Motif ID: Nr2c1

Z-value: 0.550


Transcription factors associated with Nr2c1:

Gene SymbolEntrez IDGene Name
Nr2c1 ENSMUSG00000005897.8 Nr2c1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c1mm10_v2_chr10_+_94147982_94148023-0.241.3e-01Click!


Activity profile for motif Nr2c1.

activity profile for motif Nr2c1


Sorted Z-values histogram for motif Nr2c1

Sorted Z-values for motif Nr2c1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 111 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_58813359 4.138 ENSMUST00000135526.2
ENSMUST00000153031.1
 Sh3rf3

SH3 domain containing ring finger 3

chr15_+_80091320 3.259 ENSMUST00000009728.6
ENSMUST00000009727.5
 Syngr1

synaptogyrin 1

chr12_-_83487708 2.534 ENSMUST00000177959.1
ENSMUST00000178756.1
 Dpf3

D4, zinc and double PHD fingers, family 3

chr4_-_46991842 2.457 ENSMUST00000107749.2
 Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr1_-_155417283 2.283 ENSMUST00000027741.5
 Xpr1
xenotropic and polytropic retrovirus receptor 1
chr2_-_29253001 1.888 ENSMUST00000071201.4
 Ntng2
netrin G2
chr6_+_22875496 1.740 ENSMUST00000090568.3
 Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
chr9_-_29411736 1.668 ENSMUST00000115236.1
 Ntm
neurotrimin
chr15_+_3270767 1.665 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr10_-_86498836 1.660 ENSMUST00000120638.1
 Syn3
synapsin III
chr15_+_81811414 1.622 ENSMUST00000023024.7
 Tef
thyrotroph embryonic factor
chr11_-_26210553 1.597 ENSMUST00000101447.3
 5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr6_-_142964404 1.538 ENSMUST00000032421.3
 St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr9_-_21037775 1.531 ENSMUST00000180870.1
 Gm26592
predicted gene, 26592
chrX_+_10485121 1.488 ENSMUST00000076354.6
ENSMUST00000115526.1
 Tspan7

tetraspanin 7

chr10_+_127705170 1.412 ENSMUST00000079590.5
 Myo1a
myosin IA
chr4_+_133039482 1.395 ENSMUST00000105914.1
 Ahdc1
AT hook, DNA binding motif, containing 1
chr1_-_58586191 1.352 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
 Fam126b



family with sequence similarity 126, member B



chr9_-_29412204 1.245 ENSMUST00000115237.1
 Ntm
neurotrimin
chr7_+_45896941 1.206 ENSMUST00000069772.7
ENSMUST00000107716.1
 Tmem143

transmembrane protein 143


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 2.6 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.1 2.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.4 2.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 2.0 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 2.0 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.6 1.7 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.0 1.7 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 1.4 GO:0030033 microvillus assembly(GO:0030033)
0.4 1.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 1.2 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.2 1.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 1.1 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 1.0 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.9 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.9 GO:0001553 luteinization(GO:0001553)
0.0 0.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.3 0.8 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.9 GO:0031225 anchored component of membrane(GO:0031225)
0.5 2.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 2.5 GO:0071565 nBAF complex(GO:0071565)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.6 1.7 GO:0072534 perineuronal net(GO:0072534)
0.1 1.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 1.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 1.1 GO:0030673 axolemma(GO:0030673)
0.0 0.9 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.7 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.6 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.8 2.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 1.8 GO:0003774 motor activity(GO:0003774)
0.1 1.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.3 1.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 1.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 1.2 GO:0050811 GABA receptor binding(GO:0050811)
0.4 1.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.0 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 0.7 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.9 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.9 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID_ARF_3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 2.3 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 1.4 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 1.1 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.8 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.8 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.7 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins