Motif ID: Taf1

Z-value: 2.847


Transcription factors associated with Taf1:

Gene SymbolEntrez IDGene Name
Taf1 ENSMUSG00000031314.11 Taf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Taf1mm10_v2_chrX_+_101532734_1015327770.773.6e-09Click!


Activity profile for motif Taf1.

activity profile for motif Taf1


Sorted Z-values histogram for motif Taf1

Sorted Z-values for motif Taf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Taf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_103483205 10.409 ENSMUST00000127786.2
 Xist
inactive X specific transcripts
chr3_-_84220853 10.054 ENSMUST00000154152.1
ENSMUST00000107693.2
ENSMUST00000107695.2
 Trim2


tripartite motif-containing 2


chr7_+_59228743 8.941 ENSMUST00000107537.1
 Ube3a
ubiquitin protein ligase E3A
chr5_-_123749393 8.707 ENSMUST00000057795.5
ENSMUST00000111515.1
ENSMUST00000182309.1
 Rsrc2


arginine/serine-rich coiled-coil 2


chrX_-_73966329 8.318 ENSMUST00000114372.2
ENSMUST00000033761.6
 Hcfc1

host cell factor C1

chr5_+_23434435 8.263 ENSMUST00000094962.2
ENSMUST00000115128.1
 Kmt2e

lysine (K)-specific methyltransferase 2E

chr5_-_123749371 7.902 ENSMUST00000182955.1
ENSMUST00000182489.1
ENSMUST00000050827.7
 Rsrc2


arginine/serine-rich coiled-coil 2


chr7_-_98656530 7.246 ENSMUST00000038359.4
 2210018M11Rik
RIKEN cDNA 2210018M11 gene
chr8_-_111259192 7.194 ENSMUST00000169020.1
ENSMUST00000003404.8
 Glg1

golgi apparatus protein 1

chr19_+_46761578 6.915 ENSMUST00000077666.4
ENSMUST00000099373.4
 Cnnm2

cyclin M2

chr6_-_18514802 6.832 ENSMUST00000090601.5
 Cttnbp2
cortactin binding protein 2
chr18_-_6241470 6.582 ENSMUST00000163210.1
 Kif5b
kinesin family member 5B
chr13_+_96542727 6.488 ENSMUST00000077672.4
ENSMUST00000109444.2
 Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr2_-_180709985 6.207 ENSMUST00000103057.1
ENSMUST00000103055.1
 Dido1

death inducer-obliterator 1

chr6_+_92092369 6.177 ENSMUST00000113463.1
 Nr2c2
nuclear receptor subfamily 2, group C, member 2
chr5_-_113015473 6.169 ENSMUST00000065167.4
 Adrbk2
adrenergic receptor kinase, beta 2
chr6_+_38433913 5.920 ENSMUST00000160583.1
 Ubn2
ubinuclein 2
chr18_+_34220890 5.728 ENSMUST00000171187.1
 Apc
adenomatosis polyposis coli
chr12_+_71015966 5.685 ENSMUST00000046305.5
 Arid4a
AT rich interactive domain 4A (RBP1-like)
chr1_-_119837613 5.680 ENSMUST00000064091.5
 Ptpn4
protein tyrosine phosphatase, non-receptor type 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 460 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.6 17.9 GO:1904908 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
2.4 11.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.7 11.6 GO:0090169 regulation of spindle assembly(GO:0090169)
0.8 11.2 GO:0060009 Sertoli cell development(GO:0060009)
1.1 11.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.3 11.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 10.8 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.7 10.6 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
3.5 10.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
3.4 10.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
1.4 10.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.4 10.0 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.7 9.8 GO:0060363 cranial suture morphogenesis(GO:0060363)
2.4 9.4 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.3 9.2 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.2 9.1 GO:0016574 histone ubiquitination(GO:0016574)
0.5 9.0 GO:0015693 magnesium ion transport(GO:0015693)
2.2 8.9 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.9 8.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.3 8.9 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 207 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.5 13.9 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.1 13.3 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 13.2 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.2 12.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 11.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.6 11.8 GO:0035253 ciliary rootlet(GO:0035253)
0.1 11.6 GO:0005802 trans-Golgi network(GO:0005802)
1.1 11.5 GO:0000805 X chromosome(GO:0000805)
0.2 11.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 10.4 GO:0005768 endosome(GO:0005768)
0.0 9.9 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
1.2 9.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.4 9.8 GO:0005797 Golgi medial cisterna(GO:0005797)
1.2 9.7 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 9.6 GO:0030426 growth cone(GO:0030426)
0.4 9.5 GO:0000242 pericentriolar material(GO:0000242)
0.1 9.5 GO:0036064 ciliary basal body(GO:0036064)
0.7 9.0 GO:1990635 proximal dendrite(GO:1990635)
0.1 9.0 GO:0031526 brush border membrane(GO:0031526)
2.2 8.6 GO:0044307 dendritic branch(GO:0044307)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 261 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 29.8 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 24.5 GO:0008270 zinc ion binding(GO:0008270)
0.1 22.1 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 21.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 18.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 18.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 16.8 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.7 14.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
2.0 14.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3 14.0 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
2.0 13.9 GO:0015616 DNA translocase activity(GO:0015616)
1.6 13.0 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 12.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
1.4 12.4 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.6 12.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 11.5 GO:0005509 calcium ion binding(GO:0005509)
0.1 11.2 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
1.7 10.2 GO:0097001 ceramide binding(GO:0097001)
0.2 10.2 GO:0017022 myosin binding(GO:0017022)
0.2 10.0 GO:0035064 methylated histone binding(GO:0035064)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 17.9 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.3 15.7 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.5 13.6 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 12.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.2 12.2 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.3 11.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.5 11.2 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.2 8.8 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.3 8.0 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 6.8 PID_INSULIN_PATHWAY Insulin Pathway
0.4 6.2 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 5.5 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3 5.0 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 4.8 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 4.2 PID_RHOA_PATHWAY RhoA signaling pathway
0.2 4.1 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 3.5 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 3.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 3.2 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 3.2 PID_TNF_PATHWAY TNF receptor signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 18.7 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras
0.4 17.9 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.2 14.2 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.5 14.0 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.6 13.6 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.6 11.7 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.4 10.7 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.3 10.1 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 9.9 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.4 9.8 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.3 9.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 9.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 7.5 REACTOME_RNA_POL_III_TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.2 7.2 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 5.8 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.3 5.6 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 5.5 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.2 5.2 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.4 5.1 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 4.3 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases