Motif ID: Atf6

Z-value: 1.236


Transcription factors associated with Atf6:

Gene SymbolEntrez IDGene Name
Atf6 ENSMUSG00000026663.6 Atf6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf6mm10_v2_chr1_-_170867761_170867784-0.067.6e-01Click!


Activity profile for motif Atf6.

activity profile for motif Atf6


Sorted Z-values histogram for motif Atf6

Sorted Z-values for motif Atf6



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf6

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_23988852 7.693 ENSMUST00000023151.5
 Bcl6
B cell leukemia/lymphoma 6
chr12_+_82616885 4.973 ENSMUST00000161801.1
 Rgs6
regulator of G-protein signaling 6
chr5_+_134986191 4.905 ENSMUST00000094245.2
 Cldn3
claudin 3
chr3_+_123267445 4.659 ENSMUST00000047923.7
 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr8_-_70700070 3.977 ENSMUST00000116172.1
 Gm11175
predicted gene 11175
chr6_-_126740151 3.800 ENSMUST00000112242.1
 Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr6_-_136173492 3.780 ENSMUST00000111905.1
 Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr5_-_136170634 3.702 ENSMUST00000041048.1
 Orai2
ORAI calcium release-activated calcium modulator 2
chr1_-_52091066 3.558 ENSMUST00000105087.1
 Gm3940
predicted gene 3940
chr6_-_101377897 3.424 ENSMUST00000075994.6
 Pdzrn3
PDZ domain containing RING finger 3
chr6_+_77242644 3.339 ENSMUST00000159616.1
 Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr6_+_77242715 3.323 ENSMUST00000161677.1
 Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr7_+_126950518 3.257 ENSMUST00000106335.1
ENSMUST00000146017.1
 Sez6l2

seizure related 6 homolog like 2

chr5_+_35056813 3.220 ENSMUST00000101298.2
ENSMUST00000114270.1
ENSMUST00000133381.1
 Dok7


docking protein 7


chr18_-_31447383 3.190 ENSMUST00000025110.3
 Syt4
synaptotagmin IV
chr8_-_70487314 3.006 ENSMUST00000045286.7
 Tmem59l
transmembrane protein 59-like
chr2_+_155276297 2.987 ENSMUST00000029128.3
 Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr7_+_126950687 2.887 ENSMUST00000106333.1
 Sez6l2
seizure related 6 homolog like 2
chr10_+_29211637 2.831 ENSMUST00000092627.4
 9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr11_+_69991061 2.737 ENSMUST00000018711.8
 Gabarap
gamma-aminobutyric acid receptor associated protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 163 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 10.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.3 8.5 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.3 8.0 GO:0002091 negative regulation of receptor internalization(GO:0002091)
2.6 7.7 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.5 5.7 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.3 5.2 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 5.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.6 5.1 GO:0090166 Golgi disassembly(GO:0090166)
0.6 4.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4 4.8 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 4.5 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.2 4.0 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.3 3.9 GO:0045176 apical protein localization(GO:0045176)
0.0 3.9 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.2 3.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.4 3.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 3.1 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094)
0.2 2.9 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.9 2.6 GO:0002159 desmosome assembly(GO:0002159)
0.4 2.6 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 73 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 14.3 GO:0043025 neuronal cell body(GO:0043025)
0.1 12.9 GO:0030426 growth cone(GO:0030426)
0.1 12.6 GO:0031594 neuromuscular junction(GO:0031594)
0.2 10.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 7.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.6 6.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 6.2 GO:0005657 replication fork(GO:0005657)
0.3 5.7 GO:0000421 autophagosome membrane(GO:0000421)
0.1 5.4 GO:0031201 SNARE complex(GO:0031201)
0.1 5.3 GO:0030667 secretory granule membrane(GO:0030667)
0.3 5.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 4.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 4.8 GO:0097060 synaptic membrane(GO:0097060)
0.0 4.4 GO:0031252 cell leading edge(GO:0031252)
0.2 3.2 GO:0031045 dense core granule(GO:0031045)
0.4 3.1 GO:0005827 polar microtubule(GO:0005827)
0.0 3.0 GO:0043209 myelin sheath(GO:0043209)
0.5 2.4 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 2.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 2.4 GO:0031430 M band(GO:0031430)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 113 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 7.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 6.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 5.5 GO:0005096 GTPase activator activity(GO:0005096)
0.1 5.3 GO:0005158 insulin receptor binding(GO:0005158)
0.5 4.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.3 4.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 4.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.3 4.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.4 3.8 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 3.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 3.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 3.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 3.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.8 3.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.4 3.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 2.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 2.7 GO:0050811 GABA receptor binding(GO:0050811)
0.4 2.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.3 2.6 GO:0035184 histone threonine kinase activity(GO:0035184)