Motif ID: Prdm1

Z-value: 1.302


Transcription factors associated with Prdm1:

Gene SymbolEntrez IDGene Name
Prdm1 ENSMUSG00000038151.6 Prdm1



Activity profile for motif Prdm1.

activity profile for motif Prdm1


Sorted Z-values histogram for motif Prdm1

Sorted Z-values for motif Prdm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Prdm1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_137796350 8.358 ENSMUST00000030551.4
 Alpl
alkaline phosphatase, liver/bone/kidney
chr9_-_107668967 7.859 ENSMUST00000177567.1
 Slc38a3
solute carrier family 38, member 3
chr3_+_145758674 7.782 ENSMUST00000029845.8
 Ddah1
dimethylarginine dimethylaminohydrolase 1
chr4_-_154636831 7.614 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
 Prdm16






PR domain containing 16






chr9_+_38718263 6.561 ENSMUST00000001544.5
ENSMUST00000118144.1
 Vwa5a

von Willebrand factor A domain containing 5A

chr15_+_32920723 6.057 ENSMUST00000022871.5
 Sdc2
syndecan 2
chr19_+_36409719 6.029 ENSMUST00000062389.5
 Pcgf5
polycomb group ring finger 5
chr5_+_3343893 5.981 ENSMUST00000165117.1
 Cdk6
cyclin-dependent kinase 6
chr3_-_107760221 5.495 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
 Csf1


colony stimulating factor 1 (macrophage)


chr4_-_96591555 5.435 ENSMUST00000055693.8
 Cyp2j9
cytochrome P450, family 2, subfamily j, polypeptide 9
chr2_-_105399286 5.434 ENSMUST00000006128.6
 Rcn1
reticulocalbin 1
chr8_-_84800024 5.376 ENSMUST00000126806.1
ENSMUST00000076715.6
 Nfix

nuclear factor I/X

chr1_-_156674290 5.213 ENSMUST00000079625.4
 Tor3a
torsin family 3, member A
chr11_-_77894096 4.855 ENSMUST00000017597.4
 Pipox
pipecolic acid oxidase
chr8_-_84800344 4.662 ENSMUST00000099070.3
 Nfix
nuclear factor I/X
chr11_-_82991829 4.261 ENSMUST00000092840.4
ENSMUST00000038211.5
 Slfn9

schlafen 9

chr18_-_41951187 3.984 ENSMUST00000070949.4
 Prelid2
PRELI domain containing 2
chr2_+_116067213 3.961 ENSMUST00000152412.1
 G630016G05Rik
RIKEN cDNA G630016G05 gene
chr1_-_56978534 3.770 ENSMUST00000177282.1
 Satb2
special AT-rich sequence binding protein 2
chr12_+_83987854 3.405 ENSMUST00000021649.7
 Acot2
acyl-CoA thioesterase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 102 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 10.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.1 8.7 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.2 8.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
1.6 7.9 GO:0015817 glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365)
0.7 7.8 GO:0006527 arginine catabolic process(GO:0006527)
0.9 6.0 GO:0044838 cell quiescence(GO:0044838)
1.9 5.6 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
1.8 5.4 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 5.4 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
1.6 4.9 GO:0006553 lysine metabolic process(GO:0006553)
0.9 4.4 GO:0090669 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669)
1.4 4.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.2 3.8 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 3.7 GO:0015914 phospholipid transport(GO:0015914)
0.3 3.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 3.5 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.4 3.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.3 3.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 3.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 3.1 GO:1900027 regulation of ruffle assembly(GO:1900027)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.8 GO:0005925 focal adhesion(GO:0005925)
0.2 8.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 7.7 GO:0016235 aggresome(GO:0016235)
0.4 6.6 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 6.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 6.0 GO:0031519 PcG protein complex(GO:0031519)
1.8 5.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 5.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 5.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 4.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
1.1 4.4 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 3.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 3.3 GO:0005844 polysome(GO:0005844)
1.0 2.9 GO:0005588 collagen type V trimer(GO:0005588)
0.9 2.7 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 2.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 2.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 2.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 2.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 8.7 GO:0033613 activating transcription factor binding(GO:0033613)
2.1 8.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
2.6 7.9 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
1.3 7.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
2.0 6.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 5.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 5.2 GO:0016836 hydro-lyase activity(GO:0016836)
1.2 4.9 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 4.7 GO:0003682 chromatin binding(GO:0003682)
0.0 4.5 GO:0030165 PDZ domain binding(GO:0030165)
0.6 4.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
1.4 4.2 GO:0004454 ketohexokinase activity(GO:0004454)
1.3 4.0 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 3.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 3.6 GO:0005125 cytokine activity(GO:0005125)
0.2 3.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 3.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.4 3.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 3.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) mitogen-activated protein kinase p38 binding(GO:0048273)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.5 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.2 6.4 PID_BARD1_PATHWAY BARD1 signaling events
0.1 6.0 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.5 5.5 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 4.3 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 4.0 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.1 3.1 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 3.0 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 2.9 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.9 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 2.6 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 2.6 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.3 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 2.1 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 1.8 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.5 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.4 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.1 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 1.1 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.9 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 6.1 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 6.0 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 5.1 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 4.4 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 4.2 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 3.3 REACTOME_METABOLISM_OF_CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.1 3.1 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 3.0 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 3.0 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 2.9 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.3 2.7 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 2.6 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 2.4 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 2.1 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.1 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.7 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 1.5 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains