Motif ID: Zfp384

Z-value: 1.279


Transcription factors associated with Zfp384:

Gene SymbolEntrez IDGene Name
Zfp384 ENSMUSG00000038346.12 Zfp384

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp384mm10_v2_chr6_+_125009261_125009317-0.324.1e-02Click!


Activity profile for motif Zfp384.

activity profile for motif Zfp384


Sorted Z-values histogram for motif Zfp384

Sorted Z-values for motif Zfp384



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp384

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 10.453 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr13_+_94875600 6.235 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chrX_-_60893430 5.483 ENSMUST00000135107.2
 Sox3
SRY-box containing gene 3
chr17_+_85620816 5.428 ENSMUST00000175898.2
 Six3
sine oculis-related homeobox 3
chr4_-_143299498 5.159 ENSMUST00000030317.7
 Pdpn
podoplanin
chr3_-_145649970 5.102 ENSMUST00000029846.3
 Cyr61
cysteine rich protein 61
chr5_-_135251209 4.856 ENSMUST00000062572.2
 Fzd9
frizzled homolog 9 (Drosophila)
chr6_-_23248264 4.688 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr16_-_22161450 4.641 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr18_-_74961252 4.600 ENSMUST00000066532.4
 Lipg
lipase, endothelial
chr2_+_25218741 4.491 ENSMUST00000028346.3
 Fam166a
family with sequence similarity 166, member A
chr7_-_34812677 4.380 ENSMUST00000078686.6
 Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr6_+_8948608 4.180 ENSMUST00000160300.1
 Nxph1
neurexophilin 1
chr1_+_90203980 4.160 ENSMUST00000065587.4
ENSMUST00000159654.1
 Ackr3

atypical chemokine receptor 3

chr13_-_53286052 4.059 ENSMUST00000021918.8
 Ror2
receptor tyrosine kinase-like orphan receptor 2
chr4_-_143299463 4.052 ENSMUST00000119654.1
 Pdpn
podoplanin
chr2_+_70562854 3.949 ENSMUST00000130998.1
 Gad1
glutamate decarboxylase 1
chr12_+_118846329 3.882 ENSMUST00000063918.2
 Sp8
trans-acting transcription factor 8
chr18_-_74207771 3.868 ENSMUST00000040188.8
ENSMUST00000177604.1
 Ska1

spindle and kinetochore associated complex subunit 1

chr16_-_26989974 3.801 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 434 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.4 11.9 GO:0015671 oxygen transport(GO:0015671)
1.8 9.2 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
2.9 8.7 GO:0097402 neuroblast migration(GO:0097402)
0.1 8.4 GO:0006334 nucleosome assembly(GO:0006334)
0.8 8.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 8.1 GO:0038092 nodal signaling pathway(GO:0038092)
1.1 7.7 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.4 7.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.2 7.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.3 6.7 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.4 6.3 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 6.2 GO:0006342 chromatin silencing(GO:0006342)
0.2 6.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 5.9 GO:0006457 protein folding(GO:0006457)
0.4 5.5 GO:0021854 hypothalamus development(GO:0021854)
0.5 5.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4 5.3 GO:0000076 DNA replication checkpoint(GO:0000076)
0.4 5.2 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
1.0 5.1 GO:0060591 chondroblast differentiation(GO:0060591)
1.6 4.9 GO:1990523 bone regeneration(GO:1990523)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 215 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 16.5 GO:0000786 nucleosome(GO:0000786)
0.0 11.2 GO:0005667 transcription factor complex(GO:0005667)
1.2 9.2 GO:0005833 hemoglobin complex(GO:0005833)
1.0 9.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 9.2 GO:0005730 nucleolus(GO:0005730)
0.1 8.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 8.0 GO:0048786 presynaptic active zone(GO:0048786)
0.1 7.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.6 7.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 6.0 GO:0005871 kinesin complex(GO:0005871)
0.0 5.1 GO:0016607 nuclear speck(GO:0016607)
0.2 4.9 GO:0031527 filopodium membrane(GO:0031527)
0.2 4.9 GO:0001741 XY body(GO:0001741)
0.4 4.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 4.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.4 3.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.7 3.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 3.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 3.7 GO:0000776 kinetochore(GO:0000776)
0.2 3.6 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 288 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.4 11.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 10.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 9.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.8 9.2 GO:0008517 folic acid transporter activity(GO:0008517)
0.4 8.6 GO:0001222 transcription corepressor binding(GO:0001222)
1.1 7.7 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 7.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.6 7.1 GO:0008430 selenium binding(GO:0008430)
0.1 6.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 6.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
1.3 6.7 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.3 6.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 6.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 6.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 6.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 6.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 6.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 5.9 GO:0031072 heat shock protein binding(GO:0031072)
0.1 5.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.3 5.6 GO:0070410 co-SMAD binding(GO:0070410)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.4 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 9.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.3 8.8 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 8.5 PID_PLK1_PATHWAY PLK1 signaling events
0.5 8.3 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 7.5 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.2 7.0 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.2 5.6 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 5.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 5.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.3 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 4.1 PID_AURORA_A_PATHWAY Aurora A signaling
0.3 4.0 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.4 3.6 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 3.4 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 3.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.3 PID_FGF_PATHWAY FGF signaling pathway
0.2 3.2 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.2 PID_MYC_PATHWAY C-MYC pathway
0.1 3.2 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 96 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 14.3 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 10.0 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 8.7 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.4 7.8 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 7.6 REACTOME_KINESINS Genes involved in Kinesins
0.4 6.7 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.4 6.6 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 6.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 6.2 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 6.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 5.1 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 5.1 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.2 4.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 4.5 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 4.5 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 4.5 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 4.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.5 4.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 4.2 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 4.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation