Motif ID: Junb_Jund

Z-value: 1.551

Transcription factors associated with Junb_Jund:

Gene SymbolEntrez IDGene Name
Junb ENSMUSG00000052837.5 Junb
Jund ENSMUSG00000071076.5 Jund

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Junbmm10_v2_chr8_-_84978709_849787480.381.4e-02Click!
Jundmm10_v2_chr8_+_70697739_706977390.144.0e-01Click!


Activity profile for motif Junb_Jund.

activity profile for motif Junb_Jund


Sorted Z-values histogram for motif Junb_Jund

Sorted Z-values for motif Junb_Jund



Network of associatons between targets according to the STRING database.



First level regulatory network of Junb_Jund

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_142095266 13.622 ENSMUST00000039926.3
 Dusp8
dual specificity phosphatase 8
chr13_-_54688264 12.334 ENSMUST00000150626.1
ENSMUST00000134177.1
 Rnf44

ring finger protein 44

chr2_+_155276297 11.298 ENSMUST00000029128.3
 Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr6_+_54681687 10.591 ENSMUST00000046276.6
 2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr13_-_54688246 9.350 ENSMUST00000122935.1
ENSMUST00000128257.1
 Rnf44

ring finger protein 44

chr14_+_66344369 7.987 ENSMUST00000118426.1
ENSMUST00000121955.1
ENSMUST00000120229.1
ENSMUST00000134440.1
 Stmn4



stathmin-like 4



chr14_+_66344296 7.605 ENSMUST00000152093.1
ENSMUST00000074523.6
 Stmn4

stathmin-like 4

chr6_-_23248264 7.513 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr1_-_79440039 6.407 ENSMUST00000049972.4
 Scg2
secretogranin II
chr9_-_98032983 6.246 ENSMUST00000162295.1
 Clstn2
calsyntenin 2
chr4_+_32238950 6.157 ENSMUST00000037416.6
 Bach2
BTB and CNC homology 2
chr7_+_139248477 6.093 ENSMUST00000093993.3
ENSMUST00000172136.1
 Pwwp2b

PWWP domain containing 2B

chr6_-_124464772 6.049 ENSMUST00000008297.4
 Clstn3
calsyntenin 3
chr17_-_46487641 5.937 ENSMUST00000047034.8
 Ttbk1
tau tubulin kinase 1
chr13_-_54688184 5.915 ENSMUST00000150806.1
ENSMUST00000125927.1
 Rnf44

ring finger protein 44

chr4_+_21931291 5.893 ENSMUST00000029908.7
 Faxc
failed axon connections homolog (Drosophila)
chr9_+_40269273 5.562 ENSMUST00000176185.1
 Scn3b
sodium channel, voltage-gated, type III, beta
chr17_-_26508463 5.522 ENSMUST00000025025.6
 Dusp1
dual specificity phosphatase 1
chr2_+_118663235 5.487 ENSMUST00000099557.3
 Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr9_+_40269202 5.449 ENSMUST00000114956.3
ENSMUST00000049941.5
 Scn3b

sodium channel, voltage-gated, type III, beta


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 311 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 31.6 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.3 27.4 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
1.3 15.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.3 14.8 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.4 12.6 GO:0006198 cAMP catabolic process(GO:0006198)
1.3 12.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.2 11.0 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.6 10.7 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.1 10.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.1 9.6 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
3.0 8.9 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.5 8.8 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
1.4 8.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 8.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 7.5 GO:0008089 anterograde axonal transport(GO:0008089)
1.1 7.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.4 7.4 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 6.8 GO:0010508 positive regulation of autophagy(GO:0010508)
1.3 6.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.5 6.0 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 144 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 48.4 GO:0014069 postsynaptic density(GO:0014069)
0.0 29.0 GO:0005794 Golgi apparatus(GO:0005794)
0.1 18.6 GO:0099503 secretory vesicle(GO:0099503)
0.3 13.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.5 12.5 GO:0031430 M band(GO:0031430)
0.8 11.3 GO:0044754 autolysosome(GO:0044754)
0.2 11.3 GO:0005776 autophagosome(GO:0005776)
0.7 11.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 10.9 GO:0044295 axonal growth cone(GO:0044295)
0.2 8.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 8.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 8.9 GO:0001650 fibrillar center(GO:0001650)
0.1 8.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 7.8 GO:0043204 perikaryon(GO:0043204)
0.0 7.2 GO:0005769 early endosome(GO:0005769)
0.5 5.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.1 5.4 GO:0032437 cuticular plate(GO:0032437)
0.1 5.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 5.2 GO:0005923 bicellular tight junction(GO:0005923)
0.2 5.1 GO:0030673 axolemma(GO:0030673)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 192 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 43.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 35.9 GO:0015631 tubulin binding(GO:0015631)
0.0 15.7 GO:0005509 calcium ion binding(GO:0005509)
1.6 12.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 12.5 GO:0030507 spectrin binding(GO:0030507)
1.2 11.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.6 11.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.8 9.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 9.4 GO:0030276 clathrin binding(GO:0030276)
0.1 9.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.6 8.9 GO:0045499 chemorepellent activity(GO:0045499)
1.5 8.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4 7.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.4 7.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 7.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 7.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 6.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.3 6.5 GO:0031489 myosin V binding(GO:0031489)
0.6 6.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 6.0 GO:0042056 chemoattractant activity(GO:0042056)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 51 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 15.7 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.2 9.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 9.4 PID_NFAT_3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2 9.0 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.2 8.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.2 8.1 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 7.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 6.0 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 5.9 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.2 5.2 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.1 4.5 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.2 4.0 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.7 PID_LKB1_PATHWAY LKB1 signaling events
0.1 3.2 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 2.9 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 2.7 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 2.3 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 2.3 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.2 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.0 PID_ATF2_PATHWAY ATF-2 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 18.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.9 17.8 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 7.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 6.2 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 5.3 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 5.3 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.3 5.0 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.2 4.5 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 4.5 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.2 4.2 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.6 4.1 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 4.1 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
1.0 3.9 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 3.9 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 3.8 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 3.8 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.2 3.7 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.3 3.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 3.3 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.1 3.2 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1