Motif ID: Pgr_Nr3c1

Z-value: 0.548

Transcription factors associated with Pgr_Nr3c1:

Gene SymbolEntrez IDGene Name
Nr3c1 ENSMUSG00000024431.8 Nr3c1
Pgr ENSMUSG00000031870.10 Pgr

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr3c1mm10_v2_chr18_-_39487096_394872450.143.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pgr_Nr3c1

PNG image of the network

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Top targets:


Showing 1 to 20 of 134 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_20665250 11.911 ENSMUST00000075312.3
Ttr
transthyretin
chr10_+_97565436 3.437 ENSMUST00000038160.4
Lum
lumican
chr13_-_84064772 2.971 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr9_+_91368811 1.511 ENSMUST00000173054.1
Zic4
zinc finger protein of the cerebellum 4
chr9_-_79718631 1.417 ENSMUST00000180083.1
Col12a1
collagen, type XII, alpha 1
chr18_-_62756275 1.400 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr9_-_79718518 1.243 ENSMUST00000071750.6
Col12a1
collagen, type XII, alpha 1
chr5_+_24364804 1.238 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr9_+_91368970 1.236 ENSMUST00000172646.1
Zic4
zinc finger protein of the cerebellum 4
chr14_-_16575456 1.143 ENSMUST00000063750.6
Rarb
retinoic acid receptor, beta
chr9_-_79718720 1.110 ENSMUST00000121227.1
Col12a1
collagen, type XII, alpha 1
chr7_+_144838590 0.908 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr4_-_136898803 0.729 ENSMUST00000046285.5
C1qa
complement component 1, q subcomponent, alpha polypeptide
chr13_+_29016267 0.691 ENSMUST00000140415.1
A330102I10Rik
RIKEN cDNA A330102I10 gene
chr2_-_154613425 0.649 ENSMUST00000181369.1
4930519P11Rik
RIKEN cDNA 4930519P11 gene
chr2_-_122611238 0.478 ENSMUST00000028624.8
Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr10_-_116473418 0.472 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr4_-_119422355 0.467 ENSMUST00000106316.1
ENSMUST00000030385.6
Ppcs

phosphopantothenoylcysteine synthetase

chr13_+_91461050 0.442 ENSMUST00000004094.8
ENSMUST00000042122.8
Ssbp2

single-stranded DNA binding protein 2

chr2_+_91256144 0.430 ENSMUST00000154959.1
ENSMUST00000059566.4
Pacsin3

protein kinase C and casein kinase substrate in neurons 3


Gene overrepresentation in biological_process category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.4 11.9 GO:0070327 thyroid hormone transport(GO:0070327)
0.9 3.4 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.4 1.2 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.2 1.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.8 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.6 GO:0097320 membrane tubulation(GO:0097320)
0.2 0.5 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.3 GO:0055099 response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.3 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.3 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.2 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 0.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 0.2 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 3.8 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.3 3.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.3 GO:0005901 caveola(GO:0005901)
0.0 0.8 GO:0005581 collagen trimer(GO:0005581)
0.1 0.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 11.9 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 3.8 GO:0005518 collagen binding(GO:0005518)
0.4 1.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 1.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.5 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.3 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.2 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)

Gene overrepresentation in C2:CP category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 11.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.8 NABA_COLLAGENS Genes encoding collagen proteins
0.1 3.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.4 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.2 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 11.9 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 3.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.3 3.4 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.2 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.9 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 0.7 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 0.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins