Motif ID: Myod1

Z-value: 0.495


Transcription factors associated with Myod1:

Gene SymbolEntrez IDGene Name
Myod1 ENSMUSG00000009471.3 Myod1



Activity profile for motif Myod1.

activity profile for motif Myod1


Sorted Z-values histogram for motif Myod1

Sorted Z-values for motif Myod1



Network of associatons between targets according to the STRING database.



First level regulatory network of Myod1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_8518801 2.075 ENSMUST00000061601.7
Ust
uronyl-2-sulfotransferase
chr7_+_96210107 1.920 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr12_-_34528844 1.776 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr7_+_122289297 1.457 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr5_+_134986191 1.372 ENSMUST00000094245.2
Cldn3
claudin 3
chr11_-_107915041 1.322 ENSMUST00000039071.2
Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr5_+_105415738 1.223 ENSMUST00000112707.1
Lrrc8b
leucine rich repeat containing 8 family, member B
chr1_-_97977233 1.175 ENSMUST00000161567.1
Pam
peptidylglycine alpha-amidating monooxygenase
chr13_-_97747373 1.163 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr18_-_82406777 1.142 ENSMUST00000065224.6
Galr1
galanin receptor 1
chr5_+_64812336 1.133 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr14_+_101840602 1.072 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr11_-_69605829 1.042 ENSMUST00000047889.6
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr16_+_43510267 1.041 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chr7_+_130936172 1.036 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr3_+_90537242 1.033 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr3_+_90537306 0.977 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr4_-_82705735 0.969 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr11_-_54028090 0.963 ENSMUST00000020586.6
Slc22a4
solute carrier family 22 (organic cation transporter), member 4
chr3_-_84305385 0.942 ENSMUST00000122849.1
ENSMUST00000132283.1
Trim2

tripartite motif-containing 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 152 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 1.9 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.4 1.9 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.3 1.9 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.3 1.9 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 1.8 GO:0034983 peptidyl-lysine deacetylation(GO:0034983) regulation of skeletal muscle fiber development(GO:0048742)
0.2 1.5 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.1 1.5 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 1.5 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.2 1.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.4 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.2 1.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 1.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.2 GO:0009404 toxin metabolic process(GO:0009404)
0.4 1.1 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.2 1.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 1.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 1.1 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.2 1.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.4 GO:0031526 brush border membrane(GO:0031526)
0.0 1.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.3 1.0 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 1.0 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 0.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.8 GO:0097542 ciliary tip(GO:0097542)
0.0 0.8 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.7 GO:0097513 myosin II filament(GO:0097513)
0.1 0.7 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 107 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.3 1.9 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 1.9 GO:0042805 actinin binding(GO:0042805)
0.1 1.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.6 GO:0008201 heparin binding(GO:0008201)
0.0 1.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.3 GO:0070064 proline-rich region binding(GO:0070064)
0.4 1.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 1.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.2 GO:0017022 myosin binding(GO:0017022)
0.3 1.1 GO:0004966 galanin receptor activity(GO:0004966)
0.3 1.1 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.1 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.1 GO:0001848 complement binding(GO:0001848)
0.2 1.0 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 1.0 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 1.0 GO:0043236 laminin binding(GO:0043236)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.5 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.4 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 2.3 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.1 1.5 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.2 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 1.2 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.2 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.0 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 0.9 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.8 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.7 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.7 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.7 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.6 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID_ARF6_PATHWAY Arf6 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.6 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 1.9 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.9 REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 1.7 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.5 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.1 1.4 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.1 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.1 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.1 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.1 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 1.0 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.9 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.8 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.8 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.8 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 0.7 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway