Motif ID: Zfp105

Z-value: 0.461


Transcription factors associated with Zfp105:

Gene SymbolEntrez IDGene Name
Zfp105 ENSMUSG00000057895.5 Zfp105

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp105mm10_v2_chr9_+_122923050_1229230990.212.0e-01Click!


Activity profile for motif Zfp105.

activity profile for motif Zfp105


Sorted Z-values histogram for motif Zfp105

Sorted Z-values for motif Zfp105



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp105

PNG image of the network

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Top targets:


Showing 1 to 20 of 44 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_144892813 4.677 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr5_+_17574268 3.029 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr8_+_128359065 2.420 ENSMUST00000026917.8
 Nrp1
neuropilin 1
chr8_-_84773381 2.116 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr5_+_13399309 1.942 ENSMUST00000030714.7
ENSMUST00000141968.1
 Sema3a

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

chr1_-_190170671 1.627 ENSMUST00000175916.1
 Prox1
prospero-related homeobox 1
chr8_-_11008458 1.396 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2
chr18_+_69344503 1.238 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr5_-_111761697 1.134 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
 E130006D01Rik


RIKEN cDNA E130006D01 gene


chr13_-_67609617 1.102 ENSMUST00000138725.1
 AA987161
expressed sequence AA987161
chr13_-_67609667 1.006 ENSMUST00000012873.8
 AA987161
expressed sequence AA987161
chr12_-_90738438 0.870 ENSMUST00000082432.3
 Dio2
deiodinase, iodothyronine, type II
chr2_-_177267036 0.784 ENSMUST00000108963.1
 Gm14409
predicted gene 14409
chr4_+_11704439 0.762 ENSMUST00000108304.2
 Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr8_-_64205970 0.655 ENSMUST00000066166.4
 Tll1
tolloid-like
chr18_+_37484955 0.631 ENSMUST00000053856.4
 Pcdhb17
protocadherin beta 17
chr6_-_142964404 0.556 ENSMUST00000032421.3
 St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr2_-_91931774 0.540 ENSMUST00000069423.6
 Mdk
midkine
chr5_+_19907502 0.537 ENSMUST00000101558.3
 Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr18_+_30272747 0.487 ENSMUST00000115812.3
ENSMUST00000115811.1
ENSMUST00000091978.5
 Pik3c3


phosphoinositide-3-kinase, class 3



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 7.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.4 4.7 GO:0042572 retinol metabolic process(GO:0042572)
0.1 2.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.5 1.6 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 1.4 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 1.2 GO:0042118 endothelial cell activation(GO:0042118)
0.2 0.9 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.1 0.8 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.6 GO:0034605 cellular response to heat(GO:0034605)
0.2 0.5 GO:0030421 defecation(GO:0030421)
0.2 0.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.5 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.4 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.2 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.4 GO:0097443 sorting endosome(GO:0097443)
0.0 0.8 GO:0051233 spindle midzone(GO:0051233)
0.2 0.5 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.4 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)

Gene overrepresentation in molecular_function category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.0 GO:0038191 neuropilin binding(GO:0038191)
0.7 4.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.5 2.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 1.6 GO:0050693 LBD domain binding(GO:0050693)
0.0 1.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.3 1.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.1 0.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.5 GO:0035004 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 0.5 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)

Gene overrepresentation in C2:CP category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.7 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 2.4 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 1.4 PID_EPO_PATHWAY EPO signaling pathway
0.0 1.2 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 4.4 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.4 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 1.2 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 0.9 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.7 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels