Motif ID: Ascl2

Z-value: 0.832


Transcription factors associated with Ascl2:

Gene SymbolEntrez IDGene Name
Ascl2 ENSMUSG00000009248.5 Ascl2



Activity profile for motif Ascl2.

activity profile for motif Ascl2


Sorted Z-values histogram for motif Ascl2

Sorted Z-values for motif Ascl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ascl2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_120340569 2.604 ENSMUST00000037286.8
 C1ql2
complement component 1, q subcomponent-like 2
chr8_+_105518736 2.473 ENSMUST00000034363.5
 Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
chr12_-_40037387 2.279 ENSMUST00000146905.1
 Arl4a
ADP-ribosylation factor-like 4A
chr5_-_106458440 2.217 ENSMUST00000086795.6
 Barhl2
BarH-like 2 (Drosophila)
chr2_-_148046896 2.135 ENSMUST00000172928.1
ENSMUST00000047315.3
 Foxa2

forkhead box A2

chr12_-_40038025 2.058 ENSMUST00000101472.3
 Arl4a
ADP-ribosylation factor-like 4A
chr16_+_91269759 2.058 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr8_-_105471481 2.000 ENSMUST00000014990.6
 Tppp3
tubulin polymerization-promoting protein family member 3
chr7_+_142471838 1.776 ENSMUST00000038946.2
 Lsp1
lymphocyte specific 1
chr6_-_12749193 1.740 ENSMUST00000046121.6
ENSMUST00000172356.1
 Thsd7a

thrombospondin, type I, domain containing 7A

chr8_+_31091593 1.712 ENSMUST00000161713.1
 Dusp26
dual specificity phosphatase 26 (putative)
chr7_+_142472080 1.592 ENSMUST00000105966.1
 Lsp1
lymphocyte specific 1
chr7_-_28302238 1.554 ENSMUST00000108315.3
 Dll3
delta-like 3 (Drosophila)
chrX_-_106485214 1.526 ENSMUST00000039447.7
 Fndc3c1
fibronectin type III domain containing 3C1
chr9_+_74848437 1.505 ENSMUST00000161862.1
ENSMUST00000162089.1
ENSMUST00000160017.1
ENSMUST00000160950.1
 Gm16551


Gm20649
predicted gene 16551


predicted gene 20649
chr2_-_170406501 1.502 ENSMUST00000154650.1
 Bcas1
breast carcinoma amplified sequence 1
chr17_-_27513341 1.469 ENSMUST00000118161.1
 Grm4
glutamate receptor, metabotropic 4
chr6_+_4755327 1.448 ENSMUST00000176551.1
 Peg10
paternally expressed 10
chr2_-_122611238 1.434 ENSMUST00000028624.8
 Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr12_+_116485714 1.399 ENSMUST00000070733.7
 Ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 161 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.2 2.5 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977)
0.1 2.2 GO:0001709 cell fate determination(GO:0001709)
0.7 2.1 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.0 2.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 1.9 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.6 1.7 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 1.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.3 1.6 GO:0007386 compartment pattern specification(GO:0007386)
0.0 1.6 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.0 1.6 GO:0001890 placenta development(GO:0001890)
0.1 1.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.5 1.4 GO:0006601 creatine biosynthetic process(GO:0006601)
0.5 1.4 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 1.4 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 1.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.3 GO:0021670 lateral ventricle development(GO:0021670)
0.0 1.3 GO:0006334 nucleosome assembly(GO:0006334)
0.1 1.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 1.2 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.7 GO:0005667 transcription factor complex(GO:0005667)
0.3 2.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 2.9 GO:0005581 collagen trimer(GO:0005581)
0.1 2.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 1.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 1.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.0 GO:0070852 cell body fiber(GO:0070852)
0.1 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 0.8 GO:0005940 septin ring(GO:0005940)
0.3 0.8 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.8 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.7 GO:0030478 actin cap(GO:0030478)
0.1 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.7 GO:0005605 basal lamina(GO:0005605)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 117 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.0 GO:0003924 GTPase activity(GO:0003924)
0.0 4.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 4.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 3.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 2.9 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.6 1.7 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.3 1.7 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.0 1.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.3 1.5 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.1 1.4 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 1.4 GO:0005112 Notch binding(GO:0005112)
0.0 1.4 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.1 1.3 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 1.1 GO:0042287 MHC protein binding(GO:0042287)
0.1 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)