Motif ID: Thrb

Z-value: 0.448


Transcription factors associated with Thrb:

Gene SymbolEntrez IDGene Name
Thrb ENSMUSG00000021779.10 Thrb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Thrbmm10_v2_chr14_+_17660956_17660963-0.105.4e-01Click!


Activity profile for motif Thrb.

activity profile for motif Thrb


Sorted Z-values histogram for motif Thrb

Sorted Z-values for motif Thrb



Network of associatons between targets according to the STRING database.



First level regulatory network of Thrb

PNG image of the network

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Top targets:


Showing 1 to 20 of 36 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_107668967 2.284 ENSMUST00000177567.1
Slc38a3
solute carrier family 38, member 3
chr12_+_108334341 2.130 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr2_-_25470031 1.760 ENSMUST00000114251.1
Ptgds
prostaglandin D2 synthase (brain)
chr2_-_105399286 1.582 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr12_+_112620030 1.556 ENSMUST00000180015.1
ENSMUST00000021726.6
Adssl1

adenylosuccinate synthetase like 1

chr2_-_25469742 1.492 ENSMUST00000114259.2
ENSMUST00000015234.6
Ptgds

prostaglandin D2 synthase (brain)

chr3_-_36475688 1.381 ENSMUST00000029266.8
Anxa5
annexin A5
chr3_+_14863495 1.199 ENSMUST00000029076.4
Car3
carbonic anhydrase 3
chr11_-_115612491 1.150 ENSMUST00000106507.2
Mif4gd
MIF4G domain containing
chr5_-_92278155 1.047 ENSMUST00000159345.1
ENSMUST00000113102.3
Naaa

N-acylethanolamine acid amidase

chr3_-_79842662 0.996 ENSMUST00000029568.1
Tmem144
transmembrane protein 144
chr5_-_111761697 0.903 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
E130006D01Rik


RIKEN cDNA E130006D01 gene


chr11_+_109485606 0.860 ENSMUST00000106697.1
Arsg
arylsulfatase G
chr16_+_32419696 0.734 ENSMUST00000014220.8
ENSMUST00000080316.7
Tctex1d2

Tctex1 domain containing 2

chr3_+_67374116 0.550 ENSMUST00000061322.8
Mlf1
myeloid leukemia factor 1
chr3_+_67374091 0.544 ENSMUST00000077916.5
Mlf1
myeloid leukemia factor 1
chr16_+_36934976 0.503 ENSMUST00000023531.8
Hcls1
hematopoietic cell specific Lyn substrate 1
chr1_-_137969213 0.486 ENSMUST00000182680.1
ENSMUST00000182424.1
Gm26936

predicted gene, 26936

chr9_+_102626278 0.423 ENSMUST00000038673.7
Anapc13
anaphase promoting complex subunit 13
chr15_-_103251465 0.356 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
Nfe2




nuclear factor, erythroid derived 2





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 3.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.5 2.3 GO:0015817 glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365)
0.2 2.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.5 1.6 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.3 1.4 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 1.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 1.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 1.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.4 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.4 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.3 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.4 GO:0014704 intercalated disc(GO:0014704)
0.0 1.1 GO:0097546 ciliary base(GO:0097546)
0.1 0.7 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in molecular_function category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 3.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.8 2.3 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.1 2.1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.6 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.1 1.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.2 GO:0016151 nickel cation binding(GO:0016151)
0.1 0.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.9 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.3 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.1 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 2.1 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 1.6 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.9 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint