Motif ID: Meox2

Z-value: 0.731


Transcription factors associated with Meox2:

Gene SymbolEntrez IDGene Name
Meox2 ENSMUSG00000036144.5 Meox2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meox2mm10_v2_chr12_+_37108533_371085460.408.6e-03Click!


Activity profile for motif Meox2.

activity profile for motif Meox2


Sorted Z-values histogram for motif Meox2

Sorted Z-values for motif Meox2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meox2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 142 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_25980039 4.597 ENSMUST00000173155.1
 Duxbl1
double homeobox B-like 1
chr14_+_26119811 4.492 ENSMUST00000173617.1
 Duxbl2
doubl homeobox B-like 2
chr16_+_42907563 4.001 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr14_+_26259109 3.743 ENSMUST00000174494.1
 Duxbl3
double homeobox B-like 3
chr14_+_25979401 2.025 ENSMUST00000173580.1
 Duxbl1
double homeobox B-like 1
chr10_-_116972609 1.696 ENSMUST00000092165.4
 Gm10271
predicted gene 10271
chr14_+_26119173 1.572 ENSMUST00000174564.1
 Duxbl2
doubl homeobox B-like 2
chr14_+_26258786 1.572 ENSMUST00000172517.1
 Duxbl3
double homeobox B-like 3
chr5_-_62766153 1.510 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr8_-_46294592 1.425 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr3_+_107291215 1.420 ENSMUST00000029502.7
 Slc16a4
solute carrier family 16 (monocarboxylic acid transporters), member 4
chr2_+_120629113 1.386 ENSMUST00000150912.1
ENSMUST00000180041.1
 Stard9

START domain containing 9

chr19_-_9559204 1.351 ENSMUST00000090527.3
 Stxbp3b
syntaxin-binding protein 3B
chr9_+_21927471 1.273 ENSMUST00000170304.1
ENSMUST00000006403.6
 Ccdc159

coiled-coil domain containing 159

chr3_-_54714353 1.263 ENSMUST00000178832.1
 Gm21958
predicted gene, 21958
chr3_+_66219909 1.231 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chr10_-_88683021 1.218 ENSMUST00000004473.8
 Spic
Spi-C transcription factor (Spi-1/PU.1 related)
chr8_+_66386292 1.166 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr3_+_127553462 1.163 ENSMUST00000043108.4
 4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr13_-_77131276 1.121 ENSMUST00000159300.1
 Ankrd32
ankyrin repeat domain 32

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.6 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.1 4.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.4 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.0 1.4 GO:0051225 spindle assembly(GO:0051225)
0.0 1.4 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.2 1.2 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 1.2 GO:0001824 blastocyst development(GO:0001824)
0.1 1.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 1.1 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.3 1.0 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.1 1.0 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 0.8 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.1 0.8 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.2 0.7 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 0.7 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 0.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.7 GO:0051775 response to redox state(GO:0051775)
0.0 0.7 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 0.6 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.1 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 1.0 GO:0070469 respiratory chain(GO:0070469)
0.0 0.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.6 GO:0005844 polysome(GO:0005844)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.5 GO:0042588 zymogen granule(GO:0042588)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.2 1.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.2 GO:0042287 MHC protein binding(GO:0042287)
0.3 1.1 GO:0050436 microfibril binding(GO:0050436)
0.0 1.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.8 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.6 GO:0000150 recombinase activity(GO:0000150)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 0.5 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0005507 copper ion binding(GO:0005507)
0.0 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)

Gene overrepresentation in C2:CP category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.2 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.0 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.4 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis