Motif ID: Bbx

Z-value: 0.385


Transcription factors associated with Bbx:

Gene SymbolEntrez IDGene Name
Bbx ENSMUSG00000022641.9 Bbx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bbxmm10_v2_chr16_-_50330987_50331017-0.525.9e-03Click!


Activity profile for motif Bbx.

activity profile for motif Bbx


Sorted Z-values histogram for motif Bbx

Sorted Z-values for motif Bbx



Network of associatons between targets according to the STRING database.



First level regulatory network of Bbx

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_21111452 2.546 ENSMUST00000075132.6
Cdh12
cadherin 12
chr13_+_49608030 1.871 ENSMUST00000021822.5
Ogn
osteoglycin
chr5_-_146585239 1.845 ENSMUST00000036211.6
Gpr12
G-protein coupled receptor 12
chr13_-_52530827 1.765 ENSMUST00000057442.6
Diras2
DIRAS family, GTP-binding RAS-like 2
chr18_+_37421418 1.251 ENSMUST00000053073.4
Pcdhb11
protocadherin beta 11
chr17_+_57358682 0.878 ENSMUST00000086763.5
ENSMUST00000004850.7
Emr1

EGF-like module containing, mucin-like, hormone receptor-like sequence 1

chr10_+_86021961 0.751 ENSMUST00000130320.1
Fbxo7
F-box protein 7
chr16_+_20693263 0.605 ENSMUST00000149543.1
ENSMUST00000118919.1
Fam131a

family with sequence similarity 131, member A

chrX_-_150814265 0.571 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2


melanoma antigen, family D, 2


chrX_+_159708593 0.568 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr8_+_70616816 0.532 ENSMUST00000052437.3
Lrrc25
leucine rich repeat containing 25
chr8_-_41054771 0.414 ENSMUST00000093534.4
Mtus1
mitochondrial tumor suppressor 1
chrX_+_140367494 0.391 ENSMUST00000141660.1
Frmpd3
FERM and PDZ domain containing 3
chr12_-_86079019 0.379 ENSMUST00000003687.6
Tgfb3
transforming growth factor, beta 3
chr10_-_86022325 0.362 ENSMUST00000181665.1
A230060F14Rik
RIKEN cDNA A230060F14 gene
chr1_+_180111339 0.288 ENSMUST00000145181.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr10_+_84622365 0.145 ENSMUST00000077175.5
Polr3b
polymerase (RNA) III (DNA directed) polypeptide B
chrX_-_107816238 0.141 ENSMUST00000120722.1
2610002M06Rik
RIKEN cDNA 2610002M06 gene
chr12_+_103388656 0.111 ENSMUST00000101094.2
ENSMUST00000021620.6
Otub2

OTU domain, ubiquitin aldehyde binding 2

chr2_+_136892168 0.099 ENSMUST00000099311.2
Slx4ip
SLX4 interacting protein
chr2_-_152830615 0.093 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
Bcl2l1



BCL2-like 1



chr6_+_124304646 0.030 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chr5_-_108675569 0.022 ENSMUST00000051757.7
Slc26a1
solute carrier family 26 (sulfate transporter), member 1
chr7_-_127708886 0.004 ENSMUST00000061468.8
Bcl7c
B cell CLL/lymphoma 7C

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003032 detection of oxygen(GO:0003032) regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.1 GO:0046898 response to cycloheximide(GO:0046898)
0.0 0.7 GO:0045620 negative regulation of lymphocyte differentiation(GO:0045620)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 1.9 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)