Motif ID: Pou6f2_Pou4f2
Z-value: 0.668


Transcription factors associated with Pou6f2_Pou4f2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Pou4f2 | ENSMUSG00000031688.3 | Pou4f2 |
Pou6f2 | ENSMUSG00000009734.11 | Pou6f2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pou6f2 | mm10_v2_chr13_-_18382041_18382041 | -0.50 | 8.3e-04 | Click! |
Pou4f2 | mm10_v2_chr8_-_78436640_78436649 | 0.03 | 8.7e-01 | Click! |
Top targets:
Showing 1 to 20 of 114 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 43 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 17.3 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
2.5 | 7.4 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
0.8 | 6.3 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
0.2 | 4.2 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.4 | 4.0 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
0.2 | 4.0 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
0.9 | 3.8 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
0.1 | 3.7 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.4 | 2.7 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
0.1 | 2.6 | GO:0003334 | keratinocyte development(GO:0003334) |
0.4 | 2.5 | GO:0019532 | oxalate transport(GO:0019532) |
0.7 | 2.2 | GO:0021759 | globus pallidus development(GO:0021759) |
0.2 | 1.7 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.4 | 1.3 | GO:0061075 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871) |
0.1 | 1.3 | GO:0048853 | forebrain morphogenesis(GO:0048853) |
0.0 | 1.3 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
0.0 | 1.3 | GO:0008585 | female gonad development(GO:0008585) |
0.2 | 1.2 | GO:0060849 | regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
0.4 | 1.1 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
0.4 | 1.1 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
Gene overrepresentation in cellular_component category:
Showing 1 to 19 of 19 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 17.3 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 4.2 | GO:0000792 | heterochromatin(GO:0000792) |
0.0 | 3.8 | GO:0043198 | dendritic shaft(GO:0043198) |
0.2 | 2.7 | GO:0043196 | varicosity(GO:0043196) |
0.0 | 1.8 | GO:0002102 | podosome(GO:0002102) |
0.4 | 1.7 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
0.2 | 1.7 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.1 | 1.3 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
0.2 | 1.2 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.0 | 1.0 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 0.7 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 0.6 | GO:0070382 | exocytic vesicle(GO:0070382) |
0.0 | 0.6 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.0 | 0.6 | GO:0001772 | immunological synapse(GO:0001772) |
0.0 | 0.6 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.1 | 0.5 | GO:0060187 | cell pole(GO:0060187) |
0.0 | 0.5 | GO:0097542 | ciliary tip(GO:0097542) |
0.0 | 0.5 | GO:0031527 | filopodium membrane(GO:0031527) |
0.0 | 0.2 | GO:0071986 | Ragulator complex(GO:0071986) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 28 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 20.9 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
0.4 | 17.3 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.2 | 7.4 | GO:0008009 | chemokine activity(GO:0008009) |
0.6 | 4.3 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
0.2 | 2.7 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.2 | 2.5 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
0.0 | 2.5 | GO:0016779 | nucleotidyltransferase activity(GO:0016779) |
0.2 | 2.2 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
0.2 | 1.7 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.2 | 1.7 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.5 | 1.5 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
0.1 | 1.3 | GO:0070628 | proteasome binding(GO:0070628) |
0.1 | 1.2 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.1 | 1.1 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
0.1 | 1.1 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.0 | 1.0 | GO:0048487 | beta-tubulin binding(GO:0048487) |
0.0 | 0.7 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
0.2 | 0.6 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
0.1 | 0.6 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
0.0 | 0.6 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
Gene overrepresentation in C2:CP category:
Showing 1 to 12 of 12 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 6.3 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
0.1 | 4.7 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 3.8 | PID_LYSOPHOSPHOLIPID_PATHWAY | LPA receptor mediated events |
0.0 | 2.8 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
0.0 | 2.0 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 1.7 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 1.5 | PID_FGF_PATHWAY | FGF signaling pathway |
0.0 | 1.3 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.0 | 1.2 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
0.0 | 1.1 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 0.5 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.0 | 0.5 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 13 of 13 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 20.6 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
0.1 | 2.7 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.0 | 2.5 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.1 | 1.7 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.0 | 1.7 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.0 | 1.6 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
0.0 | 1.5 | REACTOME_SIGNALING_BY_FGFR | Genes involved in Signaling by FGFR |
0.0 | 1.3 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.1 | 1.2 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
0.1 | 1.1 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.1 | 1.1 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
0.1 | 1.0 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
0.0 | 0.6 | REACTOME_REGULATION_OF_KIT_SIGNALING | Genes involved in Regulation of KIT signaling |