Motif ID: Neurod1

Z-value: 1.123


Transcription factors associated with Neurod1:

Gene SymbolEntrez IDGene Name
Neurod1 ENSMUSG00000034701.9 Neurod1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Neurod1mm10_v2_chr2_-_79456750_794567610.663.2e-06Click!


Activity profile for motif Neurod1.

activity profile for motif Neurod1


Sorted Z-values histogram for motif Neurod1

Sorted Z-values for motif Neurod1



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurod1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_69706326 8.044 ENSMUST00000182992.1
Ank3
ankyrin 3, epithelial
chr16_+_42907563 6.341 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr11_-_107915041 4.932 ENSMUST00000039071.2
Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr6_+_54681687 4.149 ENSMUST00000046276.6
2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr2_-_25319095 3.614 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr12_+_29528382 3.557 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr17_-_6449571 3.554 ENSMUST00000180035.1
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr7_+_121707189 3.291 ENSMUST00000065310.2
1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr6_-_136171722 3.264 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr6_-_121081589 3.180 ENSMUST00000077159.5
Mical3
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr13_-_97747399 3.150 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr2_-_29253001 3.092 ENSMUST00000071201.4
Ntng2
netrin G2
chr4_-_20778527 2.979 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chr10_-_110000219 2.908 ENSMUST00000032719.7
Nav3
neuron navigator 3
chr7_+_122289297 2.770 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr2_-_52558539 2.753 ENSMUST00000102760.3
ENSMUST00000102761.2
Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr5_+_123076275 2.707 ENSMUST00000067505.8
ENSMUST00000111619.3
ENSMUST00000160344.1
Tmem120b


transmembrane protein 120B


chr14_-_108914237 2.689 ENSMUST00000100322.2
Slitrk1
SLIT and NTRK-like family, member 1
chr5_-_28210022 2.645 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr12_-_34528844 2.528 ENSMUST00000110819.2
Hdac9
histone deacetylase 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 145 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 8.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 6.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 5.7 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 5.2 GO:0050808 synapse organization(GO:0050808)
0.2 4.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
1.5 4.4 GO:1900673 olefin metabolic process(GO:1900673)
0.0 4.1 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.3 4.0 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.6 3.9 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.4 3.8 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.3 3.8 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 3.4 GO:0010921 regulation of phosphatase activity(GO:0010921)
1.1 3.3 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.8 3.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 3.3 GO:0048665 neuron fate specification(GO:0048665)
0.1 3.2 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 2.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.6 2.8 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.3 2.8 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 2.7 GO:0022027 interkinetic nuclear migration(GO:0022027)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 68 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.4 8.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.3 7.2 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.2 4.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 4.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
1.1 4.4 GO:0044307 dendritic branch(GO:0044307)
0.2 3.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 3.8 GO:0031985 Golgi cisterna(GO:0031985)
0.0 3.8 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 2.8 GO:0031526 brush border membrane(GO:0031526)
0.1 2.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.7 GO:0005871 kinesin complex(GO:0005871)
0.0 2.7 GO:0072562 blood microparticle(GO:0072562)
0.0 2.7 GO:0005938 cell cortex(GO:0005938)
0.1 2.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 2.4 GO:0070545 PeBoW complex(GO:0070545)
0.1 2.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 2.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 2.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 2.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 98 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 7.6 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529)
0.1 7.6 GO:0030507 spectrin binding(GO:0030507)
0.0 6.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 4.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.3 4.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 4.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.5 4.0 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 3.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 3.7 GO:0051015 actin filament binding(GO:0051015)
0.2 3.3 GO:0001848 complement binding(GO:0001848)
0.1 3.3 GO:0005080 protein kinase C binding(GO:0005080)
0.1 3.2 GO:0071949 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) FAD binding(GO:0071949)
0.1 3.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 3.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 2.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 2.9 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.5 2.8 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 2.7 GO:0003777 microtubule motor activity(GO:0003777)
0.1 2.5 GO:0035497 cAMP response element binding(GO:0035497)
0.2 2.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.5 ST_GA13_PATHWAY G alpha 13 Pathway
0.1 5.9 PID_REELIN_PATHWAY Reelin signaling pathway
0.3 3.5 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 3.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 3.0 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 2.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.2 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 2.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.1 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 1.8 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.7 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.7 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 1.6 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.8 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.7 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.5 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 0.3 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 8.3 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 8.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 4.0 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.3 3.9 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 3.3 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 3.1 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.8 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 2.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 2.2 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.8 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.8 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 1.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 1.7 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.2 1.6 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 1.6 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.5 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 1.3 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.3 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.3 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo