Motif ID: Atf5

Z-value: 0.965


Transcription factors associated with Atf5:

Gene SymbolEntrez IDGene Name
Atf5 ENSMUSG00000038539.8 Atf5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf5mm10_v2_chr7_-_44816586_448166580.413.8e-02Click!


Activity profile for motif Atf5.

activity profile for motif Atf5


Sorted Z-values histogram for motif Atf5

Sorted Z-values for motif Atf5



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 119 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_56535047 3.910 ENSMUST00000178477.2
 Nkx2-1
NK2 homeobox 1
chr7_+_51621830 1.964 ENSMUST00000032710.5
 Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chrX_+_41401304 1.792 ENSMUST00000076349.5
 Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr4_-_82705735 1.777 ENSMUST00000155821.1
 Nfib
nuclear factor I/B
chr2_+_124610573 1.647 ENSMUST00000103239.3
ENSMUST00000103240.2
 Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chrX_+_41401128 1.469 ENSMUST00000115103.2
 Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr15_-_102529025 1.338 ENSMUST00000096143.1
 Atf7
activating transcription factor 7
chrX_+_166344692 1.251 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
 Gpm6b





glycoprotein m6b





chr12_+_89812467 1.136 ENSMUST00000110133.2
ENSMUST00000110130.2
 Nrxn3

neurexin III

chr16_-_46010212 1.034 ENSMUST00000130481.1
 Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chrX_+_41401476 0.998 ENSMUST00000165288.1
 Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr16_-_16560201 0.976 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
 Fgd4


FYVE, RhoGEF and PH domain containing 4


chr4_-_11322109 0.922 ENSMUST00000084892.5
ENSMUST00000128024.1
 Dpy19l4

dpy-19-like 4 (C. elegans)

chr4_-_91376433 0.917 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
 Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chr18_-_23041641 0.900 ENSMUST00000097651.3
 Nol4
nucleolar protein 4
chr10_-_87493651 0.886 ENSMUST00000020243.7
 Ascl1
achaete-scute complex homolog 1 (Drosophila)
chr4_+_86748526 0.867 ENSMUST00000082026.7
ENSMUST00000045512.8
 Dennd4c

DENN/MADD domain containing 4C

chr15_-_79164477 0.857 ENSMUST00000040019.4
 Sox10
SRY-box containing gene 10
chrX_-_41911877 0.850 ENSMUST00000047037.8
 Thoc2
THO complex 2
chr18_+_64254359 0.837 ENSMUST00000025477.7
 St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.3 GO:0001919 regulation of receptor recycling(GO:0001919)
1.3 3.9 GO:0021759 globus pallidus development(GO:0021759)
0.1 2.0 GO:0001504 neurotransmitter uptake(GO:0001504)
0.4 1.8 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 1.6 GO:0030035 microspike assembly(GO:0030035)
0.1 1.6 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 1.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 1.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 1.3 GO:0035904 aorta development(GO:0035904)
0.1 1.1 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 1.0 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.3 0.9 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.3 0.9 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) musculoskeletal movement, spinal reflex action(GO:0050883) olfactory pit development(GO:0060166)
0.1 0.9 GO:0048484 enteric nervous system development(GO:0048484)
0.3 0.8 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.2 0.8 GO:1990743 protein sialylation(GO:1990743)
0.1 0.7 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.7 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.6 GO:0005667 transcription factor complex(GO:0005667)
0.4 4.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 2.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.9 GO:0030175 filopodium(GO:0030175)
0.1 1.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.8 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 1.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.1 0.9 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.8 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.7 GO:0044308 axonal spine(GO:0044308)
0.1 0.7 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 0.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.6 GO:0030478 actin cap(GO:0030478)
0.1 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 4.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.3 3.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 2.1 GO:0051015 actin filament binding(GO:0051015)
0.1 2.0 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 1.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 1.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.9 GO:0035496 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 0.7 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.1 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 0.6 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)