Motif ID: Zfp148

Z-value: 1.127


Transcription factors associated with Zfp148:

Gene SymbolEntrez IDGene Name
Zfp148 ENSMUSG00000022811.10 Zfp148

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp148mm10_v2_chr16_+_33380765_333807870.846.1e-12Click!


Activity profile for motif Zfp148.

activity profile for motif Zfp148


Sorted Z-values histogram for motif Zfp148

Sorted Z-values for motif Zfp148



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp148

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_103510874 12.071 ENSMUST00000066905.6
Chl1
cell adhesion molecule with homology to L1CAM
chr9_-_98032983 11.651 ENSMUST00000162295.1
Clstn2
calsyntenin 2
chr5_+_17574726 10.883 ENSMUST00000169603.1
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr9_-_40455670 10.326 ENSMUST00000165104.1
ENSMUST00000045682.5
Gramd1b

GRAM domain containing 1B

chr5_+_17574268 10.016 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr11_-_102897123 7.947 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr8_+_70493156 7.140 ENSMUST00000008032.7
Crlf1
cytokine receptor-like factor 1
chr10_+_13966268 6.849 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr10_+_106470281 5.205 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr11_-_102897146 5.151 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr11_+_3332426 4.316 ENSMUST00000136474.1
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr4_-_133498538 4.089 ENSMUST00000125541.1
Trnp1
TMF1-regulated nuclear protein 1
chr2_-_104409992 3.922 ENSMUST00000149466.1
ENSMUST00000139015.1
D430041D05Rik

RIKEN cDNA D430041D05 gene

chr2_+_32741452 3.658 ENSMUST00000131101.1
Sh2d3c
SH2 domain containing 3C
chr2_+_107290590 3.490 ENSMUST00000037012.2
Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr2_-_104410334 3.445 ENSMUST00000089726.3
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr18_+_64340225 3.320 ENSMUST00000175965.2
ENSMUST00000115145.3
Onecut2

one cut domain, family member 2

chr4_-_149774238 3.316 ENSMUST00000105686.2
Slc25a33
solute carrier family 25, member 33
chr8_+_84723003 3.208 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chr11_+_105589970 3.138 ENSMUST00000168598.1
ENSMUST00000100330.3
Tanc2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 151 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.5 20.9 GO:0003350 pulmonary myocardium development(GO:0003350)
0.3 13.8 GO:0035640 exploration behavior(GO:0035640)
1.9 13.1 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.1 12.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.7 7.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
1.2 7.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
1.2 6.2 GO:0060178 regulation of exocyst localization(GO:0060178)
1.9 5.7 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.9 5.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.3 5.2 GO:1990403 embryonic brain development(GO:1990403)
1.3 5.0 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 4.4 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.6 4.3 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 4.1 GO:0021696 cerebellar cortex morphogenesis(GO:0021696)
1.3 4.0 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 3.9 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.2 3.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 3.8 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.7 3.4 GO:0046113 nucleobase catabolic process(GO:0046113)
0.8 3.3 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 77 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 16.0 GO:0045211 postsynaptic membrane(GO:0045211)
3.3 13.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 7.9 GO:0031225 anchored component of membrane(GO:0031225)
2.4 7.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 5.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.3 5.7 GO:0032279 asymmetric synapse(GO:0032279)
0.2 5.7 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 5.2 GO:0035869 ciliary transition zone(GO:0035869)
0.1 5.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 4.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 4.4 GO:0030118 clathrin coat(GO:0030118)
0.4 4.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 4.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 4.0 GO:0009986 cell surface(GO:0009986)
0.1 3.3 GO:0031901 early endosome membrane(GO:0031901)
0.5 3.1 GO:0008091 spectrin(GO:0008091)
0.1 3.0 GO:0031430 M band(GO:0031430)
0.2 2.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 2.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 2.9 GO:0001891 phagocytic cup(GO:0001891)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 115 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 21.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 12.1 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 11.9 GO:0002020 protease binding(GO:0002020)
0.1 10.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 9.2 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.1 7.4 GO:0051082 unfolded protein binding(GO:0051082)
0.1 7.2 GO:0030507 spectrin binding(GO:0030507)
1.0 7.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
1.1 5.7 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.5 5.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.6 5.0 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
1.4 4.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.8 4.0 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.8 4.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 4.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 3.5 GO:0030955 potassium ion binding(GO:0030955)
0.1 3.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 3.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 3.1 GO:0017048 Rho GTPase binding(GO:0017048)
0.3 3.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 22.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 8.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 5.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.3 5.2 ST_STAT3_PATHWAY STAT3 Pathway
0.0 3.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 3.4 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 2.9 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 2.6 PID_SHP2_PATHWAY SHP2 signaling
0.0 2.5 PID_LKB1_PATHWAY LKB1 signaling events
0.1 2.1 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 2.1 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 1.6 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 1.5 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.3 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.2 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 1.1 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.1 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.1 PID_INSULIN_PATHWAY Insulin Pathway
0.0 1.1 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 1.0 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 13.8 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.3 6.4 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 6.0 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.3 5.6 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.4 5.0 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.1 5.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 4.3 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 4.2 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 2.5 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 2.2 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 2.2 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 2.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 2.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.0 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.7 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.7 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.3 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.1 1.2 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.2 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions