Motif ID: Pou2f1
Z-value: 0.829
Transcription factors associated with Pou2f1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Pou2f1 | ENSMUSG00000026565.12 | Pou2f1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Pou2f1 | mm10_v2_chr1_-_166002591_166002609 | -0.36 | 2.2e-02 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 80 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 4.0 | GO:0021773 | striatal medium spiny neuron differentiation(GO:0021773) |
| 0.2 | 3.5 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
| 0.0 | 3.2 | GO:0008542 | visual learning(GO:0008542) |
| 1.0 | 3.1 | GO:0072284 | cervix development(GO:0060067) metanephric S-shaped body morphogenesis(GO:0072284) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744) |
| 0.0 | 2.7 | GO:0006333 | chromatin assembly or disassembly(GO:0006333) |
| 0.0 | 2.6 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 2.4 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.4 | 2.2 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.0 | 1.7 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.2 | 1.5 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.5 | 1.4 | GO:0030210 | heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014) |
| 0.2 | 1.4 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.4 | 1.3 | GO:1902605 | heterotrimeric G-protein complex assembly(GO:1902605) |
| 0.3 | 1.3 | GO:0060025 | regulation of synaptic activity(GO:0060025) |
| 0.2 | 1.3 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
| 0.2 | 1.3 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 0.1 | 1.3 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
| 0.0 | 1.3 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
| 0.2 | 1.2 | GO:1902412 | regulation of mitotic cytokinesis(GO:1902412) |
| 0.4 | 1.1 | GO:1901421 | positive regulation of response to alcohol(GO:1901421) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 41 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 6.2 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.0 | 2.7 | GO:0043679 | axon terminus(GO:0043679) |
| 0.2 | 2.2 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 2.1 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.2 | 1.3 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) |
| 0.1 | 1.3 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 1.3 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 1.3 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.2 | 1.2 | GO:0000235 | astral microtubule(GO:0000235) |
| 0.2 | 1.0 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.0 | 1.0 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 0.8 | GO:0005753 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) |
| 0.2 | 0.7 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.1 | 0.7 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 0.0 | 0.7 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 0.7 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.7 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.7 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.1 | 0.6 | GO:0060091 | kinocilium(GO:0060091) |
| 0.1 | 0.6 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 55 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.4 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.2 | 3.2 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 2.4 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.1 | 2.2 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.0 | 1.7 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.4 | 1.5 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.1 | 1.4 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.2 | 1.3 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.2 | 1.3 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
| 0.1 | 1.3 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.0 | 1.3 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 1.1 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.0 | 1.1 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 1.0 | GO:0005536 | glucose binding(GO:0005536) |
| 0.0 | 1.0 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 1.0 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 1.0 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 1.0 | GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655) |
| 0.1 | 0.9 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.2 | 0.8 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
Gene overrepresentation in C2:CP category:
Showing 1 to 17 of 17 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.5 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 3.2 | PID_AP1_PATHWAY | AP-1 transcription factor network |
| 0.0 | 2.5 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 2.2 | NABA_COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.6 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
| 0.0 | 1.5 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 1.5 | PID_SHP2_PATHWAY | SHP2 signaling |
| 0.0 | 1.4 | PID_RHOA_PATHWAY | RhoA signaling pathway |
| 0.0 | 1.3 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 1.0 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 1.0 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
| 0.0 | 1.0 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
| 0.0 | 0.8 | ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.0 | 0.7 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.7 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 0.6 | PID_CD40_PATHWAY | CD40/CD40L signaling |
| 0.0 | 0.6 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 24 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.2 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.1 | 3.5 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 2.2 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 2.0 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.2 | 1.5 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.1 | 1.4 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.1 | 1.4 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 1.3 | REACTOME_INTEGRATION_OF_PROVIRUS | Genes involved in Integration of provirus |
| 0.1 | 1.3 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 1.1 | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.0 | 1.1 | REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.0 | 1.0 | REACTOME_GLUCOSE_TRANSPORT | Genes involved in Glucose transport |
| 0.0 | 0.9 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.8 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.8 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.2 | 0.7 | REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.0 | 0.7 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
| 0.0 | 0.6 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.6 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.0 | 0.4 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
