Motif ID: Atoh1_Bhlhe23

Z-value: 0.609

Transcription factors associated with Atoh1_Bhlhe23:

Gene SymbolEntrez IDGene Name
Atoh1 ENSMUSG00000073043.4 Atoh1
Bhlhe23 ENSMUSG00000045493.3 Bhlhe23

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bhlhe23mm10_v2_chr2_-_180776749_180776749-0.321.1e-01Click!


Activity profile for motif Atoh1_Bhlhe23.

activity profile for motif Atoh1_Bhlhe23


Sorted Z-values histogram for motif Atoh1_Bhlhe23

Sorted Z-values for motif Atoh1_Bhlhe23



Network of associatons between targets according to the STRING database.



First level regulatory network of Atoh1_Bhlhe23

PNG image of the network

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Top targets:


Showing 1 to 20 of 99 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_177444653 5.602 ENSMUST00000094276.3
 Zbtb18
zinc finger and BTB domain containing 18
chr9_-_21918089 2.838 ENSMUST00000128442.1
ENSMUST00000119055.1
ENSMUST00000122211.1
ENSMUST00000115351.3
 Rab3d



RAB3D, member RAS oncogene family



chr3_-_120886691 2.265 ENSMUST00000182099.1
ENSMUST00000183168.1
ENSMUST00000183276.1
ENSMUST00000182124.1
 6530403H02Rik



RIKEN cDNA 6530403H02 gene



chr11_-_98329641 2.247 ENSMUST00000041685.6
 Neurod2
neurogenic differentiation 2
chr11_+_58954675 2.107 ENSMUST00000047697.5
ENSMUST00000108817.3
 Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr2_-_29253001 2.105 ENSMUST00000071201.4
 Ntng2
netrin G2
chr2_-_79456750 2.065 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr11_-_75796048 1.880 ENSMUST00000021209.7
 Doc2b
double C2, beta
chrX_-_53608979 1.864 ENSMUST00000123034.1
 Gm14597
predicted gene 14597
chr9_+_72985504 1.774 ENSMUST00000156879.1
 Ccpg1
cell cycle progression 1
chr3_-_84259812 1.515 ENSMUST00000107691.1
 Trim2
tripartite motif-containing 2
chr1_+_177445660 1.504 ENSMUST00000077225.6
 Zbtb18
zinc finger and BTB domain containing 18
chr9_+_72985568 1.374 ENSMUST00000150826.2
ENSMUST00000085350.4
ENSMUST00000140675.1
 Ccpg1


cell cycle progression 1


chr17_-_47016956 1.327 ENSMUST00000165525.1
 Gm16494
predicted gene 16494
chr5_-_144223516 1.190 ENSMUST00000085701.6
 Tecpr1
tectonin beta-propeller repeat containing 1
chr3_+_138065052 1.184 ENSMUST00000163080.2
 1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr5_-_124187150 1.170 ENSMUST00000161938.1
 Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr17_+_82539258 1.169 ENSMUST00000097278.3
 Gm6594
predicted pseudogene 6594
chr1_+_15287259 1.145 ENSMUST00000175681.1
 Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr16_+_43235856 1.136 ENSMUST00000146708.1
 Zbtb20
zinc finger and BTB domain containing 20

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.1 GO:0021766 hippocampus development(GO:0021766)
0.8 3.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 3.0 GO:0021860 pyramidal neuron development(GO:0021860)
0.6 2.8 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.7 2.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.5 2.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.2 2.1 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 1.9 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 1.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.4 1.3 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 1.2 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.2 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.3 1.1 GO:1903288 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.2 1.1 GO:0032796 uropod organization(GO:0032796)
0.2 1.1 GO:0071318 cellular response to ATP(GO:0071318)
0.1 1.0 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.3 0.8 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.8 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.8 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.8 GO:0060997 dendritic spine morphogenesis(GO:0060997)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.1 GO:0045171 intercellular bridge(GO:0045171)
0.6 3.0 GO:0097441 basilar dendrite(GO:0097441)
0.2 2.8 GO:0042588 zymogen granule(GO:0042588)
0.1 2.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.9 GO:0031201 SNARE complex(GO:0031201)
0.1 1.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.2 GO:0000421 autophagosome membrane(GO:0000421)
0.2 1.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.1 GO:0070938 contractile ring(GO:0070938)
0.0 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.8 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.8 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.6 GO:0070888 E-box binding(GO:0070888)
0.1 3.0 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 2.8 GO:0031489 myosin V binding(GO:0031489)
0.0 2.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.5 GO:0017022 myosin binding(GO:0017022)
0.0 1.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.1 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 1.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0034237 AMP binding(GO:0016208) protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.6 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) purinergic receptor activity(GO:0035586)