Motif ID: Nhlh1
Z-value: 0.983

Transcription factors associated with Nhlh1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nhlh1 | ENSMUSG00000051251.3 | Nhlh1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nhlh1 | mm10_v2_chr1_-_172057573_172057598 | -0.01 | 9.7e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 412 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.1 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
0.1 | 2.9 | GO:0061029 | eyelid development in camera-type eye(GO:0061029) |
0.2 | 2.6 | GO:0044336 | canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336) |
0.0 | 2.6 | GO:0050821 | protein stabilization(GO:0050821) |
0.3 | 2.5 | GO:0098712 | L-glutamate import across plasma membrane(GO:0098712) |
0.2 | 2.5 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
0.2 | 2.4 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
0.2 | 2.4 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
0.0 | 2.3 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
0.6 | 2.2 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
0.5 | 2.1 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
0.3 | 1.8 | GO:0090383 | phagosome acidification(GO:0090383) |
0.2 | 1.6 | GO:0051461 | protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
0.1 | 1.6 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
0.1 | 1.6 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
0.0 | 1.6 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
0.2 | 1.5 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.1 | 1.5 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.1 | 1.5 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.5 | 1.4 | GO:0035934 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 137 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.7 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 4.0 | GO:0016605 | PML body(GO:0016605) |
0.1 | 3.0 | GO:0031941 | filamentous actin(GO:0031941) |
0.2 | 2.4 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.1 | 2.3 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.0 | 2.1 | GO:0014704 | intercalated disc(GO:0014704) |
0.3 | 2.0 | GO:0070695 | FHF complex(GO:0070695) |
0.0 | 2.0 | GO:0000776 | kinetochore(GO:0000776) |
0.1 | 1.9 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.0 | 1.7 | GO:0045335 | phagocytic vesicle(GO:0045335) |
0.4 | 1.6 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
0.2 | 1.5 | GO:0005883 | neurofilament(GO:0005883) |
0.5 | 1.4 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
0.2 | 1.4 | GO:0097427 | microtubule bundle(GO:0097427) |
0.0 | 1.4 | GO:0005814 | centriole(GO:0005814) |
0.0 | 1.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.1 | 1.3 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
0.1 | 1.3 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.3 | 1.2 | GO:0044307 | dendritic branch(GO:0044307) |
0.1 | 1.2 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 247 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 6.2 | GO:0003779 | actin binding(GO:0003779) |
0.0 | 5.3 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 3.9 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
0.0 | 3.5 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 3.3 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.1 | 3.2 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
0.1 | 3.0 | GO:0005112 | Notch binding(GO:0005112) |
0.1 | 2.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.6 | 2.6 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
0.6 | 2.4 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
0.1 | 2.4 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 2.4 | GO:0030414 | peptidase inhibitor activity(GO:0030414) |
0.1 | 2.3 | GO:0005109 | frizzled binding(GO:0005109) |
0.1 | 2.2 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
0.1 | 2.1 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 2.1 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
0.1 | 1.8 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.1 | 1.7 | GO:0043274 | phospholipase binding(GO:0043274) |
0.3 | 1.6 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.3 | 1.6 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 45 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.7 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.3 | 4.0 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
0.1 | 3.6 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 3.6 | PID_NOTCH_PATHWAY | Notch signaling pathway |
0.1 | 2.8 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.1 | 2.7 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
0.0 | 2.5 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
0.0 | 1.8 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
0.0 | 1.5 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.0 | 1.3 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
0.0 | 1.2 | PID_RHOA_PATHWAY | RhoA signaling pathway |
0.1 | 1.0 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.0 | 0.9 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
0.1 | 0.8 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.0 | 0.8 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
0.0 | 0.8 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
0.2 | 0.7 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
0.0 | 0.7 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.0 | 0.7 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 0.7 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 81 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.6 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
0.0 | 3.5 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 3.2 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.2 | 3.0 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
0.1 | 2.6 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.1 | 2.3 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
0.1 | 2.3 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.1 | 2.0 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.1 | 1.9 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.1 | 1.5 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.1 | 1.4 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
0.1 | 1.2 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.1 | 1.2 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.0 | 1.2 | REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION | Genes involved in TRAF6 mediated NF-kB activation |
0.0 | 1.2 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
0.0 | 1.2 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
0.0 | 1.2 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.1 | 1.1 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
0.1 | 1.1 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.3 | 1.0 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |