Motif ID: Sox17

Z-value: 0.466


Transcription factors associated with Sox17:

Gene SymbolEntrez IDGene Name
Sox17 ENSMUSG00000025902.7 Sox17

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox17mm10_v2_chr1_-_4496363_4496389-0.241.4e-01Click!


Activity profile for motif Sox17.

activity profile for motif Sox17


Sorted Z-values histogram for motif Sox17

Sorted Z-values for motif Sox17



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox17

PNG image of the network

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Top targets:


Showing 1 to 20 of 84 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 4.408 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr8_-_105471481 2.443 ENSMUST00000014990.6
 Tppp3
tubulin polymerization-promoting protein family member 3
chr6_+_121245903 1.545 ENSMUST00000032198.9
 Usp18
ubiquitin specific peptidase 18
chr1_+_52008210 1.433 ENSMUST00000027277.5
 Stat4
signal transducer and activator of transcription 4
chr2_-_180889660 1.416 ENSMUST00000137629.1
 Gm14342
predicted gene 14342
chr11_-_97775876 0.946 ENSMUST00000107576.1
 1700001P01Rik
RIKEN cDNA 1700001P01 gene
chr19_+_55741810 0.826 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
 Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr2_+_102659213 0.791 ENSMUST00000111213.1
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr14_+_50944499 0.785 ENSMUST00000178092.1
 Pnp
purine-nucleoside phosphorylase
chr4_+_118961578 0.754 ENSMUST00000058651.4
 Lao1
L-amino acid oxidase 1
chr5_-_107597577 0.682 ENSMUST00000100949.3
ENSMUST00000078021.6
 Glmn

glomulin, FKBP associated protein

chr10_+_81821127 0.675 ENSMUST00000099439.3
 Gm4767
predicted gene 4767
chr4_+_41903610 0.665 ENSMUST00000098128.3
 Gm21541
predicted gene, 21541
chr10_+_81661998 0.645 ENSMUST00000105315.2
 Gm10778
predicted gene 10778
chr6_-_148944750 0.638 ENSMUST00000111562.1
ENSMUST00000081956.5
 Fam60a

family with sequence similarity 60, member A

chr4_-_42773993 0.581 ENSMUST00000095114.4
 Ccl21a
chemokine (C-C motif) ligand 21A (serine)
chr11_-_86807624 0.556 ENSMUST00000018569.7
 Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chrX_+_123103546 0.548 ENSMUST00000113348.1
 3110007F17Rik
RIKEN cDNA 3110007F17 gene
chrX_+_123103489 0.529 ENSMUST00000113343.1
 3110007F17Rik
RIKEN cDNA 3110007F17 gene
chr1_+_135729147 0.509 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 4.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 2.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 1.5 GO:0080184 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.1 1.2 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.3 0.8 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.8 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.8 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.8 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.2 0.6 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.4 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1 0.4 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.3 GO:0006553 lysine metabolic process(GO:0006553)
0.1 0.3 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) transforming growth factor-beta secretion(GO:0038044) blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.2 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.2 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.4 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.5 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.1 0.2 GO:0071953 fibrinogen complex(GO:0005577) elastic fiber(GO:0071953)
0.1 0.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.4 1.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 1.2 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.3 0.8 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 0.8 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.8 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.4 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0090079 translation repressor activity, nucleic acid binding(GO:0000900) translation regulator activity, nucleic acid binding(GO:0090079)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.8 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.5 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.1 0.8 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.8 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.4 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters