Motif ID: Pou4f3

Z-value: 0.331


Transcription factors associated with Pou4f3:

Gene SymbolEntrez IDGene Name
Pou4f3 ENSMUSG00000024497.3 Pou4f3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou4f3mm10_v2_chr18_+_42394539_423945750.067.3e-01Click!


Activity profile for motif Pou4f3.

activity profile for motif Pou4f3


Sorted Z-values histogram for motif Pou4f3

Sorted Z-values for motif Pou4f3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou4f3

PNG image of the network

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Top targets:


Showing 1 to 20 of 49 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_37139558 1.232 ENSMUST00000062667.3
 5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr4_-_58499398 1.182 ENSMUST00000107570.1
 Lpar1
lysophosphatidic acid receptor 1
chr11_+_114675431 0.813 ENSMUST00000045779.5
 Ttyh2
tweety homolog 2 (Drosophila)
chr11_+_117809687 0.647 ENSMUST00000120928.1
ENSMUST00000175737.1
 Syngr2

synaptogyrin 2

chr17_-_48432723 0.630 ENSMUST00000046549.3
 Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr10_-_37138863 0.625 ENSMUST00000092584.5
 Marcks
myristoylated alanine rich protein kinase C substrate
chr7_-_101837776 0.621 ENSMUST00000165052.1
 Inppl1
inositol polyphosphate phosphatase-like 1
chr5_+_92809372 0.593 ENSMUST00000113054.2
 Shroom3
shroom family member 3
chr11_+_117809653 0.586 ENSMUST00000026649.7
ENSMUST00000177131.1
ENSMUST00000132298.1
 Syngr2

Gm20708
synaptogyrin 2

predicted gene 20708
chr2_-_140671400 0.573 ENSMUST00000056760.3
 Flrt3
fibronectin leucine rich transmembrane protein 3
chr10_+_97482350 0.534 ENSMUST00000163448.2
 Dcn
decorin
chr1_+_194619815 0.490 ENSMUST00000027952.5
 Plxna2
plexin A2
chr1_-_126830786 0.419 ENSMUST00000162646.1
 Nckap5
NCK-associated protein 5
chr13_-_58354862 0.394 ENSMUST00000043605.5
 Kif27
kinesin family member 27
chr18_+_11633276 0.389 ENSMUST00000115861.2
 Rbbp8
retinoblastoma binding protein 8
chr2_+_132847719 0.378 ENSMUST00000124836.1
ENSMUST00000154160.1
 Crls1

cardiolipin synthase 1

chr4_+_63558748 0.348 ENSMUST00000077709.4
 6330416G13Rik
RIKEN cDNA 6330416G13 gene
chr7_+_35802593 0.321 ENSMUST00000052454.2
 E130304I02Rik
RIKEN cDNA E130304I02 gene
chrX_+_9885622 0.309 ENSMUST00000067529.2
ENSMUST00000086165.3
 Sytl5

synaptotagmin-like 5

chr1_+_109983737 0.289 ENSMUST00000172005.1
 Cdh7
cadherin 7, type 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 0.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.6 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.4 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.4 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.4 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.1 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) response to cobalt ion(GO:0032025) mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 0.1 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)

Gene overrepresentation in cellular_component category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.8 GO:0034707 chloride channel complex(GO:0034707)
0.2 0.6 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.1 0.2 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)

Gene overrepresentation in molecular_function category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.8 GO:0005254 chloride channel activity(GO:0005254)
0.2 0.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.6 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling