Motif ID: Phox2a

Z-value: 0.579


Transcription factors associated with Phox2a:

Gene SymbolEntrez IDGene Name
Phox2a ENSMUSG00000007946.9 Phox2a



Activity profile for motif Phox2a.

activity profile for motif Phox2a


Sorted Z-values histogram for motif Phox2a

Sorted Z-values for motif Phox2a



Network of associatons between targets according to the STRING database.



First level regulatory network of Phox2a

PNG image of the network

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Top targets:


Showing 1 to 20 of 25 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_60893430 7.941 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr2_+_20737306 6.577 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr2_-_168767136 3.984 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr2_-_168767029 3.746 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr4_-_14621805 2.436 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr9_+_119063429 2.402 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr4_-_14621669 1.762 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr13_-_102906046 1.750 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr13_-_102905740 1.728 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr4_-_14621494 1.611 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr1_-_172027269 1.123 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr8_-_84662841 1.084 ENSMUST00000060427.4
Ier2
immediate early response 2
chr15_-_67113909 0.768 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr6_-_147264124 0.762 ENSMUST00000052296.6
Pthlh
parathyroid hormone-like peptide
chr1_-_89933290 0.581 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr7_-_38019505 0.432 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr3_+_66219909 0.425 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chrX_+_9885622 0.424 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr4_+_134930898 0.405 ENSMUST00000030622.2
Syf2
SYF2 homolog, RNA splicing factor (S. cerevisiae)
chr19_-_41933276 0.297 ENSMUST00000075280.4
ENSMUST00000112123.2
Exosc1

exosome component 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 7.9 GO:0007530 sex determination(GO:0007530)
0.4 7.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 6.6 GO:0048706 embryonic skeletal system development(GO:0048706)
0.8 5.8 GO:0019532 oxalate transport(GO:0019532)
0.1 2.4 GO:0051693 actin filament capping(GO:0051693)
0.4 1.1 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 1.1 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.1 0.8 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.6 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 0.4 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.7 GO:0000792 heterochromatin(GO:0000792)
0.0 5.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.3 1.1 GO:0060187 cell pole(GO:0060187)
0.0 0.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)

Gene overrepresentation in molecular_function category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 8.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.5 5.8 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.0 3.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 2.4 GO:0051015 actin filament binding(GO:0051015)
0.2 0.8 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.6 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.7 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.8 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease