Motif ID: Barhl2

Z-value: 0.530


Transcription factors associated with Barhl2:

Gene SymbolEntrez IDGene Name
Barhl2 ENSMUSG00000034384.10 Barhl2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Barhl2mm10_v2_chr5_-_106458440_1064584700.413.9e-02Click!


Activity profile for motif Barhl2.

activity profile for motif Barhl2


Sorted Z-values histogram for motif Barhl2

Sorted Z-values for motif Barhl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Barhl2

PNG image of the network

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Top targets:


Showing 1 to 20 of 109 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_27153844 1.897 ENSMUST00000176242.2
ENSMUST00000176780.1
 Ect2

ect2 oncogene

chr3_-_27153861 1.853 ENSMUST00000108300.1
ENSMUST00000108298.2
 Ect2

ect2 oncogene

chr3_-_27153782 1.851 ENSMUST00000175857.1
ENSMUST00000177055.1
ENSMUST00000176535.1
 Ect2


ect2 oncogene


chr5_+_110839973 1.749 ENSMUST00000066160.1
 Chek2
checkpoint kinase 2
chr17_+_35439155 1.661 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
 H2-Q7



histocompatibility 2, Q region locus 7



chr11_+_112782182 1.501 ENSMUST00000000579.2
 Sox9
SRY-box containing gene 9
chr13_-_47106176 1.443 ENSMUST00000021807.6
ENSMUST00000135278.1
 Dek

DEK oncogene (DNA binding)

chr7_+_79660196 1.352 ENSMUST00000035977.7
 Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr2_+_59612034 1.345 ENSMUST00000112568.1
ENSMUST00000037526.4
 Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr19_-_6969746 1.123 ENSMUST00000025912.8
 Plcb3
phospholipase C, beta 3
chr6_-_95718800 1.068 ENSMUST00000079847.5
 Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr2_+_31640037 1.060 ENSMUST00000113470.2
 Prdm12
PR domain containing 12
chr3_-_154328634 1.040 ENSMUST00000167744.1
 Lhx8
LIM homeobox protein 8
chr12_+_78748947 1.030 ENSMUST00000082024.5
 Mpp5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr4_-_9643638 1.014 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
 Asph




aspartate-beta-hydroxylase




chr10_+_58394381 1.009 ENSMUST00000105468.1
 Lims1
LIM and senescent cell antigen-like domains 1
chr19_+_25406661 1.005 ENSMUST00000146647.1
 Kank1
KN motif and ankyrin repeat domains 1
chr17_-_25727364 0.998 ENSMUST00000170070.1
ENSMUST00000048054.7
 Chtf18

CTF18, chromosome transmission fidelity factor 18

chr4_+_154960915 0.977 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chr18_-_80986578 0.976 ENSMUST00000057950.7
 Sall3
sal-like 3 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.5 1.8 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.4 1.7 GO:1903463 mitotic cell cycle phase(GO:0098763) regulation of mitotic cell cycle DNA replication(GO:1903463)
0.0 1.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.5 1.5 GO:0035622 intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034)
0.1 1.5 GO:0034453 microtubule anchoring(GO:0034453)
0.4 1.4 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.2 1.4 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174) mitotic DNA replication checkpoint(GO:0033314)
0.1 1.3 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 1.3 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.2 1.1 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.1 1.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 1.1 GO:0009395 phospholipid catabolic process(GO:0009395)
0.3 1.0 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.3 1.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 1.0 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.1 1.0 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 1.0 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 1.0 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 1.0 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 5.6 GO:0097149 centralspindlin complex(GO:0097149)
0.0 2.3 GO:0016605 PML body(GO:0016605)
0.2 2.0 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 1.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.3 1.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 1.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 1.0 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 1.0 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 1.0 GO:0000796 condensin complex(GO:0000796)
0.1 1.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 1.0 GO:0043034 costamere(GO:0043034)
0.0 1.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.5 GO:0033269 internode region of axon(GO:0033269)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.4 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.3 GO:0005687 U4 snRNP(GO:0005687)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 1.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 1.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 1.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 1.1 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.1 1.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.1 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.1 1.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.2 0.9 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 0.9 GO:0005113 patched binding(GO:0005113)
0.1 0.9 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.7 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 0.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)