ISMARA results: Plagl1

Motif ID: Plagl1

Z-value: 0.419

Transcription factors associated with Plagl1:

Gene Symbol	Entrez ID	Gene Name
Plagl1	ENSMUSG00000019817.12	Plagl1

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Plagl1	mm10_v2_chr10_+_13090788_13090843	-0.64	7.6e-06	Click!

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Showing 1 to 20 of 118 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_152338619	1.686	ENSMUST00000030775.5 ENSMUST00000164662.1	Chd5	chromodomain helicase DNA binding protein 5
chr17_+_46297406	1.575	ENSMUST00000061722.6 ENSMUST00000166280.1	Dlk2	delta-like 2 homolog (Drosophila)
chr2_-_104257400	1.419	ENSMUST00000141159.1	D430041D05Rik	RIKEN cDNA D430041D05 gene
chr5_-_139130159	1.408	ENSMUST00000129851.1	Prkar1b	protein kinase, cAMP dependent regulatory, type I beta
chr6_-_91807424	1.374	ENSMUST00000162300.1	Grip2	glutamate receptor interacting protein 2
chr6_-_91807318	1.105	ENSMUST00000159684.1	Grip2	glutamate receptor interacting protein 2
chr17_+_46297917	1.073	ENSMUST00000166617.1 ENSMUST00000170271.1	Dlk2	delta-like 2 homolog (Drosophila)
chr17_-_24644933	0.994	ENSMUST00000019684.5	Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr3_+_26331150	0.898	ENSMUST00000099182.2	A830092H15Rik	RIKEN cDNA A830092H15 gene
chr10_-_81482655	0.873	ENSMUST00000120508.1 ENSMUST00000118763.1	Celf5	CUGBP, Elav-like family member 5
chr19_+_6497772	0.849	ENSMUST00000113458.1 ENSMUST00000113459.1	Nrxn2	neurexin II
chr4_+_129136948	0.832	ENSMUST00000102600.3	Fndc5	fibronectin type III domain containing 5
chr15_-_43869993	0.804	ENSMUST00000067469.4	Tmem74	transmembrane protein 74
chr4_-_22488296	0.789	ENSMUST00000178174.1	Pou3f2	POU domain, class 3, transcription factor 2
chr11_-_120047144	0.775	ENSMUST00000103020.1	Aatk	apoptosis-associated tyrosine kinase
chr7_-_99695809	0.749	ENSMUST00000107086.2	Slco2b1	solute carrier organic anion transporter family, member 2b1
chr10_+_38965515	0.723	ENSMUST00000019992.5	Lama4	laminin, alpha 4
chr10_-_81014902	0.691	ENSMUST00000126317.1 ENSMUST00000092285.3 ENSMUST00000117805.1	Gng7	guanine nucleotide binding protein (G protein), gamma 7
chr18_+_32377176	0.674	ENSMUST00000091967.5 ENSMUST00000025239.7	Bin1	bridging integrator 1
chrX_+_163911401	0.673	ENSMUST00000140845.1	Ap1s2	adaptor-related protein complex 1, sigma 2 subunit

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Showing 1 to 20 of 50 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.6	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.2	2.5	GO:0014824	artery smooth muscle contraction(GO:0014824)
0.2	1.7	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1	1.4	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.4	1.1	GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.2	1.1	GO:0046684	response to pyrethroid(GO:0046684)
0.0	1.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.9	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	0.8	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.1	0.8	GO:0032482	Rab protein signal transduction(GO:0032482)
0.1	0.8	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.8	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.8	GO:0042297	vocal learning(GO:0042297) imitative learning(GO:0098596)
0.1	0.7	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1	0.7	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.1	0.7	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.1	0.7	GO:0099628	receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0	0.7	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.7	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.6	GO:0043589	skin morphogenesis(GO:0043589)

Gene overrepresentation in cellular_component category:

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Showing 1 to 20 of 20 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.5	GO:0043198	dendritic shaft(GO:0043198)
0.1	1.7	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	1.4	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	1.3	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.1	1.1	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.9	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.9	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.8	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.7	GO:0005605	basal lamina(GO:0005605)
0.2	0.6	GO:0005584	collagen type I trimer(GO:0005584)
0.0	0.6	GO:0031201	SNARE complex(GO:0031201)
0.0	0.5	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.0	0.5	GO:0032420	stereocilium(GO:0032420)
0.0	0.4	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	0.4	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.4	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	0.3	GO:0008091	spectrin(GO:0008091)
0.0	0.3	GO:0005869	dynactin complex(GO:0005869)
0.0	0.2	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.2	GO:0030127	COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular_function category:

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Showing 1 to 20 of 33 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.5	GO:0035254	glutamate receptor binding(GO:0035254)
0.4	1.7	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.1	1.4	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.4	1.1	GO:0002153	steroid receptor RNA activator RNA binding(GO:0002153)
0.1	1.1	GO:0031402	sodium ion binding(GO:0031402)
0.0	1.0	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.1	0.8	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.8	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.8	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.8	GO:0005179	hormone activity(GO:0005179)
0.1	0.7	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.1	0.7	GO:0031811	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1	0.6	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.0	0.6	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	0.5	GO:0070905	serine binding(GO:0070905)
0.1	0.5	GO:0071253	connexin binding(GO:0071253)
0.1	0.4	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.4	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.4	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.4	GO:0048156	tau protein binding(GO:0048156)

Gene overrepresentation in C2:CP category:

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Showing 1 to 14 of 14 entries

Total log-likelihood	Term	Description
1.4	PID_INTEGRIN3_PATHWAY	Beta3 integrin cell surface interactions
1.4	PID_INTEGRIN_A4B1_PATHWAY	Alpha4 beta1 integrin signaling events
1.1	PID_RXR_VDR_PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
1.0	PID_LYSOPHOSPHOLIPID_PATHWAY	LPA receptor mediated events
0.7	ST_GA12_PATHWAY	G alpha 12 Pathway
0.7	PID_ARF6_TRAFFICKING_PATHWAY	Arf6 trafficking events
0.6	NABA_COLLAGENS	Genes encoding collagen proteins
0.6	PID_RHOA_PATHWAY	RhoA signaling pathway
0.6	PID_IL2_1PATHWAY	IL2-mediated signaling events
0.4	SA_PROGRAMMED_CELL_DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3	PID_NCADHERIN_PATHWAY	N-cadherin signaling events
0.2	PID_S1P_S1P1_PATHWAY	S1P1 pathway
0.2	PID_PDGFRA_PATHWAY	PDGFR-alpha signaling pathway
0.2	PID_WNT_CANONICAL_PATHWAY	Canonical Wnt signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

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Showing 1 to 15 of 15 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.5	REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	1.4	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	1.1	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.9	REACTOME_G_PROTEIN_ACTIVATION	Genes involved in G-protein activation
0.0	0.8	REACTOME_GLUTATHIONE_CONJUGATION	Genes involved in Glutathione conjugation
0.1	0.7	REACTOME_TRANSPORT_OF_ORGANIC_ANIONS	Genes involved in Transport of organic anions
0.0	0.7	REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.6	REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.6	REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.6	REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.5	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.5	REACTOME_LYSOSOME_VESICLE_BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.4	REACTOME_INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.4	REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.3	REACTOME_CA_DEPENDENT_EVENTS	Genes involved in Ca-dependent events