Motif ID: Bcl6b

Z-value: 0.524


Transcription factors associated with Bcl6b:

Gene SymbolEntrez IDGene Name
Bcl6b ENSMUSG00000000317.5 Bcl6b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl6bmm10_v2_chr11_-_70229677_702297610.301.4e-01Click!


Activity profile for motif Bcl6b.

activity profile for motif Bcl6b


Sorted Z-values histogram for motif Bcl6b

Sorted Z-values for motif Bcl6b



Network of associatons between targets according to the STRING database.



First level regulatory network of Bcl6b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_64046925 3.164 ENSMUST00000107377.3
 Tnc
tenascin C
chr16_-_74411292 1.530 ENSMUST00000117200.1
 Robo2
roundabout homolog 2 (Drosophila)
chr16_-_74411776 1.299 ENSMUST00000116586.2
 Robo2
roundabout homolog 2 (Drosophila)
chr1_-_173942445 0.986 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
 Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr13_-_98815408 0.938 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
 Fcho2



FCH domain only 2



chr19_-_5797410 0.909 ENSMUST00000173314.1
 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chrX_+_151344171 0.868 ENSMUST00000073364.5
 Fam120c
family with sequence similarity 120, member C
chr9_-_112232449 0.787 ENSMUST00000035085.5
 Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr10_+_57794335 0.766 ENSMUST00000151623.1
ENSMUST00000020022.7
 Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

chr2_+_119594288 0.762 ENSMUST00000147425.1
ENSMUST00000153581.1
 1700020I14Rik

RIKEN cDNA 1700020I14 gene

chr18_-_78123324 0.726 ENSMUST00000160292.1
ENSMUST00000091813.5
 Slc14a1

solute carrier family 14 (urea transporter), member 1

chr10_-_95417099 0.666 ENSMUST00000135822.1
 Socs2
suppressor of cytokine signaling 2
chr10_-_95416850 0.639 ENSMUST00000020215.9
 Socs2
suppressor of cytokine signaling 2
chr5_-_150665315 0.639 ENSMUST00000141857.1
 N4bp2l2
NEDD4 binding protein 2-like 2
chr8_+_13907748 0.605 ENSMUST00000043520.3
 Fbxo25
F-box protein 25
chr6_+_149309391 0.552 ENSMUST00000130664.1
ENSMUST00000046689.6
 2810474O19Rik

RIKEN cDNA 2810474O19 gene

chr9_+_40269430 0.538 ENSMUST00000171835.2
 Scn3b
sodium channel, voltage-gated, type III, beta
chr6_+_149309444 0.536 ENSMUST00000100765.4
 2810474O19Rik
RIKEN cDNA 2810474O19 gene
chr10_+_81633694 0.524 ENSMUST00000140345.1
ENSMUST00000126323.1
 Ankrd24

ankyrin repeat domain 24

chr12_-_40134175 0.512 ENSMUST00000078481.7
ENSMUST00000002640.5
 Scin

scinderin

chr10_-_86705485 0.502 ENSMUST00000020238.7
 Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr5_-_123140135 0.458 ENSMUST00000160099.1
 AI480526
expressed sequence AI480526
chr2_-_180824596 0.428 ENSMUST00000148700.1
 Gm14340
predicted gene 14340
chr16_-_34263179 0.408 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chr11_+_70764209 0.404 ENSMUST00000060444.5
 Zfp3
zinc finger protein 3
chr15_-_93519499 0.388 ENSMUST00000109255.2
 Prickle1
prickle homolog 1 (Drosophila)
chr5_-_150665560 0.380 ENSMUST00000118316.1
 N4bp2l2
NEDD4 binding protein 2-like 2
chr18_+_33794915 0.365 ENSMUST00000179138.1
 2410004N09Rik
RIKEN cDNA 2410004N09 gene
chr9_-_90255927 0.355 ENSMUST00000144646.1
 Tbc1d2b
TBC1 domain family, member 2B
chr1_+_139454747 0.354 ENSMUST00000053364.8
ENSMUST00000097554.3
 Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr3_+_55242526 0.320 ENSMUST00000054237.7
ENSMUST00000167204.1
 Dclk1

doublecortin-like kinase 1

chr16_-_34262830 0.314 ENSMUST00000114947.1
 Kalrn
kalirin, RhoGEF kinase
chr9_+_107296843 0.302 ENSMUST00000167072.1
 Cish
cytokine inducible SH2-containing protein
chr16_-_34262945 0.273 ENSMUST00000114953.1
 Kalrn
kalirin, RhoGEF kinase
chr2_-_65567465 0.270 ENSMUST00000066432.5
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr9_+_86743641 0.251 ENSMUST00000179574.1
 Prss35
protease, serine, 35
chr7_+_43579577 0.237 ENSMUST00000058104.7
 Zfp719
zinc finger protein 719
chr2_-_65567505 0.227 ENSMUST00000100069.2
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr6_+_106769120 0.224 ENSMUST00000113247.1
ENSMUST00000113249.1
ENSMUST00000057578.9
ENSMUST00000113248.1
 Trnt1



tRNA nucleotidyl transferase, CCA-adding, 1



chr9_-_95815389 0.224 ENSMUST00000119760.1
 Pls1
plastin 1 (I-isoform)
chr18_+_37320374 0.221 ENSMUST00000078271.2
 Pcdhb5
protocadherin beta 5
chr2_+_131133497 0.211 ENSMUST00000110225.1
 Gm11037
predicted gene 11037
chr17_-_45592569 0.207 ENSMUST00000163492.1
 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr9_+_86743616 0.203 ENSMUST00000036426.6
 Prss35
protease, serine, 35
chr3_+_95588990 0.200 ENSMUST00000177399.1
 Golph3l
golgi phosphoprotein 3-like
chr18_+_42275353 0.191 ENSMUST00000046972.7
ENSMUST00000091920.5
 Rbm27

RNA binding motif protein 27

chr3_+_84925476 0.175 ENSMUST00000107675.1
 Fbxw7
F-box and WD-40 domain protein 7
chr3_-_96240317 0.153 ENSMUST00000078756.5
 Hist2h2aa2
histone cluster 2, H2aa2
chrX_+_153359613 0.151 ENSMUST00000039545.4
 Klf8
Kruppel-like factor 8
chr11_+_95712673 0.145 ENSMUST00000107717.1
 Zfp652
zinc finger protein 652
chr6_-_128355826 0.140 ENSMUST00000001562.6
 Tulp3
tubby-like protein 3
chr17_-_45592485 0.117 ENSMUST00000166119.1
 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr1_+_191717834 0.115 ENSMUST00000110855.1
ENSMUST00000133076.1
 Lpgat1

lysophosphatidylglycerol acyltransferase 1

chr3_+_95588960 0.107 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
 Golph3l


golgi phosphoprotein 3-like


chr7_+_48789003 0.098 ENSMUST00000118927.1
ENSMUST00000125280.1
 Zdhhc13

zinc finger, DHHC domain containing 13

chr3_+_95588928 0.086 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
 Golph3l


golgi phosphoprotein 3-like


chr4_+_3574872 0.082 ENSMUST00000052712.5
 Tgs1
trimethylguanosine synthase homolog (S. cerevisiae)
chr2_-_77946331 0.079 ENSMUST00000111821.2
ENSMUST00000111818.1
 Cwc22

CWC22 spliceosome-associated protein homolog (S. cerevisiae)

chr9_+_107296682 0.071 ENSMUST00000168260.1
 Cish
cytokine inducible SH2-containing protein
chr1_+_83159733 0.065 ENSMUST00000113436.1
ENSMUST00000065436.3
ENSMUST00000065403.6
 Daw1


dynein assembly factor with WDR repeat domains 1


chr13_-_76018524 0.065 ENSMUST00000050997.1
ENSMUST00000179078.1
ENSMUST00000167271.1
 Rfesd


Rieske (Fe-S) domain containing


chr4_+_149485260 0.055 ENSMUST00000030842.7
 Lzic
leucine zipper and CTNNBIP1 domain containing
chr9_+_121938099 0.046 ENSMUST00000063103.4
 1700048O20Rik
RIKEN cDNA 1700048O20 gene
chr2_-_77946375 0.045 ENSMUST00000065889.3
 Cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr8_+_25601591 0.043 ENSMUST00000155861.1
 Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr5_-_123721007 0.039 ENSMUST00000031376.7
 Zcchc8
zinc finger, CCHC domain containing 8
chr8_+_27042555 0.039 ENSMUST00000033875.8
ENSMUST00000098851.4
 Prosc

proline synthetase co-transcribed

chr3_+_84593547 0.036 ENSMUST00000062623.3
 Tigd4
tigger transposable element derived 4
chr15_+_25752860 0.034 ENSMUST00000022882.5
ENSMUST00000135173.1
 Myo10

myosin X

chrX_-_43274786 0.017 ENSMUST00000016294.7
 Tenm1
teneurin transmembrane protein 1
chr9_+_56994932 0.007 ENSMUST00000034832.6
 Ptpn9
protein tyrosine phosphatase, non-receptor type 9
chr15_-_94404258 0.004 ENSMUST00000035342.4
ENSMUST00000155907.1
 Adamts20

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20

chrX_+_74429671 0.003 ENSMUST00000114127.1
ENSMUST00000064407.3
ENSMUST00000156707.1
 Ikbkg


inhibitor of kappaB kinase gamma


chr4_+_155562348 0.003 ENSMUST00000030939.7
 Nadk
NAD kinase
chr6_+_29361410 0.002 ENSMUST00000156163.1
 Calu
calumenin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.8 3.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.3 1.0 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 0.9 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.4 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.1 1.0 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.7 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.1 0.5 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.5 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.1 0.2 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.1 0.5 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 1.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.5 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.3 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.0 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.8 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.8 GO:0030673 axolemma(GO:0030673)
0.1 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.9 GO:0005905 clathrin-coated pit(GO:0005905)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0045545 syndecan binding(GO:0045545)
0.4 2.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 1.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.7 GO:0015265 urea channel activity(GO:0015265)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.5 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.3 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)