Motif ID: Ubp1

Z-value: 0.722


Transcription factors associated with Ubp1:

Gene SymbolEntrez IDGene Name
Ubp1 ENSMUSG00000009741.8 Ubp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ubp1mm10_v2_chr9_+_113930934_113930987-0.231.5e-01Click!


Activity profile for motif Ubp1.

activity profile for motif Ubp1


Sorted Z-values histogram for motif Ubp1

Sorted Z-values for motif Ubp1



Network of associatons between targets according to the STRING database.



First level regulatory network of Ubp1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 2.882 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr1_-_75278345 1.838 ENSMUST00000039534.4
 Resp18
regulated endocrine-specific protein 18
chr14_-_37098211 1.711 ENSMUST00000022337.9
 Cdhr1
cadherin-related family member 1
chr10_-_128549125 1.709 ENSMUST00000177163.1
ENSMUST00000176683.1
ENSMUST00000176010.1
 Rpl41


ribosomal protein L41


chr3_+_106113229 1.661 ENSMUST00000079132.5
ENSMUST00000139086.1
 Chia

chitinase, acidic

chr12_+_113152012 1.521 ENSMUST00000006523.7
 Crip1
cysteine-rich protein 1 (intestinal)
chr12_-_10900296 1.501 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr8_+_94179089 1.393 ENSMUST00000034215.6
 Mt1
metallothionein 1
chr2_-_151973387 1.387 ENSMUST00000109863.1
 Fam110a
family with sequence similarity 110, member A
chr6_+_47244359 1.385 ENSMUST00000060839.6
 Cntnap2
contactin associated protein-like 2
chr10_-_128549102 1.340 ENSMUST00000176906.1
 Rpl41
ribosomal protein L41
chr5_+_90772435 1.314 ENSMUST00000031320.6
 Pf4
platelet factor 4
chr7_+_107567445 1.288 ENSMUST00000120990.1
 Olfml1
olfactomedin-like 1
chr1_+_172499948 1.221 ENSMUST00000111230.1
 Tagln2
transgelin 2
chr3_+_67892189 1.194 ENSMUST00000063263.3
 Iqcj
IQ motif containing J
chr10_+_14523062 1.182 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chrX_+_73483602 1.182 ENSMUST00000033741.8
ENSMUST00000169489.1
 Bgn

biglycan

chr17_-_50094277 1.114 ENSMUST00000113195.1
 Rftn1
raftlin lipid raft linker 1
chr17_+_29090969 1.100 ENSMUST00000119901.1
 Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr5_-_44799643 1.099 ENSMUST00000070748.5
 Ldb2
LIM domain binding 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 257 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.5 2.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 2.6 GO:0071493 cellular response to UV-B(GO:0071493)
0.3 1.9 GO:0032439 endosome localization(GO:0032439)
0.3 1.8 GO:0071294 cellular response to zinc ion(GO:0071294)
0.3 1.7 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 1.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.3 1.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.3 1.4 GO:0051311 spindle assembly involved in female meiosis(GO:0007056) meiotic metaphase plate congression(GO:0051311)
0.3 1.4 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 1.4 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 1.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.3 1.3 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347) negative regulation of cytolysis(GO:0045918)
0.1 1.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4 1.1 GO:0016115 terpenoid catabolic process(GO:0016115)
0.3 1.1 GO:0030091 protein repair(GO:0030091)
0.1 1.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 1.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 1.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 120 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 1.9 GO:0045179 apical cortex(GO:0045179)
0.0 1.9 GO:0015934 large ribosomal subunit(GO:0015934)
0.4 1.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 1.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.7 GO:0005581 collagen trimer(GO:0005581)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.3 GO:0072687 meiotic spindle(GO:0072687)
0.1 1.3 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 1.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.2 GO:0016459 myosin complex(GO:0016459)
0.4 1.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 1.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.1 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 1.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 1.0 GO:0030061 mitochondrial crista(GO:0030061)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 167 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 2.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 2.0 GO:0070888 E-box binding(GO:0070888)
0.0 2.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.9 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 1.8 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 1.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 1.5 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 1.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 1.4 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 1.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.3 1.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 1.3 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 1.3 GO:0005507 copper ion binding(GO:0005507)
0.0 1.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.4 1.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.7 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 2.2 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 1.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.8 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.2 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 1.1 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.1 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.0 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 1.0 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 1.0 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.8 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.7 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.7 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.7 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.7 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 0.7 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.6 PID_ALK1_PATHWAY ALK1 signaling events
0.1 0.5 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.9 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 4.3 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 3.3 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 2.3 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 1.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.2 1.3 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 1.2 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.2 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.0 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 0.9 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.9 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 0.8 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.8 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.2 0.7 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.7 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.7 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.7 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.6 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.6 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling