Motif ID: Zfp263

Z-value: 0.941


Transcription factors associated with Zfp263:

Gene SymbolEntrez IDGene Name
Zfp263 ENSMUSG00000022529.5 Zfp263

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp263mm10_v2_chr16_+_3744089_37441450.038.5e-01Click!


Activity profile for motif Zfp263.

activity profile for motif Zfp263


Sorted Z-values histogram for motif Zfp263

Sorted Z-values for motif Zfp263



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp263

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_12385769 9.780 ENSMUST00000080795.8
 Gm5607
predicted gene 5607
chr11_+_105292637 8.066 ENSMUST00000100335.3
ENSMUST00000021038.4
 Mrc2

mannose receptor, C type 2

chr6_-_6882068 8.005 ENSMUST00000142635.1
ENSMUST00000052609.8
 Dlx5

distal-less homeobox 5

chr18_+_34861200 6.943 ENSMUST00000165033.1
 Egr1
early growth response 1
chr2_-_71546745 5.888 ENSMUST00000024159.6
 Dlx2
distal-less homeobox 2
chr3_+_83766300 5.061 ENSMUST00000029625.7
 Sfrp2
secreted frizzled-related protein 2
chr11_+_112782182 4.896 ENSMUST00000000579.2
 Sox9
SRY-box containing gene 9
chr1_-_172297989 4.736 ENSMUST00000085913.4
ENSMUST00000097464.2
ENSMUST00000137679.1
 Atp1a2


ATPase, Na+/K+ transporting, alpha 2 polypeptide


chr2_-_36105271 4.095 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
 Lhx6


LIM homeobox protein 6


chr2_+_31640037 4.076 ENSMUST00000113470.2
 Prdm12
PR domain containing 12
chr1_-_133424377 4.056 ENSMUST00000153799.1
 Sox13
SRY-box containing gene 13
chrX_+_100730178 3.609 ENSMUST00000113744.1
 Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr9_-_107667375 3.433 ENSMUST00000010208.8
 Slc38a3
solute carrier family 38, member 3
chr6_+_6863269 3.342 ENSMUST00000160937.2
ENSMUST00000171311.1
 Dlx6

distal-less homeobox 6

chr14_+_46882854 3.051 ENSMUST00000022386.8
ENSMUST00000100672.3
 Samd4

sterile alpha motif domain containing 4

chr13_-_60177357 3.031 ENSMUST00000065086.4
 Gas1
growth arrest specific 1
chr9_+_23223076 3.026 ENSMUST00000071982.5
 Bmper
BMP-binding endothelial regulator
chrX_+_100729917 2.769 ENSMUST00000019503.7
 Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr10_-_87493651 2.754 ENSMUST00000020243.7
 Ascl1
achaete-scute complex homolog 1 (Drosophila)
chr15_-_103366763 2.732 ENSMUST00000023128.6
 Itga5
integrin alpha 5 (fibronectin receptor alpha)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 188 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.6 10.8 GO:0060166 olfactory pit development(GO:0060166)
3.1 9.3 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.5 8.2 GO:0030574 collagen catabolic process(GO:0030574)
0.3 6.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.6 6.4 GO:0090527 actin filament reorganization(GO:0090527)
2.0 5.9 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
1.7 5.1 GO:1904956 dermatome development(GO:0061054) sclerotome development(GO:0061056) regulation of dermatome development(GO:0061183) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
2.4 4.9 GO:0072034 renal vesicle induction(GO:0072034)
1.6 4.7 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.3 4.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 4.6 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.3 4.4 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.8 4.1 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.7 4.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.3 4.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 4.0 GO:0070206 protein trimerization(GO:0070206)
0.7 3.4 GO:0015817 glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365)
0.1 3.2 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 3.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.3 3.0 GO:0042473 outer ear morphogenesis(GO:0042473)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 83 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.2 GO:0005925 focal adhesion(GO:0005925)
0.0 5.7 GO:0000790 nuclear chromatin(GO:0000790)
0.0 5.5 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 5.2 GO:0005802 trans-Golgi network(GO:0005802)
0.7 5.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 4.7 GO:0000139 Golgi membrane(GO:0000139)
0.9 4.6 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 4.1 GO:0005884 actin filament(GO:0005884)
0.1 3.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.8 GO:0001650 fibrillar center(GO:0001650)
0.4 2.7 GO:0097422 tubular endosome(GO:0097422)
0.1 2.7 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 2.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 2.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 2.1 GO:0005657 replication fork(GO:0005657)
0.0 2.1 GO:0005903 brush border(GO:0005903)
0.2 1.9 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.9 GO:0034704 calcium channel complex(GO:0034704)
0.4 1.8 GO:0036449 microtubule minus-end(GO:0036449)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 137 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.4 GO:0005518 collagen binding(GO:0005518)
0.2 7.9 GO:0071837 HMG box domain binding(GO:0071837)
1.7 6.9 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.5 6.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.8 6.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.6 5.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.6 5.0 GO:1990239 steroid hormone binding(GO:1990239)
0.4 4.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.3 4.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.6 3.9 GO:0034056 estrogen response element binding(GO:0034056)
0.9 3.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 3.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 3.6 GO:0008307 structural constituent of muscle(GO:0008307)
1.1 3.4 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.1 3.1 GO:0070888 E-box binding(GO:0070888)
0.5 2.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 2.8 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 2.8 GO:0008201 heparin binding(GO:0008201)
0.4 2.6 GO:0034452 dynactin binding(GO:0034452)
0.2 2.4 GO:0030371 translation repressor activity(GO:0030371)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 11.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 7.8 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.3 7.3 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.2 5.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 4.6 NABA_COLLAGENS Genes encoding collagen proteins
0.1 4.5 PID_PLK1_PATHWAY PLK1 signaling events
0.2 4.2 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 3.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 3.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.9 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 2.6 PID_FOXO_PATHWAY FoxO family signaling
0.1 2.5 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.4 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 2.2 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 2.2 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 2.0 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 1.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 1.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 1.7 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.8 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 7.8 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 6.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 5.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 3.4 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 3.3 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 3.1 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.7 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.0 2.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.1 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 1.8 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 1.8 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 1.7 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.7 REACTOME_DAG_AND_IP3_SIGNALING Genes involved in DAG and IP3 signaling
0.1 1.6 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 1.4 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.4 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.4 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.1 1.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis