Motif ID: Lhx3
Z-value: 0.523

Transcription factors associated with Lhx3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Lhx3 | ENSMUSG00000026934.9 | Lhx3 |
Top targets:
Showing 1 to 20 of 89 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 37 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.5 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.0 | 2.5 | GO:0009063 | cellular amino acid catabolic process(GO:0009063) |
0.2 | 1.7 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
0.0 | 1.5 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
0.0 | 1.5 | GO:0042742 | defense response to bacterium(GO:0042742) |
0.2 | 1.4 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.0 | 1.3 | GO:0021549 | cerebellum development(GO:0021549) |
0.0 | 1.1 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.3 | 1.0 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
0.0 | 1.0 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.3 | 0.9 | GO:2000564 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
0.2 | 0.9 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
0.0 | 0.9 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.1 | 0.8 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.1 | 0.8 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.0 | 0.8 | GO:0046677 | response to antibiotic(GO:0046677) |
0.1 | 0.7 | GO:0035610 | protein side chain deglutamylation(GO:0035610) |
0.1 | 0.7 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
0.1 | 0.6 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.1 | 0.5 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
Gene overrepresentation in cellular_component category:
Showing 1 to 18 of 18 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 3.6 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
0.2 | 2.5 | GO:0042581 | specific granule(GO:0042581) |
0.1 | 1.7 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 1.1 | GO:0034707 | chloride channel complex(GO:0034707) |
0.1 | 1.0 | GO:0042629 | mast cell granule(GO:0042629) |
0.1 | 0.9 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 0.9 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.8 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 0.6 | GO:0071564 | npBAF complex(GO:0071564) |
0.0 | 0.6 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.5 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.1 | 0.4 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.1 | 0.4 | GO:0005955 | calcineurin complex(GO:0005955) |
0.0 | 0.3 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 0.2 | GO:0071439 | clathrin complex(GO:0071439) |
0.0 | 0.2 | GO:0045275 | respiratory chain complex III(GO:0045275) |
0.0 | 0.2 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
0.0 | 0.1 | GO:0097637 | intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 28 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 3.6 | GO:0031721 | haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721) |
0.7 | 3.6 | GO:0019770 | IgG receptor activity(GO:0019770) |
0.8 | 2.5 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
0.0 | 2.2 | GO:0008083 | growth factor activity(GO:0008083) |
0.4 | 1.7 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
0.2 | 1.4 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.0 | 1.2 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.1 | 1.1 | GO:0050811 | GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811) |
0.1 | 1.0 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
0.0 | 1.0 | GO:0005518 | collagen binding(GO:0005518) |
0.1 | 0.9 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.0 | 0.9 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.8 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.7 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 0.6 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 0.5 | GO:0004601 | peroxidase activity(GO:0004601) |
0.0 | 0.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.1 | 0.4 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
0.0 | 0.4 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.0 | 0.4 | GO:0002162 | dystroglycan binding(GO:0002162) |
Gene overrepresentation in C2:CP category:
Showing 1 to 4 of 4 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.2 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.1 | 1.7 | PID_IL5_PATHWAY | IL5-mediated signaling events |
0.0 | 0.8 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.0 | 0.4 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 9 of 9 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.2 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
0.0 | 2.1 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.1 | 1.7 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
0.0 | 1.4 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 1.2 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.1 | 1.0 | REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
0.0 | 1.0 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ | Genes involved in Response to elevated platelet cytosolic Ca2+ |
0.0 | 0.4 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
0.0 | 0.2 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |