Motif ID: Atf1_Creb5

Z-value: 0.379

Transcription factors associated with Atf1_Creb5:

Gene SymbolEntrez IDGene Name
Atf1 ENSMUSG00000023027.6 Atf1
Creb5 ENSMUSG00000053007.6 Creb5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf1mm10_v2_chr15_+_100227819_100227856-0.301.4e-01Click!
Creb5mm10_v2_chr6_+_53573364_53573394-0.057.9e-01Click!


Activity profile for motif Atf1_Creb5.

activity profile for motif Atf1_Creb5


Sorted Z-values histogram for motif Atf1_Creb5

Sorted Z-values for motif Atf1_Creb5



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf1_Creb5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_155276297 1.757 ENSMUST00000029128.3
 Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr9_-_98032983 1.630 ENSMUST00000162295.1
 Clstn2
calsyntenin 2
chr9_+_53850243 1.190 ENSMUST00000048485.5
 Sln
sarcolipin
chr5_-_124032214 1.146 ENSMUST00000040967.7
 Vps37b
vacuolar protein sorting 37B (yeast)
chr6_-_55681257 1.099 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr6_+_54681687 1.086 ENSMUST00000046276.6
 2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr10_-_17947997 0.971 ENSMUST00000037879.6
 Heca
headcase homolog (Drosophila)
chr15_-_84105662 0.864 ENSMUST00000082365.5
 Sult4a1
sulfotransferase family 4A, member 1
chr10_-_102490418 0.834 ENSMUST00000020040.3
 Nts
neurotensin
chr10_+_29211637 0.815 ENSMUST00000092627.4
 9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr9_-_96752822 0.798 ENSMUST00000152594.1
 Zbtb38
zinc finger and BTB domain containing 38
chr17_-_24689901 0.768 ENSMUST00000007236.4
 Syngr3
synaptogyrin 3
chr9_+_40269273 0.767 ENSMUST00000176185.1
 Scn3b
sodium channel, voltage-gated, type III, beta
chr12_+_102554966 0.754 ENSMUST00000021610.5
 Chga
chromogranin A
chr9_+_40269202 0.740 ENSMUST00000114956.3
ENSMUST00000049941.5
 Scn3b

sodium channel, voltage-gated, type III, beta

chr8_+_25849618 0.693 ENSMUST00000098858.3
 Kcnu1
potassium channel, subfamily U, member 1
chr17_-_26508463 0.654 ENSMUST00000025025.6
 Dusp1
dual specificity phosphatase 1
chr16_-_23988852 0.649 ENSMUST00000023151.5
 Bcl6
B cell leukemia/lymphoma 6
chr11_+_83302817 0.640 ENSMUST00000142680.1
 Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr5_-_109558957 0.607 ENSMUST00000044579.7
 Crlf2
cytokine receptor-like factor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 111 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 1.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 1.5 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.3 1.2 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.4 1.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 1.1 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 1.1 GO:0035904 aorta development(GO:0035904)
0.0 0.9 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.9 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.3 0.8 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.0 0.8 GO:0008542 visual learning(GO:0008542)
0.2 0.7 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 0.7 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 0.7 GO:0008209 androgen metabolic process(GO:0008209)
0.0 0.7 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.2 0.6 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.6 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 0.6 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.1 0.6 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.6 GO:0030432 peristalsis(GO:0030432)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 1.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 0.9 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2 0.8 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.8 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.6 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0005776 autophagosome(GO:0005776)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.3 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 79 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 1.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.1 GO:0030276 clathrin binding(GO:0030276)
0.0 1.0 GO:0031489 myosin V binding(GO:0031489)
0.1 0.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.2 0.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 0.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.6 GO:0030553 cGMP binding(GO:0030553)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0004896 cytokine receptor activity(GO:0004896)