Motif ID: Myf6

Z-value: 1.543


Transcription factors associated with Myf6:

Gene SymbolEntrez IDGene Name
Myf6 ENSMUSG00000035923.3 Myf6



Activity profile for motif Myf6.

activity profile for motif Myf6


Sorted Z-values histogram for motif Myf6

Sorted Z-values for motif Myf6



Network of associatons between targets according to the STRING database.



First level regulatory network of Myf6

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_91269759 14.205 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr8_+_125995102 9.554 ENSMUST00000046765.8
 Kcnk1
potassium channel, subfamily K, member 1
chr6_+_6863769 9.515 ENSMUST00000031768.6
 Dlx6
distal-less homeobox 6
chr2_-_71546745 8.581 ENSMUST00000024159.6
 Dlx2
distal-less homeobox 2
chr6_+_6863269 8.208 ENSMUST00000160937.2
ENSMUST00000171311.1
 Dlx6

distal-less homeobox 6

chr4_-_64046925 7.728 ENSMUST00000107377.3
 Tnc
tenascin C
chr3_+_118433797 7.663 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
 Gm26871



predicted gene, 26871



chr11_+_50602072 7.075 ENSMUST00000040523.8
 Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr16_+_41532999 6.199 ENSMUST00000099761.3
 Lsamp
limbic system-associated membrane protein
chr15_-_66812593 5.699 ENSMUST00000100572.3
 Sla
src-like adaptor
chr3_+_89520152 5.653 ENSMUST00000000811.7
 Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr2_-_36104060 5.251 ENSMUST00000112961.3
ENSMUST00000112966.3
 Lhx6

LIM homeobox protein 6

chr9_+_27790947 5.093 ENSMUST00000115243.2
 Opcml
opioid binding protein/cell adhesion molecule-like
chr11_+_115163333 4.991 ENSMUST00000021077.3
 Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chrX_+_73503074 4.895 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
 Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr13_+_29014399 4.865 ENSMUST00000146336.1
ENSMUST00000130109.1
 A330102I10Rik

RIKEN cDNA A330102I10 gene

chr12_-_119238794 4.566 ENSMUST00000026360.8
 Itgb8
integrin beta 8
chr10_-_8518801 4.346 ENSMUST00000061601.7
 Ust
uronyl-2-sulfotransferase
chr4_+_119814495 4.218 ENSMUST00000106307.2
 Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr7_+_130936172 4.179 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 251 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 14.9 GO:0006813 potassium ion transport(GO:0006813)
0.1 12.5 GO:0060021 palate development(GO:0060021)
0.1 11.9 GO:0048709 oligodendrocyte differentiation(GO:0048709)
1.3 11.5 GO:1900034 regulation of cellular response to heat(GO:1900034)
1.5 9.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
2.9 8.6 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.3 8.6 GO:0035641 locomotory exploration behavior(GO:0035641)
2.1 8.3 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.7 7.5 GO:0042572 retinol metabolic process(GO:0042572)
0.4 6.3 GO:0030574 collagen catabolic process(GO:0030574)
0.4 6.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 5.9 GO:0030279 negative regulation of ossification(GO:0030279)
0.9 5.4 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 5.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
1.1 5.3 GO:1990034 calcium ion export from cell(GO:1990034)
0.9 5.3 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
1.0 5.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 5.1 GO:0030032 lamellipodium assembly(GO:0030032)
1.7 5.0 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.6 5.0 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 117 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 16.5 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 10.3 GO:0031594 neuromuscular junction(GO:0031594)
2.4 9.6 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 8.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 8.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 8.2 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.5 7.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 7.6 GO:0008021 synaptic vesicle(GO:0008021)
0.2 7.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 5.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.1 5.6 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 5.0 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.4 4.8 GO:0032426 stereocilium tip(GO:0032426)
0.0 4.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 4.5 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
1.0 4.1 GO:0044307 dendritic branch(GO:0044307)
1.0 4.0 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.3 4.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 4.0 GO:0031526 brush border membrane(GO:0031526)
0.0 3.9 GO:0005905 clathrin-coated pit(GO:0005905)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 176 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.1 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
1.6 11.5 GO:0099609 microtubule lateral binding(GO:0099609)
1.0 10.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 8.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
1.3 7.7 GO:0045545 syndecan binding(GO:0045545)
1.1 7.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 7.3 GO:0005179 hormone activity(GO:0005179)
0.1 6.3 GO:0016247 channel regulator activity(GO:0016247)
0.0 6.3 GO:0008270 zinc ion binding(GO:0008270)
0.4 5.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.9 5.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.7 5.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.5 5.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.4 5.0 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 4.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
1.2 4.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.7 4.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 4.8 GO:0005504 fatty acid binding(GO:0005504)
1.5 4.6 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 4.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 16.7 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 16.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 11.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.3 10.4 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.5 9.7 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 8.7 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 8.0 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 7.6 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 7.2 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.2 6.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 5.3 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 5.3 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.3 4.2 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.2 3.6 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.6 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 3.5 PID_EPO_PATHWAY EPO signaling pathway
0.2 3.2 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.2 3.1 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.4 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 2.2 PID_IL1_PATHWAY IL1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 14.8 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.3 13.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.2 12.8 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
1.5 10.7 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 10.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.3 7.5 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 6.4 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 6.2 REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1 5.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.2 5.1 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.4 4.9 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 4.7 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 4.3 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 4.2 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.4 4.1 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.2 4.0 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 3.9 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 3.7 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 3.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.2 3.0 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation