Motif ID: Obox1

Z-value: 0.662


Transcription factors associated with Obox1:

Gene SymbolEntrez IDGene Name
Obox1 ENSMUSG00000054310.10 Obox1



Activity profile for motif Obox1.

activity profile for motif Obox1


Sorted Z-values histogram for motif Obox1

Sorted Z-values for motif Obox1



Network of associatons between targets according to the STRING database.



First level regulatory network of Obox1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_53975246 3.819 ENSMUST00000048409.7
 Elmod1
ELMO/CED-12 domain containing 1
chr16_+_23290464 3.416 ENSMUST00000115335.1
 St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr14_+_61138445 2.907 ENSMUST00000089394.3
ENSMUST00000119509.1
 Sacs

sacsin

chr6_+_80018877 2.896 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
 Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr6_+_80019008 2.720 ENSMUST00000126399.1
ENSMUST00000136421.1
 Lrrtm4

leucine rich repeat transmembrane neuronal 4

chr6_+_58833689 2.539 ENSMUST00000041401.8
 Herc3
hect domain and RLD 3
chr3_-_85722474 2.378 ENSMUST00000119077.1
 Fam160a1
family with sequence similarity 160, member A1
chr2_-_104257400 2.285 ENSMUST00000141159.1
 D430041D05Rik
RIKEN cDNA D430041D05 gene
chr11_+_70017199 2.157 ENSMUST00000133140.1
 Dlg4
discs, large homolog 4 (Drosophila)
chr11_+_70017085 2.037 ENSMUST00000108589.2
 Dlg4
discs, large homolog 4 (Drosophila)
chr12_+_12262139 1.987 ENSMUST00000069066.6
ENSMUST00000069005.8
 Fam49a

family with sequence similarity 49, member A

chr16_+_31422268 1.970 ENSMUST00000089759.2
 Bdh1
3-hydroxybutyrate dehydrogenase, type 1
chr8_-_109251698 1.951 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr5_-_37717122 1.885 ENSMUST00000094836.4
 Stk32b
serine/threonine kinase 32B
chr7_-_42578588 1.833 ENSMUST00000179470.1
 Gm21028
predicted gene, 21028
chr14_-_54781886 1.813 ENSMUST00000022787.6
 Slc7a8
solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
chr10_-_86732409 1.699 ENSMUST00000070435.4
 Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr18_-_43393346 1.696 ENSMUST00000025379.7
 Dpysl3
dihydropyrimidinase-like 3
chr14_+_32166104 1.587 ENSMUST00000164341.1
 Ncoa4
nuclear receptor coactivator 4
chr17_+_8525369 1.510 ENSMUST00000115715.1
 Pde10a
phosphodiesterase 10A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 93 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 9.8 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 3.6 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.9 3.4 GO:2000110 protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110)
0.1 2.4 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 1.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.8 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 1.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.6 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.2 1.2 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.2 1.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 1.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 1.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 1.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.2 1.0 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.0 1.0 GO:0043171 peptide catabolic process(GO:0043171)
0.3 0.9 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 9.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 3.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 2.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.2 GO:0005811 lipid particle(GO:0005811)
0.0 2.1 GO:0043204 perikaryon(GO:0043204)
0.2 1.7 GO:0001739 sex chromatin(GO:0001739)
0.0 1.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.6 GO:0044754 autolysosome(GO:0044754)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.4 1.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 1.1 GO:0002177 manchette(GO:0002177)
0.1 1.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.2 0.9 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 0.9 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.9 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 0.8 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.2 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.5 4.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.7 3.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 2.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 2.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.7 2.0 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.3 1.8 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 1.8 GO:0019534 organic cation transmembrane transporter activity(GO:0015101) toxin transporter activity(GO:0019534)
0.1 1.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 1.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 1.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.7 GO:0070064 proline-rich region binding(GO:0070064)
0.2 1.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 1.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.4 1.2 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.4 1.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 1.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3 1.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 1.1 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)

Gene overrepresentation in C2:CP category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.4 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 2.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.9 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.8 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.7 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.6 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.9 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.5 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.4 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.3 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.3 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.2 PID_IL23_PATHWAY IL23-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.0 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.2 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 1.8 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 1.8 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 1.7 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.7 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 1.5 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.4 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.2 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 1.1 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.8 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.8 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.8 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.8 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.1 0.6 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.6 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription