Motif ID: Sox13

Z-value: 0.414


Transcription factors associated with Sox13:

Gene SymbolEntrez IDGene Name
Sox13 ENSMUSG00000070643.5 Sox13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox13mm10_v2_chr1_-_133424377_1334244040.417.2e-03Click!


Activity profile for motif Sox13.

activity profile for motif Sox13


Sorted Z-values histogram for motif Sox13

Sorted Z-values for motif Sox13



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox13

PNG image of the network

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Top targets:


Showing 1 to 20 of 38 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84773381 4.128 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr7_+_96210107 2.644 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chr2_-_36104060 2.370 ENSMUST00000112961.3
ENSMUST00000112966.3
 Lhx6

LIM homeobox protein 6

chr2_+_25180737 2.343 ENSMUST00000104999.2
 Nrarp
Notch-regulated ankyrin repeat protein
chr3_+_34649987 2.039 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr1_+_19103022 1.967 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chr18_+_69593361 1.327 ENSMUST00000114978.2
ENSMUST00000114977.1
 Tcf4

transcription factor 4

chr8_-_11008458 1.294 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2
chr4_-_58499398 1.020 ENSMUST00000107570.1
 Lpar1
lysophosphatidic acid receptor 1
chr12_+_36314160 0.806 ENSMUST00000041407.5
 Sostdc1
sclerostin domain containing 1
chr7_-_132813095 0.805 ENSMUST00000106165.1
 Fam53b
family with sequence similarity 53, member B
chr1_-_93101825 0.521 ENSMUST00000112958.2
 Kif1a
kinesin family member 1A
chr18_+_64887690 0.458 ENSMUST00000163516.1
 Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr15_-_50890396 0.447 ENSMUST00000185183.1
 Trps1
trichorhinophalangeal syndrome I (human)
chr19_-_19001099 0.396 ENSMUST00000040153.8
ENSMUST00000112828.1
 Rorb

RAR-related orphan receptor beta

chr7_-_105787567 0.348 ENSMUST00000144189.1
 Dchs1
dachsous 1 (Drosophila)
chr17_-_68004075 0.273 ENSMUST00000024840.5
 Arhgap28
Rho GTPase activating protein 28
chr14_-_121698417 0.270 ENSMUST00000040700.7
 Dock9
dedicator of cytokinesis 9
chr3_-_141982224 0.262 ENSMUST00000029948.8
 Bmpr1b
bone morphogenetic protein receptor, type 1B
chr1_+_39900883 0.252 ENSMUST00000163854.2
ENSMUST00000168431.1
 Map4k4

mitogen-activated protein kinase kinase kinase kinase 4


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.7 2.6 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.4 2.4 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 2.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.3 2.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 2.0 GO:0030901 midbrain development(GO:0030901)
0.1 1.3 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 1.3 GO:0042118 endothelial cell activation(GO:0042118)
0.3 1.0 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 0.8 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.8 GO:0035411 catenin import into nucleus(GO:0035411)
0.1 0.5 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.4 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.3 GO:0003192 mitral valve formation(GO:0003192) cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)

Gene overrepresentation in cellular_component category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)

Gene overrepresentation in molecular_function category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.0 GO:0035198 miRNA binding(GO:0035198)
0.3 1.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.0 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.8 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.5 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 PID_EPO_PATHWAY EPO signaling pathway
0.0 1.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.0 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 1.3 REACTOME_MYOGENESIS Genes involved in Myogenesis