Motif ID: Atf7_E4f1

Z-value: 1.265

Transcription factors associated with Atf7_E4f1:

Gene SymbolEntrez IDGene Name
Atf7 ENSMUSG00000052414.9 Atf7
Atf7 ENSMUSG00000071584.1 Atf7
E4f1 ENSMUSG00000024137.8 E4f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E4f1mm10_v2_chr17_-_24455265_24455345-0.707.2e-05Click!
Atf7mm10_v2_chr15_-_102529025_102529025-0.708.1e-05Click!


Activity profile for motif Atf7_E4f1.

activity profile for motif Atf7_E4f1


Sorted Z-values histogram for motif Atf7_E4f1

Sorted Z-values for motif Atf7_E4f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf7_E4f1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_106458440 6.708 ENSMUST00000086795.6
 Barhl2
BarH-like 2 (Drosophila)
chr6_-_23248264 6.659 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr3_+_67374116 5.990 ENSMUST00000061322.8
 Mlf1
myeloid leukemia factor 1
chr4_+_141301228 5.990 ENSMUST00000006614.2
 Epha2
Eph receptor A2
chr3_+_67374091 5.443 ENSMUST00000077916.5
 Mlf1
myeloid leukemia factor 1
chr7_-_144939823 5.326 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr9_-_20976762 4.996 ENSMUST00000054197.5
 S1pr2
sphingosine-1-phosphate receptor 2
chr8_+_116921735 4.828 ENSMUST00000034205.4
 Cenpn
centromere protein N
chr4_+_111720187 4.784 ENSMUST00000084354.3
 Spata6
spermatogenesis associated 6
chr3_+_135212557 4.712 ENSMUST00000062893.7
 Cenpe
centromere protein E
chr7_-_137314394 4.555 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr3_-_36571952 4.463 ENSMUST00000029270.3
 Ccna2
cyclin A2
chr17_-_71526819 4.444 ENSMUST00000024851.9
 Ndc80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr3_+_127553462 4.440 ENSMUST00000043108.4
 4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr19_+_59260878 4.248 ENSMUST00000026084.3
 Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr3_+_40800054 4.071 ENSMUST00000168287.1
 Plk4
polo-like kinase 4
chr11_-_84525514 3.863 ENSMUST00000018842.7
 Lhx1
LIM homeobox protein 1
chr8_+_92674289 3.663 ENSMUST00000034185.6
 Irx6
Iroquois related homeobox 6 (Drosophila)
chr8_-_92355764 3.633 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
 4933436C20Rik



RIKEN cDNA 4933436C20 gene



chr13_+_8885937 3.496 ENSMUST00000177397.1
ENSMUST00000177400.1
ENSMUST00000177447.1
 Idi1


isopentenyl-diphosphate delta isomerase



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 202 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 12.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
1.8 9.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.3 7.3 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.2 7.1 GO:0034508 centromere complex assembly(GO:0034508)
1.2 7.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
1.7 6.7 GO:0002074 extraocular skeletal muscle development(GO:0002074) pulmonary myocardium development(GO:0003350) subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
1.3 6.7 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918)
1.1 6.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 6.7 GO:0001709 cell fate determination(GO:0001709)
0.0 6.3 GO:0042254 ribosome biogenesis(GO:0042254)
2.0 6.0 GO:0014028 notochord formation(GO:0014028)
1.2 5.8 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 5.6 GO:0048864 stem cell development(GO:0048864)
0.8 5.3 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
1.7 5.0 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.5 4.9 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.4 4.8 GO:0044458 motile cilium assembly(GO:0044458)
0.7 4.7 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.4 4.5 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.2 4.4 GO:0009409 response to cold(GO:0009409)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 102 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 19.8 GO:0005667 transcription factor complex(GO:0005667)
0.1 17.6 GO:0031514 motile cilium(GO:0031514)
0.1 12.2 GO:0000776 kinetochore(GO:0000776)
0.1 10.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.7 8.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 6.6 GO:0005730 nucleolus(GO:0005730)
0.7 5.8 GO:0098536 deuterosome(GO:0098536)
0.0 5.8 GO:0031965 nuclear membrane(GO:0031965)
0.1 5.6 GO:0015934 large ribosomal subunit(GO:0015934)
0.1 5.4 GO:0005844 polysome(GO:0005844)
0.1 5.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 4.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 4.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.6 4.5 GO:0001940 male pronucleus(GO:0001940)
1.1 4.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.5 4.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 4.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
1.3 3.8 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.2 3.7 GO:0031045 dense core granule(GO:0031045)
0.0 3.7 GO:0031256 leading edge membrane(GO:0031256)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 146 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 15.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 14.7 GO:0003677 DNA binding(GO:0003677)
0.1 13.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.5 6.9 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.6 6.7 GO:0003680 AT DNA binding(GO:0003680)
0.1 6.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 5.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 5.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 5.3 GO:0070064 proline-rich region binding(GO:0070064)
0.4 5.0 GO:0051010 microtubule plus-end binding(GO:0051010)
1.0 4.8 GO:0032027 myosin light chain binding(GO:0032027)
1.2 4.7 GO:0043515 kinetochore binding(GO:0043515)
0.3 4.7 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 4.6 GO:0005003 ephrin receptor activity(GO:0005003)
1.4 4.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 3.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.5 3.8 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 3.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 3.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 2.7 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)