Z-value: 1.253
Transcription factors associated with Srf:
Activity-expression correlation:
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Showing 1 to 20 of 122 entries
Gene overrepresentation in biological_process category:
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Showing 1 to 20 of 45 entries
Log-likelihood per target Total log-likelihood Term Description
4.1
12.4
GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
2.0
12.0
GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
2.7
10.9
GO:0030091 protein repair(GO:0030091)
0.7
7.1
GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.7
6.5
GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.1
6.2
GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1
5.0
GO:0071277 cellular response to calcium ion(GO:0071277)
0.3
4.7
GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.9
4.4
GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.6
4.1
GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1
3.8
GO:0070527 platelet aggregation(GO:0070527)
0.2
3.3
GO:0035994 response to muscle stretch(GO:0035994)
1.0
3.0
GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0
2.3
GO:0048706 embryonic skeletal system development(GO:0048706)
0.2
2.2
GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1
2.1
GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.5
2.0
GO:0060025 regulation of synaptic activity(GO:0060025)
0.3
2.0
GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0
1.9
GO:0051290 protein heterotetramerization(GO:0051290)
0.4
1.8
GO:0050689 negative regulation of interferon-beta biosynthetic process(GO:0045358) negative regulation of defense response to virus by host(GO:0050689)
Gene overrepresentation in cellular_component category:
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Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihood Term Description
0.0
6.1
GO:0000139 Golgi membrane(GO:0000139)
0.2
4.7
GO:0005680 anaphase-promoting complex(GO:0005680)
0.7
4.4
GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.6
3.3
GO:0035976 AP1 complex(GO:0035976)
0.6
3.0
GO:0033093 Weibel-Palade body(GO:0033093)
0.1
2.2
GO:0000124 SAGA complex(GO:0000124)
0.1
2.1
GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0
2.0
GO:0043034 costamere(GO:0043034)
0.0
1.9
GO:0000794 condensed nuclear chromosome(GO:0000794)
0.5
1.8
GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1
1.7
GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1
1.5
GO:0070938 contractile ring(GO:0070938)
0.1
1.5
GO:0016460 myosin II complex(GO:0016460)
0.3
1.3
GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.0
1.2
GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0
1.1
GO:0030018 Z disc(GO:0030018)
0.1
1.0
GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0
1.0
GO:0090544 BAF-type complex(GO:0090544)
0.0
0.9
GO:0005902 microvillus(GO:0005902)
0.1
0.8
GO:1990907 beta-catenin-TCF complex(GO:1990907)
Gene overrepresentation in molecular_function category:
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Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihood Term Description
3.1
12.4
GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0
11.1
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
1.8
10.9
GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1
10.1
GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1
7.1
GO:0002039 p53 binding(GO:0002039)
0.1
4.4
GO:0035064 methylated histone binding(GO:0035064)
0.1
3.3
GO:0070412 R-SMAD binding(GO:0070412)
0.0
3.0
GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0
2.7
GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1
2.6
GO:0008307 structural constituent of muscle(GO:0008307)
0.1
2.2
GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0
2.1
GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.3
1.9
GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.4
1.8
GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2
1.8
GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3
1.7
GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2
1.5
GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1
1.5
GO:0032036 myosin heavy chain binding(GO:0032036)
0.1
1.5
GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1
1.4
GO:0071837 HMG box domain binding(GO:0071837)
Gene overrepresentation in C2:CP category:
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Showing 1 to 17 of 17 entries
Gene overrepresentation in C2:CP:REACTOME category:
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Showing 1 to 13 of 13 entries
