ISMARA results: Zfp652

Motif ID: Zfp652

Z-value: 0.821

Transcription factors associated with Zfp652:

Gene Symbol	Entrez ID	Gene Name
Zfp652	ENSMUSG00000075595.3	Zfp652

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Zfp652	mm10_v2_chr11_+_95712673_95712673	-0.23	1.5e-01	Click!

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Top targets:

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Showing 1 to 20 of 101 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_-_53707532	9.988	ENSMUST00000031093.3	Cckar	cholecystokinin A receptor
chr10_+_26229707	6.770	ENSMUST00000060716.5 ENSMUST00000164660.1	Samd3	sterile alpha motif domain containing 3
chr16_+_30065333	6.567	ENSMUST00000023171.7	Hes1	hairy and enhancer of split 1 (Drosophila)
chr3_+_87971129	4.522	ENSMUST00000160694.1	Nes	nestin
chr3_+_87971071	4.514	ENSMUST00000090973.5	Nes	nestin
chr1_+_153665666	4.479	ENSMUST00000111814.1 ENSMUST00000111810.1	Rgs8	regulator of G-protein signaling 8
chr1_+_153665274	4.195	ENSMUST00000152114.1 ENSMUST00000111812.1	Rgs8	regulator of G-protein signaling 8
chr10_-_92165159	4.035	ENSMUST00000182567.1 ENSMUST00000181604.2 ENSMUST00000181213.1	Rmst	rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr4_-_63403330	3.743	ENSMUST00000035724.4	Akna	AT-hook transcription factor
chr1_-_138847579	3.647	ENSMUST00000093486.3 ENSMUST00000046870.6	Lhx9	LIM homeobox protein 9
chr1_+_153665587	3.512	ENSMUST00000147700.1	Rgs8	regulator of G-protein signaling 8
chr5_+_115908644	3.439	ENSMUST00000141101.1	Cit	citron
chr1_+_153665627	3.435	ENSMUST00000147482.1	Rgs8	regulator of G-protein signaling 8
chr1_+_184034381	3.183	ENSMUST00000048655.7	Dusp10	dual specificity phosphatase 10
chr11_+_98960412	3.149	ENSMUST00000107473.2	Rara	retinoic acid receptor, alpha
chr10_-_6980376	3.055	ENSMUST00000105617.1	Ipcef1	interaction protein for cytohesin exchange factors 1
chrX_-_48034842	2.974	ENSMUST00000039026.7	Apln	apelin
chr7_-_25788635	2.898	ENSMUST00000002677.4 ENSMUST00000085948.4	Axl	AXL receptor tyrosine kinase
chr2_+_167777467	2.389	ENSMUST00000139927.1 ENSMUST00000127441.1	Gm14321	predicted gene 14321
chr9_-_108452377	2.306	ENSMUST00000035232.7	Klhdc8b	kelch domain containing 8B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Showing 1 to 20 of 49 entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	15.6	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
3.3	10.0	GO:0090274	positive regulation of somatostatin secretion(GO:0090274)
2.2	6.6	GO:0021557	oculomotor nerve development(GO:0021557)
0.0	6.4	GO:0043524	negative regulation of neuron apoptotic process(GO:0043524)
0.7	3.6	GO:0035262	gonad morphogenesis(GO:0035262)
0.2	3.6	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.6	3.2	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
1.0	3.1	GO:0060010	Sertoli cell fate commitment(GO:0060010)
1.0	3.0	GO:1904020	regulation of G-protein coupled receptor internalization(GO:1904020)
1.0	2.9	GO:0097350	neutrophil clearance(GO:0097350)
0.2	2.3	GO:0061470	interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.4	2.2	GO:1903527	positive regulation of membrane tubulation(GO:1903527)
0.5	2.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	2.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	2.1	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.2	1.8	GO:0015074	DNA integration(GO:0015074)
0.2	1.8	GO:0061032	visceral serous pericardium development(GO:0061032)
0.4	1.7	GO:0060032	notochord regression(GO:0060032)
0.1	1.6	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.1	1.6	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)

Gene overrepresentation in cellular_component category:

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Showing 1 to 20 of 28 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	11.6	GO:0032809	neuronal cell body membrane(GO:0032809)
0.1	10.0	GO:0043195	terminal bouton(GO:0043195)
0.1	8.0	GO:0005882	intermediate filament(GO:0005882)
0.1	5.0	GO:0002102	podosome(GO:0002102)
0.0	3.7	GO:0001650	fibrillar center(GO:0001650)
0.1	3.4	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	3.4	GO:0016363	nuclear matrix(GO:0016363)
0.1	2.9	GO:0043657	host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.0	2.4	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	1.7	GO:0097542	ciliary tip(GO:0097542)
0.1	1.6	GO:0031105	septin complex(GO:0031105)
0.0	1.6	GO:0016605	PML body(GO:0016605)
0.0	1.6	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.1	1.4	GO:0035102	PRC1 complex(GO:0035102)
0.1	1.1	GO:0005922	connexon complex(GO:0005922)
0.2	1.0	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.2	0.9	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.1	0.9	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.9	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	0.6	GO:0030122	AP-2 adaptor complex(GO:0030122)

Gene overrepresentation in molecular_function category:

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Showing 1 to 20 of 38 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	15.6	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.2	10.0	GO:0008528	G-protein coupled peptide receptor activity(GO:0008528)
0.4	9.7	GO:0008432	JUN kinase binding(GO:0008432)
1.0	9.0	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	3.2	GO:0030165	PDZ domain binding(GO:0030165)
0.3	3.1	GO:0035014	retinoic acid binding(GO:0001972) phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.2	3.0	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.3	2.9	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	2.3	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	2.2	GO:0001786	phosphatidylserine binding(GO:0001786)
1.0	2.1	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.4	2.1	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.2	2.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.2	2.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.5	1.8	GO:0008131	primary amine oxidase activity(GO:0008131)
0.2	1.7	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	1.7	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.5	1.6	GO:0019966	interleukin-1 binding(GO:0019966)
0.3	1.5	GO:0004849	uridine kinase activity(GO:0004849)
0.2	1.5	GO:0008242	omega peptidase activity(GO:0008242)

Gene overrepresentation in C2:CP category:

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Showing 1 to 13 of 13 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	9.5	PID_DELTA_NP63_PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	3.4	PID_RHOA_PATHWAY	RhoA signaling pathway
0.1	3.2	PID_P38_ALPHA_BETA_PATHWAY	Regulation of p38-alpha and p38-beta
0.1	3.1	PID_RXR_VDR_PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	3.1	SA_PTEN_PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	2.2	PID_ARF_3PATHWAY	Arf1 pathway
0.1	1.8	PID_INTEGRIN5_PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	1.7	PID_HEDGEHOG_2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.0	PID_NFAT_TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.9	PID_ATM_PATHWAY	ATM pathway
0.0	0.6	PID_ERBB1_INTERNALIZATION_PATHWAY	Internalization of ErbB1
0.0	0.5	ST_INTERFERON_GAMMA_PATHWAY	Interferon gamma pathway.
0.0	0.5	PID_BETA_CATENIN_DEG_PATHWAY	Degradation of beta catenin

Gene overrepresentation in C2:CP:REACTOME category:

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Showing 1 to 17 of 17 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	15.6	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	Genes involved in G alpha (i) signalling events
0.1	10.0	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.2	5.5	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	3.1	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	2.9	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	Genes involved in Voltage gated Potassium channels
0.2	2.1	REACTOME_P2Y_RECEPTORS	Genes involved in P2Y receptors
0.1	1.8	REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.6	REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	1.5	REACTOME_PYRIMIDINE_METABOLISM	Genes involved in Pyrimidine metabolism
0.1	1.5	REACTOME_GLUTATHIONE_CONJUGATION	Genes involved in Glutathione conjugation
0.1	1.1	REACTOME_GAP_JUNCTION_ASSEMBLY	Genes involved in Gap junction assembly
0.0	1.0	REACTOME_STRIATED_MUSCLE_CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	0.9	REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.6	REACTOME_EGFR_DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.5	REACTOME_REGULATION_OF_IFNG_SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.1	REACTOME_CD28_DEPENDENT_VAV1_PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.1	REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS	Genes involved in Passive Transport by Aquaporins