Motif ID: Atf4
Z-value: 1.120
Transcription factors associated with Atf4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Atf4 | ENSMUSG00000042406.7 | Atf4 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Atf4 | mm10_v2_chr15_+_80255184_80255263 | 0.51 | 7.4e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.6 | 6.4 | GO:0070858 | negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252) |
1.5 | 8.8 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
1.0 | 3.0 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) |
0.9 | 2.6 | GO:0048818 | embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364) |
0.8 | 2.5 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
0.7 | 2.2 | GO:1904706 | response to cisplatin(GO:0072718) negative regulation of vascular smooth muscle cell proliferation(GO:1904706) |
0.5 | 2.1 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
0.4 | 1.3 | GO:0006592 | ornithine biosynthetic process(GO:0006592) |
0.4 | 1.3 | GO:0006106 | fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401) |
0.4 | 1.3 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
0.3 | 0.9 | GO:0051031 | tRNA transport(GO:0051031) |
0.2 | 1.2 | GO:1903352 | ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352) |
0.2 | 0.6 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
0.2 | 0.9 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.2 | 0.5 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
0.2 | 0.5 | GO:0015960 | diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) |
0.2 | 0.8 | GO:0006561 | proline biosynthetic process(GO:0006561) |
0.2 | 0.5 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
0.1 | 0.7 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
0.1 | 1.2 | GO:0009396 | folic acid-containing compound biosynthetic process(GO:0009396) |
0.1 | 3.2 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
0.1 | 0.4 | GO:0051708 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
0.1 | 0.6 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
0.1 | 0.3 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
0.1 | 0.4 | GO:0010886 | positive regulation of cholesterol storage(GO:0010886) regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368) |
0.1 | 2.9 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
0.1 | 1.8 | GO:0031065 | positive regulation of histone deacetylation(GO:0031065) |
0.1 | 0.7 | GO:2000194 | regulation of female gonad development(GO:2000194) |
0.1 | 0.2 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
0.1 | 0.6 | GO:0018065 | protein-cofactor linkage(GO:0018065) |
0.1 | 1.9 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
0.1 | 1.6 | GO:0010955 | negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318) |
0.0 | 0.7 | GO:0009048 | dosage compensation by inactivation of X chromosome(GO:0009048) |
0.0 | 2.5 | GO:0010718 | positive regulation of epithelial to mesenchymal transition(GO:0010718) |
0.0 | 0.4 | GO:0060613 | fat pad development(GO:0060613) |
0.0 | 0.3 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
0.0 | 0.3 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
0.0 | 1.4 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
0.0 | 0.8 | GO:0006491 | N-glycan processing(GO:0006491) |
0.0 | 0.2 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
0.0 | 1.7 | GO:0006096 | glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757) |
0.0 | 0.9 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
0.0 | 0.2 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
0.0 | 0.3 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.0 | 0.1 | GO:0006983 | ER overload response(GO:0006983) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 3.0 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.2 | 0.6 | GO:1990037 | Lewy body core(GO:1990037) |
0.2 | 1.4 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.1 | 0.5 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
0.1 | 0.4 | GO:0042825 | TAP complex(GO:0042825) |
0.1 | 0.9 | GO:0031528 | microvillus membrane(GO:0031528) |
0.1 | 0.2 | GO:0005745 | m-AAA complex(GO:0005745) |
0.1 | 0.4 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.0 | 0.3 | GO:0031931 | TORC1 complex(GO:0031931) |
0.0 | 0.3 | GO:0043203 | axon hillock(GO:0043203) |
0.0 | 1.7 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
0.0 | 1.1 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 2.2 | GO:0005901 | caveola(GO:0005901) |
0.0 | 0.1 | GO:0070552 | BRISC complex(GO:0070552) |
0.0 | 0.1 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.0 | 0.2 | GO:0005869 | dynactin complex(GO:0005869) |
0.0 | 0.0 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
0.0 | 0.9 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 0.6 | GO:0000793 | condensed chromosome(GO:0000793) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.5 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
0.8 | 3.1 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
0.5 | 2.2 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
0.5 | 3.0 | GO:0045340 | mercury ion binding(GO:0045340) |
0.4 | 1.3 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
0.4 | 1.2 | GO:0004477 | methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) |
0.3 | 6.4 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.2 | 1.3 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
0.2 | 0.8 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
0.2 | 0.6 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
0.2 | 1.2 | GO:0015189 | L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189) |
0.2 | 0.8 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.2 | 0.5 | GO:0004816 | asparagine-tRNA ligase activity(GO:0004816) |
0.2 | 0.5 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
0.1 | 0.6 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
0.1 | 0.4 | GO:0023029 | peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980) |
0.1 | 0.2 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
0.1 | 0.3 | GO:0019966 | interleukin-1 binding(GO:0019966) |
0.1 | 5.2 | GO:0000049 | tRNA binding(GO:0000049) |
0.1 | 16.1 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.1 | 4.8 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.1 | 1.6 | GO:0005112 | Notch binding(GO:0005112) |
0.1 | 0.3 | GO:0000339 | RNA cap binding(GO:0000339) translation activator activity(GO:0008494) |
0.0 | 0.9 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.0 | 0.1 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
0.0 | 1.0 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) |
0.0 | 0.2 | GO:0050815 | phosphoserine binding(GO:0050815) |
0.0 | 0.5 | GO:0070628 | proteasome binding(GO:0070628) |
0.0 | 0.2 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.0 | 0.3 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.0 | 0.8 | GO:0004896 | cytokine receptor activity(GO:0004896) |
0.0 | 0.3 | GO:0008483 | transaminase activity(GO:0008483) |