Motif ID: Zfx_Zfp711

Z-value: 2.419

Transcription factors associated with Zfx_Zfp711:

Gene SymbolEntrez IDGene Name
Zfp711 ENSMUSG00000025529.8 Zfp711
Zfx ENSMUSG00000079509.4 Zfx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp711mm10_v2_chrX_+_112604274_112604274-0.278.6e-02Click!
Zfxmm10_v2_chrX_-_94123087_941231590.153.3e-01Click!


Activity profile for motif Zfx_Zfp711.

activity profile for motif Zfx_Zfp711


Sorted Z-values histogram for motif Zfx_Zfp711

Sorted Z-values for motif Zfx_Zfp711



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfx_Zfp711

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_180225812 5.214 ENSMUST00000015791.5
 Lama5
laminin, alpha 5
chr6_-_38876163 4.441 ENSMUST00000161779.1
 Hipk2
homeodomain interacting protein kinase 2
chr14_-_34502522 4.312 ENSMUST00000171551.1
 Bmpr1a
bone morphogenetic protein receptor, type 1A
chr4_+_137468767 4.019 ENSMUST00000030547.8
ENSMUST00000171332.1
 Hspg2

perlecan (heparan sulfate proteoglycan 2)

chr9_+_72662473 3.691 ENSMUST00000184450.1
ENSMUST00000183375.1
 Nedd4

neural precursor cell expressed, developmentally down-regulated 4

chr5_+_144768536 3.618 ENSMUST00000128550.1
 Trrap
transformation/transcription domain-associated protein
chr11_+_60104971 3.571 ENSMUST00000064190.6
 Rai1
retinoic acid induced 1
chr1_-_63114255 3.397 ENSMUST00000153992.1
ENSMUST00000165066.1
ENSMUST00000172416.1
ENSMUST00000137511.1
 Ino80d



INO80 complex subunit D



chr8_+_127064107 3.248 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
 Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr11_+_60105079 3.236 ENSMUST00000132012.1
 Rai1
retinoic acid induced 1
chr18_+_65581704 3.187 ENSMUST00000182979.1
 Zfp532
zinc finger protein 532
chr7_+_102267795 3.171 ENSMUST00000033289.4
 Stim1
stromal interaction molecule 1
chr2_-_157079212 3.122 ENSMUST00000069098.6
 Soga1
suppressor of glucose, autophagy associated 1
chr12_+_70825492 3.034 ENSMUST00000057859.7
 Frmd6
FERM domain containing 6
chr19_-_30175414 3.012 ENSMUST00000025778.7
 Gldc
glycine decarboxylase
chr18_+_24709436 2.944 ENSMUST00000037097.7
 Fhod3
formin homology 2 domain containing 3
chr4_+_109978004 2.913 ENSMUST00000061187.3
 Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr2_+_154436437 2.803 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
 Cbfa2t2



core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)



chrX_+_99821021 2.783 ENSMUST00000096363.2
 Tmem28
transmembrane protein 28
chr7_-_105787544 2.764 ENSMUST00000078482.5
ENSMUST00000154659.1
 Dchs1

dachsous 1 (Drosophila)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,169 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 11.4 GO:0035329 hippo signaling(GO:0035329)
0.3 9.8 GO:0007520 myoblast fusion(GO:0007520)
1.4 8.2 GO:0003383 apical constriction(GO:0003383)
0.9 8.0 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.4 7.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.4 7.5 GO:0006999 nuclear pore organization(GO:0006999)
2.5 7.4 GO:0021998 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
1.5 6.2 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.8 6.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 5.9 GO:0035411 catenin import into nucleus(GO:0035411)
0.2 5.6 GO:0001738 morphogenesis of a polarized epithelium(GO:0001738)
0.5 5.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 5.5 GO:0043171 peptide catabolic process(GO:0043171)
0.4 5.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 5.3 GO:0036503 ERAD pathway(GO:0036503)
0.9 5.2 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
1.0 5.0 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.5 5.0 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
1.2 4.8 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
1.2 4.7 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 372 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 54.1 GO:0005654 nucleoplasm(GO:0005654)
0.2 26.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 13.5 GO:0005901 caveola(GO:0005901)
0.0 13.5 GO:0005783 endoplasmic reticulum(GO:0005783)
0.2 10.4 GO:0005811 lipid particle(GO:0005811)
0.0 10.4 GO:0005667 transcription factor complex(GO:0005667)
0.1 9.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 8.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 7.3 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.6 7.0 GO:0000812 Swr1 complex(GO:0000812)
1.7 6.8 GO:0043259 laminin-10 complex(GO:0043259)
0.1 6.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.2 6.7 GO:0016592 mediator complex(GO:0016592)
0.5 6.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 6.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 6.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 6.2 GO:0005643 nuclear pore(GO:0005643)
0.1 6.2 GO:0001650 fibrillar center(GO:0001650)
0.7 6.1 GO:1990909 Wnt signalosome(GO:1990909)
0.1 6.1 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 634 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 21.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.3 11.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.5 11.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 11.5 GO:0008013 beta-catenin binding(GO:0008013)
0.2 11.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 11.3 GO:0035326 enhancer binding(GO:0035326)
0.5 9.6 GO:0070411 I-SMAD binding(GO:0070411)
0.1 9.2 GO:0004386 helicase activity(GO:0004386)
0.3 8.5 GO:0046965 retinoid X receptor binding(GO:0046965)
1.1 8.4 GO:0046790 virion binding(GO:0046790)
0.4 8.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.2 8.1 GO:0098821 BMP receptor activity(GO:0098821)
0.2 7.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.4 7.4 GO:0035497 cAMP response element binding(GO:0035497)
0.4 7.2 GO:0070410 co-SMAD binding(GO:0070410)
0.2 7.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.2 6.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 6.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 6.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 6.4 GO:0003713 transcription coactivator activity(GO:0003713)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 105 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 24.5 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.4 18.8 PID_BMP_PATHWAY BMP receptor signaling
0.5 14.5 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.2 12.6 PID_P53_REGULATION_PATHWAY p53 pathway
0.2 11.4 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 10.2 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
1.2 9.9 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 9.6 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.1 7.8 PID_E2F_PATHWAY E2F transcription factor network
0.3 7.5 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.2 6.7 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.2 6.5 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.2 6.3 PID_MYC_PATHWAY C-MYC pathway
0.2 6.2 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.2 5.5 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 5.4 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 4.9 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 4.6 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 4.4 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.1 4.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 180 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 14.7 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.4 14.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.3 10.8 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.4 10.7 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.3 8.9 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3 8.8 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.3 8.4 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.5 8.2 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 8.1 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 8.1 REACTOME_UNFOLDED_PROTEIN_RESPONSE Genes involved in Unfolded Protein Response
0.3 7.3 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.3 6.8 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 6.6 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.2 6.2 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 5.2 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.1 5.1 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 4.8 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.7 4.7 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 4.7 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.3 4.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane