ISMARA results: Pax3

Motif ID: Pax3

Z-value: 0.495

Transcription factors associated with Pax3:

Gene Symbol	Entrez ID	Gene Name
Pax3	ENSMUSG00000004872.9	Pax3

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Pax3	mm10_v2_chr1_-_78196832_78196845	0.26	9.5e-02	Click!

View svg image
View png image

Top targets:

Search:

Show entries

Showing 1 to 20 of 39 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_136387929	2.120	ENSMUST00000035264.2 ENSMUST00000077200.3	Pak7	p21 protein (Cdc42/Rac)-activated kinase 7
chr10_+_82138253	1.981	ENSMUST00000105314.2	AU041133	expressed sequence AU041133
chr4_+_127077374	1.960	ENSMUST00000046751.6 ENSMUST00000094713.3	Zmym6	zinc finger, MYM-type 6
chr9_-_40346290	1.822	ENSMUST00000121357.1	Gramd1b	GRAM domain containing 1B
chr14_+_51893610	1.727	ENSMUST00000047726.5 ENSMUST00000161888.1	Slc39a2	solute carrier family 39 (zinc transporter), member 2
chr2_+_102659213	1.602	ENSMUST00000111213.1	Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr12_+_52699297	1.540	ENSMUST00000095737.3	Akap6	A kinase (PRKA) anchor protein 6
chrX_+_159840463	1.314	ENSMUST00000112451.1 ENSMUST00000112453.2	Sh3kbp1	SH3-domain kinase binding protein 1
chrX_-_103623648	1.278	ENSMUST00000156211.1	Ftx	Ftx transcript, Xist regulator (non-protein coding)
chr10_-_70592782	1.265	ENSMUST00000162251.1	Phyhipl	phytanoyl-CoA hydroxylase interacting protein-like
chr8_+_71887264	1.227	ENSMUST00000034259.7	Zfp709	zinc finger protein 709
chr12_+_38781093	1.042	ENSMUST00000161513.1	Etv1	ets variant gene 1
chr12_+_38780817	1.023	ENSMUST00000160856.1	Etv1	ets variant gene 1
chr12_+_38780284	0.999	ENSMUST00000162563.1 ENSMUST00000161164.1 ENSMUST00000160996.1	Etv1	ets variant gene 1
chr18_+_35562158	0.995	ENSMUST00000166793.1	Matr3	matrin 3
chr16_-_32877723	0.974	ENSMUST00000119810.1	1700021K19Rik	RIKEN cDNA 1700021K19 gene
chr3_+_36159522	0.963	ENSMUST00000165956.2	D3Ertd254e	DNA segment, Chr 3, ERATO Doi 254, expressed
chrX_-_103623704	0.864	ENSMUST00000130063.1 ENSMUST00000125419.1	Ftx	Ftx transcript, Xist regulator (non-protein coding)
chr8_+_33428709	0.853	ENSMUST00000059351.7	5930422O12Rik	RIKEN cDNA 5930422O12 gene
chr17_+_21691860	0.812	ENSMUST00000072133.4	Gm10226	predicted gene 10226

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Showing 1 to 15 of 15 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.1	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4	2.1	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	2.1	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.1	1.7	GO:0006829	zinc II ion transport(GO:0006829)
0.2	1.6	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4	1.5	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0	1.2	GO:0034605	cellular response to heat(GO:0034605)
0.2	0.7	GO:0071638	negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0	0.7	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.7	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.7	GO:0003170	heart valve development(GO:0003170)
0.0	0.7	GO:0006406	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1	0.4	GO:0018307	tRNA wobble position uridine thiolation(GO:0002143) enzyme active site formation(GO:0018307)
0.0	0.3	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.3	GO:0007413	axonal fasciculation(GO:0007413)

Gene overrepresentation in cellular_component category:

Search:

Show entries

Showing 1 to 5 of 5 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.6	GO:0030673	axolemma(GO:0030673)
0.1	1.5	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.7	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.3	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.2	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)

Gene overrepresentation in molecular_function category:

Search:

Show entries

Showing 1 to 8 of 8 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.1	GO:0048365	Rac GTPase binding(GO:0048365)
0.1	1.7	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.3	1.6	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.1	1.5	GO:0043495	protein anchor(GO:0043495)
0.2	0.7	GO:0004686	elongation factor-2 kinase activity(GO:0004686)
0.0	0.7	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	0.4	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.3	GO:0030346	protein phosphatase 2B binding(GO:0030346)

Gene overrepresentation in C2:CP category:

Search:

Show entries

Showing 1 to 5 of 5 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.1	PID_P38_MK2_PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	2.1	SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	1.3	PID_ERBB1_INTERNALIZATION_PATHWAY	Internalization of ErbB1
0.0	0.7	PID_P38_GAMMA_DELTA_PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.7	PID_IL4_2PATHWAY	IL4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Showing 1 to 6 of 6 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	REACTOME_ACTIVATION_OF_RAC	Genes involved in Activation of Rac
0.1	1.7	REACTOME_ZINC_TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.6	REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	1.3	REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.7	REACTOME_MTORC1_MEDIATED_SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.2	REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane