 3.6 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 1.2 | 3.5 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 1.1 | 3.2 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.1 | 3.1 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.5 | 2.3 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
| 0.1 | 2.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.1 | 2.2 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.0 | 2.0 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.5 | 1.8 | GO:0031720 | haptoglobin binding(GO:0031720) |
| 0.0 | 1.8 | GO:0008026 | ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035) |
| 0.2 | 1.7 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.1 | 1.6 | GO:0045125 | bioactive lipid receptor activity(GO:0045125) |
| 0.1 | 1.5 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
Gene overrepresentation in C2:CP category:
Showing 1 to 7 of 7 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.5 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 5.1 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 2.2 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.1 | 1.4 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 1.1 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
| 0.0 | 0.2 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.2 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 16 of 16 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 25.6 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.2 | 8.5 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.2 | 5.1 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.2 | 3.2 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 2.9 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 2.4 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 2.3 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.2 | 1.7 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.0 | 1.1 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.1 | 0.7 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 0.7 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 0.7 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 0.6 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.0 | 0.6 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
| 0.0 | 0.4 | REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.0 | 0.2 | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
