Motif ID: Neurog2

Z-value: 0.451


Transcription factors associated with Neurog2:

Gene SymbolEntrez IDGene Name
Neurog2 ENSMUSG00000027967.7 Neurog2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Neurog2mm10_v2_chr3_+_127633134_1276331400.057.4e-01Click!


Activity profile for motif Neurog2.

activity profile for motif Neurog2


Sorted Z-values histogram for motif Neurog2

Sorted Z-values for motif Neurog2



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurog2

PNG image of the network

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Top targets:


Showing 1 to 20 of 177 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_129096740 1.489 ENSMUST00000056617.7
ENSMUST00000156437.1
 Gpr133

G protein-coupled receptor 133

chr13_-_97747399 1.429 ENSMUST00000144993.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr1_-_155232710 1.417 ENSMUST00000035914.3
 BC034090
cDNA sequence BC034090
chr2_-_79456750 1.251 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr9_-_58158498 1.162 ENSMUST00000168864.2
 Islr
immunoglobulin superfamily containing leucine-rich repeat
chr9_-_58159201 1.123 ENSMUST00000041477.7
 Islr
immunoglobulin superfamily containing leucine-rich repeat
chr16_+_43235856 1.061 ENSMUST00000146708.1
 Zbtb20
zinc finger and BTB domain containing 20
chr3_-_84259812 0.969 ENSMUST00000107691.1
 Trim2
tripartite motif-containing 2
chr19_+_20601958 0.922 ENSMUST00000087638.3
 Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr1_-_111864869 0.899 ENSMUST00000035462.5
 Dsel
dermatan sulfate epimerase-like
chr8_+_33428709 0.850 ENSMUST00000059351.7
 5930422O12Rik
RIKEN cDNA 5930422O12 gene
chr10_-_25200110 0.846 ENSMUST00000100012.2
 Akap7
A kinase (PRKA) anchor protein 7
chr4_+_9269285 0.827 ENSMUST00000038841.7
 Clvs1
clavesin 1
chr15_-_91191733 0.729 ENSMUST00000069511.6
 Abcd2
ATP-binding cassette, sub-family D (ALD), member 2
chr5_-_66618772 0.691 ENSMUST00000162994.1
ENSMUST00000159512.1
ENSMUST00000159786.1
 Apbb2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr10_+_69706326 0.684 ENSMUST00000182992.1
 Ank3
ankyrin 3, epithelial
chr11_+_58954675 0.630 ENSMUST00000047697.5
ENSMUST00000108817.3
 Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr1_+_15287259 0.621 ENSMUST00000175681.1
 Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr2_-_121807024 0.601 ENSMUST00000138157.1
 Frmd5
FERM domain containing 5
chr10_+_69534039 0.588 ENSMUST00000182557.1
 Ank3
ankyrin 3, epithelial

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 1.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 1.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 0.9 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 0.9 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.8 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.7 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.2 0.5 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402)
0.1 0.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.4 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.4 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.4 GO:0042701 progesterone secretion(GO:0042701)
0.1 0.4 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.4 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.4 GO:0031272 regulation of pseudopodium assembly(GO:0031272)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.8 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.3 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.2 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.3 GO:0070888 E-box binding(GO:0070888)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 0.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.9 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.8 GO:0016208 AMP binding(GO:0016208)
0.0 0.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 0.3 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 0.9 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.0 0.0 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones