Motif ID: Rorc_Nr1d1
Z-value: 0.466
Transcription factors associated with Rorc_Nr1d1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Nr1d1 | ENSMUSG00000020889.11 | Nr1d1 |
| Rorc | ENSMUSG00000028150.8 | Rorc |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Rorc | mm10_v2_chr3_+_94372794_94372872 | -0.11 | 4.8e-01 | Click! |
| Nr1d1 | mm10_v2_chr11_-_98775333_98775354 | -0.01 | 9.6e-01 | Click! |
Top targets:
Showing 1 to 20 of 111 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 38 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | GO:0007601 | visual perception(GO:0007601) |
| 0.2 | 1.7 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
| 0.4 | 1.2 | GO:0090403 | oxidative stress-induced premature senescence(GO:0090403) |
| 0.2 | 1.1 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.1 | 1.0 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.3 | 0.9 | GO:1902336 | neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) |
| 0.0 | 0.8 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.0 | 0.8 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.1 | 0.7 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.0 | 0.7 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
| 0.2 | 0.5 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
| 0.1 | 0.5 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 0.1 | 0.5 | GO:0043313 | regulation of neutrophil degranulation(GO:0043313) regulation of neutrophil activation(GO:1902563) |
| 0.1 | 0.4 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
| 0.1 | 0.4 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
| 0.1 | 0.4 | GO:0002351 | serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) |
| 0.0 | 0.4 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.1 | 0.3 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.0 | 0.3 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.0 | 0.3 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
Gene overrepresentation in cellular_component category:
Showing 1 to 9 of 9 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.2 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.0 | 1.2 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.0 | 0.4 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 0.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 0.2 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.0 | 0.2 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.0 | 0.1 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 0.1 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 0.1 | GO:0097227 | sperm annulus(GO:0097227) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 27 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.9 | GO:0019841 | retinol binding(GO:0019841) |
| 0.1 | 1.7 | GO:0034979 | NAD-dependent protein deacetylase activity(GO:0034979) |
| 0.1 | 1.2 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.3 | 0.9 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.0 | 0.8 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.7 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 0.7 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.0 | 0.5 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 0.4 | GO:0031752 | D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752) |
| 0.1 | 0.4 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.1 | 0.3 | GO:0004658 | propionyl-CoA carboxylase activity(GO:0004658) |
| 0.1 | 0.3 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.0 | 0.3 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.0 | 0.2 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.0 | 0.2 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.0 | 0.2 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.0 | 0.2 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.0 | 0.2 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 0.2 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
| 0.0 | 0.2 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
Gene overrepresentation in C2:CP category:
Showing 1 to 6 of 6 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.2 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.0 | 1.2 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
| 0.1 | 0.9 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 0.7 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.4 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 0.2 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 11 of 11 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.4 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 1.2 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 0.9 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 0.7 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 0.7 | REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
| 0.0 | 0.4 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 0.4 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.4 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.3 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.0 | 0.2 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.1 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
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