Motif ID: Nr2e1

Z-value: 0.451


Transcription factors associated with Nr2e1:

Gene SymbolEntrez IDGene Name
Nr2e1 ENSMUSG00000019803.5 Nr2e1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2e1mm10_v2_chr10_-_42583628_42583639-0.516.8e-04Click!


Activity profile for motif Nr2e1.

activity profile for motif Nr2e1


Sorted Z-values histogram for motif Nr2e1

Sorted Z-values for motif Nr2e1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2e1

PNG image of the network

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Top targets:


Showing 1 to 20 of 41 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_114768736 1.759 ENSMUST00000117543.1
 Insc
inscuteable homolog (Drosophila)
chr4_+_33924632 1.491 ENSMUST00000057188.6
 Cnr1
cannabinoid receptor 1 (brain)
chrX_-_95658379 1.201 ENSMUST00000119640.1
 Zc4h2
zinc finger, C4H2 domain containing
chrX_-_95658392 1.170 ENSMUST00000120620.1
 Zc4h2
zinc finger, C4H2 domain containing
chr4_-_35845204 1.130 ENSMUST00000164772.1
ENSMUST00000065173.2
 Lingo2

leucine rich repeat and Ig domain containing 2

chr14_+_32028989 1.054 ENSMUST00000022460.4
 Galnt15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chrX_-_95658416 1.034 ENSMUST00000044382.6
 Zc4h2
zinc finger, C4H2 domain containing
chrX_-_143827391 0.897 ENSMUST00000087316.5
 Capn6
calpain 6
chr4_-_63403330 0.811 ENSMUST00000035724.4
 Akna
AT-hook transcription factor
chr9_-_58158498 0.771 ENSMUST00000168864.2
 Islr
immunoglobulin superfamily containing leucine-rich repeat
chr4_-_119415494 0.640 ENSMUST00000063642.2
 Ccdc30
coiled-coil domain containing 30
chr10_+_18469958 0.583 ENSMUST00000162891.1
ENSMUST00000100054.3
 Nhsl1

NHS-like 1

chr15_-_10485385 0.550 ENSMUST00000168690.1
 Brix1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr4_+_32238950 0.519 ENSMUST00000037416.6
 Bach2
BTB and CNC homology 2
chr2_-_73386396 0.474 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
 Gpr155


G protein-coupled receptor 155


chr4_+_28813125 0.453 ENSMUST00000029964.5
ENSMUST00000080934.4
 Epha7

Eph receptor A7

chr1_-_132390301 0.448 ENSMUST00000132435.1
 Tmcc2
transmembrane and coiled-coil domains 2
chr10_-_61784014 0.404 ENSMUST00000020283.4
 H2afy2
H2A histone family, member Y2
chrX_-_139998519 0.355 ENSMUST00000113007.1
ENSMUST00000033810.7
ENSMUST00000113011.2
ENSMUST00000087400.5
 Rbm41



RNA binding motif protein 41



chr15_+_41830921 0.344 ENSMUST00000166917.1
 Oxr1
oxidation resistance 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.4 1.5 GO:0031622 positive regulation of fever generation(GO:0031622) trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0 1.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.9 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.8 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.6 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.4 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 0.3 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0032782 bile acid secretion(GO:0032782)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.5 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.4 GO:0001740 Barr body(GO:0001740)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)

Gene overrepresentation in molecular_function category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.5 GO:0008144 drug binding(GO:0008144)
0.1 1.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 1.0 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.8 PID_EPHA_FWDPATHWAY EPHA forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)