Motif ID: Ppard

Z-value: 0.474


Transcription factors associated with Ppard:

Gene SymbolEntrez IDGene Name
Ppard ENSMUSG00000002250.9 Ppard

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ppardmm10_v2_chr17_+_28232723_282327890.182.5e-01Click!


Activity profile for motif Ppard.

activity profile for motif Ppard


Sorted Z-values histogram for motif Ppard

Sorted Z-values for motif Ppard



Network of associatons between targets according to the STRING database.



First level regulatory network of Ppard

PNG image of the network

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Top targets:


Showing 1 to 20 of 68 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_87948666 5.296 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr10_-_13324160 2.105 ENSMUST00000105545.4
 Phactr2
phosphatase and actin regulator 2
chr1_-_120120138 2.044 ENSMUST00000112648.1
ENSMUST00000128408.1
 Dbi

diazepam binding inhibitor

chr3_-_8923796 1.145 ENSMUST00000042148.5
 Mrps28
mitochondrial ribosomal protein S28
chr11_-_4704334 1.124 ENSMUST00000058407.5
 Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr9_-_57262591 1.104 ENSMUST00000034846.5
 1700017B05Rik
RIKEN cDNA 1700017B05 gene
chr5_-_115119277 1.078 ENSMUST00000031524.7
 Acads
acyl-Coenzyme A dehydrogenase, short chain
chr4_+_98546710 1.055 ENSMUST00000102792.3
 Inadl
InaD-like (Drosophila)
chr4_+_118429701 1.048 ENSMUST00000067896.3
 Elovl1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr4_+_98546919 1.012 ENSMUST00000030290.7
 Inadl
InaD-like (Drosophila)
chr4_+_59581563 1.012 ENSMUST00000030078.5
 Hsdl2
hydroxysteroid dehydrogenase like 2
chr17_-_34028044 0.999 ENSMUST00000045467.7
ENSMUST00000114303.3
 H2-Ke6

H2-K region expressed gene 6

chr10_+_93589413 0.898 ENSMUST00000181835.1
 4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr4_+_59581645 0.854 ENSMUST00000107528.1
 Hsdl2
hydroxysteroid dehydrogenase like 2
chr5_-_31697598 0.848 ENSMUST00000031018.7
 Rbks
ribokinase
chr7_+_43444104 0.839 ENSMUST00000004729.3
 Etfb
electron transferring flavoprotein, beta polypeptide
chr5_+_110286306 0.820 ENSMUST00000007296.5
ENSMUST00000112482.1
 Pole

polymerase (DNA directed), epsilon

chr15_+_25773985 0.794 ENSMUST00000125667.1
 Myo10
myosin X
chr18_+_74779190 0.786 ENSMUST00000041053.9
 Acaa2
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)
chr3_-_138131356 0.782 ENSMUST00000029805.8
 Mttp
microsomal triglyceride transfer protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.3 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.4 2.0 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 1.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.1 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.1 1.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 1.0 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 1.0 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 0.8 GO:0045004 DNA replication proofreading(GO:0045004)
0.2 0.8 GO:0006014 D-ribose metabolic process(GO:0006014)
0.2 0.8 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.2 0.8 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.8 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.7 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.7 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.6 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.1 0.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.5 0.5 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.2 0.5 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 2.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 1.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 1.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 0.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)
0.1 0.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.6 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.6 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 5.3 GO:0019841 retinol binding(GO:0019841)
0.7 2.0 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.1 1.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 1.1 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.2 1.0 GO:0070404 NADH binding(GO:0070404)
0.1 1.0 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 0.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.8 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.8 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.8 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.1 0.7 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0009055 electron carrier activity(GO:0009055)
0.2 0.5 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.5 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.3 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID_NETRIN_PATHWAY Netrin-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 1.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.3 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.2 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 1.1 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.0 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.8 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.8 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.8 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 0.6 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.6 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle