Motif ID: Pou2f3

Z-value: 0.677


Transcription factors associated with Pou2f3:

Gene SymbolEntrez IDGene Name
Pou2f3 ENSMUSG00000032015.9 Pou2f3



Activity profile for motif Pou2f3.

activity profile for motif Pou2f3


Sorted Z-values histogram for motif Pou2f3

Sorted Z-values for motif Pou2f3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou2f3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_53845086 6.487 ENSMUST00000108014.1
 Gm10985
predicted gene 10985
chr1_-_166002613 2.348 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
 Pou2f1



POU domain, class 2, transcription factor 1



chr9_-_58313189 1.887 ENSMUST00000061799.8
 Loxl1
lysyl oxidase-like 1
chr13_+_94173992 1.881 ENSMUST00000121618.1
 Lhfpl2
lipoma HMGIC fusion partner-like 2
chr5_-_109558957 1.404 ENSMUST00000044579.7
 Crlf2
cytokine receptor-like factor 2
chr18_-_82406777 1.247 ENSMUST00000065224.6
 Galr1
galanin receptor 1
chr1_-_75278345 1.190 ENSMUST00000039534.4
 Resp18
regulated endocrine-specific protein 18
chr6_-_136875794 1.111 ENSMUST00000032342.1
 Mgp
matrix Gla protein
chr6_+_125215551 1.093 ENSMUST00000032487.7
ENSMUST00000100942.2
ENSMUST00000063588.8
 Vamp1


vesicle-associated membrane protein 1


chrX_-_23266751 0.986 ENSMUST00000115316.2
 Klhl13
kelch-like 13
chr13_+_29016267 0.943 ENSMUST00000140415.1
 A330102I10Rik
RIKEN cDNA A330102I10 gene
chr7_-_42578588 0.908 ENSMUST00000179470.1
 Gm21028
predicted gene, 21028
chr17_-_47691403 0.886 ENSMUST00000113299.1
ENSMUST00000152214.1
 Gm21981
Prickle4
predicted gene 21981
prickle homolog 4 (Drosophila)
chr7_+_81523555 0.873 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
 2900076A07Rik



RIKEN cDNA 2900076A07 gene



chr15_+_92597104 0.839 ENSMUST00000035399.8
 Pdzrn4
PDZ domain containing RING finger 4
chr4_-_24851079 0.837 ENSMUST00000084781.5
ENSMUST00000108218.3
 Klhl32

kelch-like 32

chr14_-_100149764 0.815 ENSMUST00000097079.4
 Klf12
Kruppel-like factor 12
chr7_+_81523531 0.813 ENSMUST00000181903.1
 2900076A07Rik
RIKEN cDNA 2900076A07 gene
chr2_-_144527341 0.780 ENSMUST00000163701.1
ENSMUST00000081982.5
 Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr1_-_166002591 0.777 ENSMUST00000111429.4
ENSMUST00000176800.1
 Pou2f1

POU domain, class 2, transcription factor 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 3.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.2 1.4 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.1 1.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 1.2 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.1 1.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.2 0.9 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 0.8 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.8 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.2 0.7 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.1 0.7 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 0.6 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 0.6 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 0.6 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.6 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.6 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.1 0.6 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.2 0.5 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.2 0.5 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.8 GO:0005604 basement membrane(GO:0005604)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 1.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 1.1 GO:0070820 tertiary granule(GO:0070820)
0.1 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.7 GO:0005605 basal lamina(GO:0005605)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.4 GO:0071920 cleavage body(GO:0071920)
0.0 0.4 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 1.9 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 1.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.8 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.7 GO:0031402 sodium ion binding(GO:0031402)
0.2 0.6 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.1 0.6 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.6 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.6 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.6 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.6 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.2 0.5 GO:0098809 nitrite reductase activity(GO:0098809)
0.2 0.5 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.5 GO:0050816 phosphothreonine binding(GO:0050816)

Gene overrepresentation in C2:CP category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.9 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.6 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.1 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.0 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.2 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.1 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.1 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.6 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.5 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.1 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.1 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions