Motif ID: Sox15

Z-value: 0.417


Transcription factors associated with Sox15:

Gene SymbolEntrez IDGene Name
Sox15 ENSMUSG00000041287.5 Sox15



Activity profile for motif Sox15.

activity profile for motif Sox15


Sorted Z-values histogram for motif Sox15

Sorted Z-values for motif Sox15



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox15

PNG image of the network

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Top targets:


Showing 1 to 20 of 126 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 3.262 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr7_-_49636847 1.915 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr1_-_138842429 1.897 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chrX_+_112604274 1.296 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr2_-_65567465 1.243 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_65567505 1.179 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chrX_+_109095359 1.107 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chrX_+_112600526 0.872 ENSMUST00000113409.1
Zfp711
zinc finger protein 711
chr7_+_82867327 0.869 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr5_+_148265307 0.828 ENSMUST00000110514.1
Mtus2
microtubule associated tumor suppressor candidate 2
chr14_-_48662740 0.799 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr5_+_148265202 0.753 ENSMUST00000110515.2
Mtus2
microtubule associated tumor suppressor candidate 2
chr8_+_108714644 0.709 ENSMUST00000043896.8
Zfhx3
zinc finger homeobox 3
chr10_+_53596936 0.699 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr8_+_45507768 0.694 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr5_+_148265265 0.617 ENSMUST00000071878.5
Mtus2
microtubule associated tumor suppressor candidate 2
chr3_-_33082004 0.616 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr1_+_55406163 0.607 ENSMUST00000042986.8
Plcl1
phospholipase C-like 1
chr3_+_58415689 0.605 ENSMUST00000099090.2
Tsc22d2
TSC22 domain family, member 2
chr18_+_33464163 0.594 ENSMUST00000097634.3
Gm10549
predicted gene 10549

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.5 2.4 GO:0046684 response to pyrethroid(GO:0046684)
0.4 1.9 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 1.9 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 1.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.9 GO:0072697 protein localization to cell cortex(GO:0072697)
0.2 0.8 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.2 0.7 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.6 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.6 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 0.5 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.5 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.5 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.5 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.5 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.5 GO:0000729 DNA double-strand break processing(GO:0000729)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 2.2 GO:0045171 intercellular bridge(GO:0045171)
0.2 1.4 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 0.6 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 0.5 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.4 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 0.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0000812 Swr1 complex(GO:0000812)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.4 GO:0031402 sodium ion binding(GO:0031402)
0.0 2.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.7 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.1 0.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 0.5 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.5 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.9 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.5 PID_BARD1_PATHWAY BARD1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.7 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 0.5 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism