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• Activity deltas table
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Motif ID: Brca1

Z-value: 0.716

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_-_23248264	6.590	ENSMUST00000031709.5	Fezf1	Fez family zinc finger 1
chr19_+_55741810	2.299	ENSMUST00000111657.3 ENSMUST00000061496.9 ENSMUST00000041717.7 ENSMUST00000111662.4	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box
chr11_+_44617310	2.216	ENSMUST00000081265.5 ENSMUST00000101326.3 ENSMUST00000109268.1	Ebf1	early B cell factor 1
chr7_-_144939823	2.149	ENSMUST00000093962.4	Ccnd1	cyclin D1
chr2_-_28916668	1.609	ENSMUST00000113847.1	Barhl1	BarH-like 1 (Drosophila)
chr1_-_75278345	1.590	ENSMUST00000039534.4	Resp18	regulated endocrine-specific protein 18
chr17_-_70853482	1.460	ENSMUST00000118283.1	Tgif1	TGFB-induced factor homeobox 1
chr11_-_11890368	1.455	ENSMUST00000155690.1	Ddc	dopa decarboxylase
chr10_-_42583628	1.276	ENSMUST00000019938.4	Nr2e1	nuclear receptor subfamily 2, group E, member 1
chr19_-_24225015	1.253	ENSMUST00000099558.4	Tjp2	tight junction protein 2
chr2_-_105399286	1.203	ENSMUST00000006128.6	Rcn1	reticulocalbin 1
chr3_+_87906321	1.172	ENSMUST00000005017.8	Hdgf	hepatoma-derived growth factor
chr2_-_9883993	1.152	ENSMUST00000114915.2	9230102O04Rik	RIKEN cDNA 9230102O04 gene
chr12_-_10900296	1.026	ENSMUST00000085735.2	Pgk1-rs7	phosphoglycerate kinase-1, related sequence-7
chr18_-_47333311	0.989	ENSMUST00000126684.1 ENSMUST00000156422.1	Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr11_-_106998483	0.979	ENSMUST00000124541.1	Kpna2	karyopherin (importin) alpha 2
chr13_-_95891905	0.966	ENSMUST00000068603.6	Iqgap2	IQ motif containing GTPase activating protein 2
chr11_+_59306920	0.948	ENSMUST00000000128.3 ENSMUST00000108783.3	Wnt9a	wingless-type MMTV integration site 9A
chr5_-_21701332	0.907	ENSMUST00000115217.1 ENSMUST00000060899.8	Napepld	N-acyl phosphatidylethanolamine phospholipase D
chrX_+_71663665	0.903	ENSMUST00000070449.5	Gpr50	G-protein-coupled receptor 50
chr3_+_5218546	0.891	ENSMUST00000026284.6	Zfhx4	zinc finger homeodomain 4
chr3_+_5218516	0.886	ENSMUST00000175866.1	Zfhx4	zinc finger homeodomain 4
chr7_-_102100227	0.885	ENSMUST00000106937.1	Art5	ADP-ribosyltransferase 5
chr13_-_98891036	0.853	ENSMUST00000109399.2	Tnpo1	transportin 1
chr16_+_30065333	0.776	ENSMUST00000023171.7	Hes1	hairy and enhancer of split 1 (Drosophila)
chr3_+_5218589	0.771	ENSMUST00000177488.1	Zfhx4	zinc finger homeodomain 4
chr12_-_69159109	0.732	ENSMUST00000037023.8	Rps29	ribosomal protein S29
chr12_+_52097737	0.715	ENSMUST00000040090.9	Nubpl	nucleotide binding protein-like
chr9_-_37657189	0.708	ENSMUST00000117654.1	Tbrg1	transforming growth factor beta regulated gene 1
chr11_-_98625661	0.708	ENSMUST00000104933.1	Gm12355	predicted gene 12355
chr19_-_10203880	0.707	ENSMUST00000142241.1 ENSMUST00000116542.2 ENSMUST00000025651.5 ENSMUST00000156291.1	Fen1	flap structure specific endonuclease 1
chr6_+_14901344	0.687	ENSMUST00000115477.1	Foxp2	forkhead box P2
chr13_+_24943144	0.678	ENSMUST00000021773.5	Gpld1	glycosylphosphatidylinositol specific phospholipase D1
chr13_-_98890974	0.672	ENSMUST00000179301.1 ENSMUST00000179271.1	Tnpo1	transportin 1
chr5_+_138187485	0.670	ENSMUST00000110934.2	Cnpy4	canopy 4 homolog (zebrafish)
chr1_+_74791516	0.640	ENSMUST00000006718.8	Wnt10a	wingless related MMTV integration site 10a
chr13_-_100775844	0.639	ENSMUST00000075550.3	Cenph	centromere protein H
chrX_+_169685191	0.632	ENSMUST00000112104.1 ENSMUST00000112107.1	Mid1	midline 1
chr9_-_109082372	0.618	ENSMUST00000167504.1	Tma7	translational machinery associated 7 homolog (S. cerevisiae)
chr6_-_120357342	0.593	ENSMUST00000163827.1	Ccdc77	coiled-coil domain containing 77
chr5_+_146832890	0.586	ENSMUST00000035983.5	Rpl21	ribosomal protein L21
chr3_+_109573907	0.585	ENSMUST00000106576.2	Vav3	vav 3 oncogene
chr3_-_138131356	0.572	ENSMUST00000029805.8	Mttp	microsomal triglyceride transfer protein
chr17_-_6655939	0.565	ENSMUST00000179554.1	Dynlt1f	dynein light chain Tctex-type 1F
chrX_+_150594420	0.565	ENSMUST00000112713.2	Pfkfb1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr5_-_138187177	0.558	ENSMUST00000110937.1 ENSMUST00000139276.1 ENSMUST00000048698.7 ENSMUST00000123415.1	Taf6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr8_-_47990535	0.545	ENSMUST00000057561.7	Wwc2	WW, C2 and coiled-coil domain containing 2
chr5_+_146833106	0.532	ENSMUST00000075453.2 ENSMUST00000099272.2	Rpl21	ribosomal protein L21
chr19_-_32466575	0.532	ENSMUST00000078034.3	Rpl9-ps6	ribosomal protein L9, pseudogene 6
chr7_-_44375006	0.523	ENSMUST00000107933.1	1700008O03Rik	RIKEN cDNA 1700008O03 gene
chr13_-_107890059	0.520	ENSMUST00000105097.2	Zswim6	zinc finger SWIM-type containing 6
chr18_+_7869707	0.518	ENSMUST00000166062.1 ENSMUST00000169010.1	Wac	WW domain containing adaptor with coiled-coil
chr10_-_33624587	0.517	ENSMUST00000160299.1 ENSMUST00000019920.6	Clvs2	clavesin 2
chrX_-_101222426	0.513	ENSMUST00000120389.1 ENSMUST00000156473.1 ENSMUST00000077876.3	Snx12	sorting nexin 12
chr6_-_120357440	0.512	ENSMUST00000112703.1	Ccdc77	coiled-coil domain containing 77
chr14_-_67715585	0.509	ENSMUST00000163100.1 ENSMUST00000132705.1 ENSMUST00000124045.1	Cdca2	cell division cycle associated 2
chr1_-_46854046	0.508	ENSMUST00000027131.4	Slc39a10	solute carrier family 39 (zinc transporter), member 10
chr3_-_100489324	0.498	ENSMUST00000061455.8	Fam46c	family with sequence similarity 46, member C
chr13_+_100651328	0.498	ENSMUST00000084721.6 ENSMUST00000022135.8	Taf9 Taf9	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr5_-_135064063	0.493	ENSMUST00000111205.1 ENSMUST00000141309.1	Wbscr22	Williams Beuren syndrome chromosome region 22
chr17_-_34028044	0.489	ENSMUST00000045467.7 ENSMUST00000114303.3	H2-Ke6	H2-K region expressed gene 6
chr15_-_97020322	0.484	ENSMUST00000166223.1	Slc38a4	solute carrier family 38, member 4
chr17_-_33685386	0.478	ENSMUST00000139302.1 ENSMUST00000087582.5 ENSMUST00000114385.2	Hnrnpm	heterogeneous nuclear ribonucleoprotein M
chr6_-_120357422	0.477	ENSMUST00000032283.5	Ccdc77	coiled-coil domain containing 77
chr17_-_28350747	0.471	ENSMUST00000080572.7 ENSMUST00000156862.1	Tead3	TEA domain family member 3
chr19_+_36083696	0.471	ENSMUST00000025714.7	Rpp30	ribonuclease P/MRP 30 subunit
chr7_+_51878967	0.461	ENSMUST00000051912.6	Gas2	growth arrest specific 2
chrX_+_150589907	0.458	ENSMUST00000080884.4	Pfkfb1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr7_-_133122615	0.453	ENSMUST00000167218.1	Ctbp2	C-terminal binding protein 2
chr19_+_44562841	0.442	ENSMUST00000040455.4	Hif1an	hypoxia-inducible factor 1, alpha subunit inhibitor
chr3_+_87930256	0.442	ENSMUST00000055984.6	Isg20l2	interferon stimulated exonuclease gene 20-like 2
chr7_+_101896817	0.432	ENSMUST00000143835.1	Anapc15	anaphase prompoting complex C subunit 15
chr4_-_41464816	0.430	ENSMUST00000108055.2 ENSMUST00000154535.1 ENSMUST00000030148.5	Kif24	kinesin family member 24
chr4_-_116708312	0.423	ENSMUST00000030453.4	Mmachc	methylmalonic aciduria cblC type, with homocystinuria
chr7_-_102099932	0.422	ENSMUST00000106934.1	Art5	ADP-ribosyltransferase 5
chr8_-_11008458	0.417	ENSMUST00000040514.6	Irs2	insulin receptor substrate 2
chr6_-_125191535	0.411	ENSMUST00000043848.4	Ncapd2	non-SMC condensin I complex, subunit D2
chr15_+_102460076	0.407	ENSMUST00000164688.1	Prr13	proline rich 13
chr17_+_71204647	0.405	ENSMUST00000126681.1	Lpin2	lipin 2
chr6_+_116264186	0.402	ENSMUST00000036503.7 ENSMUST00000112900.3	Zfand4	zinc finger, AN1-type domain 4
chr10_-_128923439	0.401	ENSMUST00000153731.1 ENSMUST00000026405.3	Bloc1s1	biogenesis of lysosome-related organelles complex-1, subunit 1
chr17_+_6430112	0.395	ENSMUST00000179569.1	Dynlt1b	dynein light chain Tctex-type 1B
chr6_-_122340499	0.373	ENSMUST00000160843.1	Phc1	polyhomeotic-like 1 (Drosophila)
chr10_-_13388830	0.370	ENSMUST00000079698.5	Phactr2	phosphatase and actin regulator 2
chr17_-_28350600	0.363	ENSMUST00000114799.1	Tead3	TEA domain family member 3
chr4_-_131838231	0.361	ENSMUST00000030741.2 ENSMUST00000105987.2	Ptpru	protein tyrosine phosphatase, receptor type, U
chr2_-_25224653	0.361	ENSMUST00000043584.4	Tubb4b	tubulin, beta 4B class IVB
chr5_-_115158169	0.354	ENSMUST00000053271.5 ENSMUST00000112121.1	Mlec	malectin
chr11_-_101171302	0.353	ENSMUST00000164474.1 ENSMUST00000043397.7	Plekhh3	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr7_-_17027853	0.341	ENSMUST00000003183.5	Ppp5c	protein phosphatase 5, catalytic subunit
chr18_-_15063560	0.336	ENSMUST00000168989.1	Kctd1	potassium channel tetramerisation domain containing 1
chr10_-_128923948	0.333	ENSMUST00000131271.1	Bloc1s1	biogenesis of lysosome-related organelles complex-1, subunit 1
chr10_-_13388753	0.333	ENSMUST00000105546.1	Phactr2	phosphatase and actin regulator 2
chr7_-_64872993	0.322	ENSMUST00000094331.2	Ndnl2	necdin-like 2
chr17_+_35841668	0.322	ENSMUST00000174124.1	Mdc1	mediator of DNA damage checkpoint 1
chr19_-_12765447	0.319	ENSMUST00000112933.1	Cntf	ciliary neurotrophic factor
chr8_+_25017211	0.318	ENSMUST00000033961.5	Tm2d2	TM2 domain containing 2
chr17_+_35841491	0.314	ENSMUST00000082337.6	Mdc1	mediator of DNA damage checkpoint 1
chr5_+_136953246	0.313	ENSMUST00000111094.1 ENSMUST00000111097.1	Fis1	fission 1 (mitochondrial outer membrane) homolog (yeast)
chr14_-_52305056	0.303	ENSMUST00000174853.1 ENSMUST00000022767.9	Mettl3	methyltransferase like 3
chr2_-_58052832	0.299	ENSMUST00000090940.5	Ermn	ermin, ERM-like protein
chr19_+_6047081	0.290	ENSMUST00000025723.8	Syvn1	synovial apoptosis inhibitor 1, synoviolin
chr11_+_6291660	0.286	ENSMUST00000101554.2 ENSMUST00000093350.3	Ogdh	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr3_-_95882031	0.286	ENSMUST00000161994.1	Gm129	predicted gene 129
chr16_+_22009471	0.274	ENSMUST00000023561.7	Senp2	SUMO/sentrin specific peptidase 2
chr11_+_6291607	0.267	ENSMUST00000003461.8	Ogdh	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chrM_+_9452	0.260	ENSMUST00000082411.1	mt-Nd3	mitochondrially encoded NADH dehydrogenase 3
chr15_-_34443508	0.259	ENSMUST00000079735.5	Rpl30	ribosomal protein L30
chr4_+_148000722	0.250	ENSMUST00000103230.4	Nppa	natriuretic peptide type A
chr6_-_122340525	0.244	ENSMUST00000112600.2	Phc1	polyhomeotic-like 1 (Drosophila)
chr11_+_97703394	0.243	ENSMUST00000103147.4	Psmb3	proteasome (prosome, macropain) subunit, beta type 3
chr4_+_100776664	0.238	ENSMUST00000030257.8 ENSMUST00000097955.2	Cachd1	cache domain containing 1
chr1_+_135729147	0.235	ENSMUST00000027677.7	Csrp1	cysteine and glycine-rich protein 1
chr17_+_8165501	0.233	ENSMUST00000097419.3 ENSMUST00000024636.8	Fgfr1op	Fgfr1 oncogene partner
chr2_-_34870921	0.229	ENSMUST00000028225.5	Psmd5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
chr3_+_96172327	0.228	ENSMUST00000076372.4	Sf3b4	splicing factor 3b, subunit 4
chr7_-_17027807	0.226	ENSMUST00000142597.1	Ppp5c	protein phosphatase 5, catalytic subunit
chr13_+_100651607	0.224	ENSMUST00000167256.1	Taf9	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr19_+_45560569	0.223	ENSMUST00000047057.7	Dpcd	deleted in primary ciliary dyskinesia
chr14_-_54864055	0.216	ENSMUST00000142283.2	Homez	homeodomain leucine zipper-encoding gene
chr4_+_10874498	0.214	ENSMUST00000080517.7 ENSMUST00000101504.2	2610301B20Rik	RIKEN cDNA 2610301B20 gene
chr3_-_127553233	0.213	ENSMUST00000029588.5	Larp7	La ribonucleoprotein domain family, member 7
chr1_-_171281181	0.206	ENSMUST00000073120.4	Ppox	protoporphyrinogen oxidase
chr15_+_10952332	0.199	ENSMUST00000022853.8 ENSMUST00000110523.1	C1qtnf3	C1q and tumor necrosis factor related protein 3
chr3_-_51277470	0.198	ENSMUST00000108053.2 ENSMUST00000108051.1	Elf2	E74-like factor 2
chr19_-_7295394	0.193	ENSMUST00000025921.8	Mark2	MAP/microtubule affinity-regulating kinase 2
chr12_+_87266696	0.189	ENSMUST00000021425.6	Ahsa1	AHA1, activator of heat shock protein ATPase 1
chr1_+_192190771	0.189	ENSMUST00000078470.5 ENSMUST00000110844.1	Kcnh1	potassium voltage-gated channel, subfamily H (eag-related), member 1
chr17_-_47611449	0.188	ENSMUST00000024783.8	Bysl	bystin-like
chr7_-_80947765	0.184	ENSMUST00000026818.5 ENSMUST00000117383.1 ENSMUST00000119980.1	Sec11a	SEC11 homolog A (S. cerevisiae)
chr2_+_174330006	0.180	ENSMUST00000109085.1 ENSMUST00000109087.1 ENSMUST00000109084.1	Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr12_-_108894116	0.171	ENSMUST00000109848.3	Wars	tryptophanyl-tRNA synthetase
chrX_-_150589844	0.166	ENSMUST00000112725.1 ENSMUST00000112720.1	Apex2	apurinic/apyrimidinic endonuclease 2
chr1_+_182124737	0.163	ENSMUST00000111018.1 ENSMUST00000027792.5	Srp9	signal recognition particle 9
chr1_-_33814591	0.163	ENSMUST00000019861.6	Zfp451	zinc finger protein 451
chrM_+_8600	0.163	ENSMUST00000082409.1	mt-Co3	mitochondrially encoded cytochrome c oxidase III
chr2_+_167932327	0.162	ENSMUST00000029053.7	Ptpn1	protein tyrosine phosphatase, non-receptor type 1
chr7_-_80947499	0.161	ENSMUST00000120285.1	Sec11a	SEC11 homolog A (S. cerevisiae)
chr3_-_90433603	0.156	ENSMUST00000029542.5 ENSMUST00000071488.3	Ints3	integrator complex subunit 3
chr9_+_44773191	0.155	ENSMUST00000147559.1	Ift46	intraflagellar transport 46
chr7_-_19715395	0.154	ENSMUST00000032555.9 ENSMUST00000093552.5	Tomm40	translocase of outer mitochondrial membrane 40 homolog (yeast)
chr1_+_172148015	0.152	ENSMUST00000074144.5	Dcaf8	DDB1 and CUL4 associated factor 8
chr15_-_82016134	0.149	ENSMUST00000152227.1	Desi1	desumoylating isopeptidase 1
chr8_-_107263248	0.143	ENSMUST00000080443.6	Rps18-ps3	ribosomal protein S18, pseudogene 3
chr12_-_110695860	0.140	ENSMUST00000149189.1	Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1
chr17_+_7945653	0.135	ENSMUST00000097423.2	Rsph3a	radial spoke 3A homolog (Chlamydomonas)
chr12_-_99393010	0.129	ENSMUST00000177451.1	Foxn3	forkhead box N3
chr3_-_158031705	0.117	ENSMUST00000072875.8	Srsf11	serine/arginine-rich splicing factor 11
chr5_-_123666682	0.115	ENSMUST00000149410.1	Clip1	CAP-GLY domain containing linker protein 1
chr2_-_155582656	0.115	ENSMUST00000126322.1	Gss	glutathione synthetase
chr5_+_147077050	0.109	ENSMUST00000050970.3	Polr1d	polymerase (RNA) I polypeptide D
chr12_+_108894272	0.101	ENSMUST00000167816.1 ENSMUST00000047115.7	Wdr25	WD repeat domain 25
chr3_-_95882232	0.099	ENSMUST00000161866.1	Gm129	predicted gene 129
chr17_-_15498263	0.089	ENSMUST00000014913.9	Psmb1	proteasome (prosome, macropain) subunit, beta type 1
chr12_+_4082574	0.082	ENSMUST00000020986.7	Dnajc27	DnaJ (Hsp40) homolog, subfamily C, member 27
chr16_-_11066141	0.081	ENSMUST00000162323.1	Litaf	LPS-induced TN factor
chr1_+_66386968	0.081	ENSMUST00000145419.1	Map2	microtubule-associated protein 2
chr9_+_59589288	0.074	ENSMUST00000121266.1 ENSMUST00000118164.1	Celf6	CUGBP, Elav-like family member 6
chr7_-_35056467	0.074	ENSMUST00000130491.1	Cebpg	CCAAT/enhancer binding protein (C/EBP), gamma
chr15_-_27681498	0.070	ENSMUST00000100739.3	Fam105a	family with sequence similarity 105, member A
chr6_+_100833606	0.066	ENSMUST00000063854.4	Ppp4r2	protein phosphatase 4, regulatory subunit 2
chr18_+_36793918	0.064	ENSMUST00000001419.8	Zmat2	zinc finger, matrin type 2
chr4_-_98817537	0.062	ENSMUST00000102790.3	Kank4	KN motif and ankyrin repeat domains 4
chr4_+_133176336	0.060	ENSMUST00000105912.1	Wasf2	WAS protein family, member 2
chr2_-_152831665	0.060	ENSMUST00000156688.1 ENSMUST00000007803.5	Bcl2l1	BCL2-like 1
chr18_+_42275353	0.053	ENSMUST00000046972.7 ENSMUST00000091920.5	Rbm27	RNA binding motif protein 27
chr11_+_70970467	0.039	ENSMUST00000178822.1 ENSMUST00000108529.3 ENSMUST00000169965.1 ENSMUST00000167509.1	Rpain	RPA interacting protein
chr17_-_6961156	0.038	ENSMUST00000063683.6	Tagap1	T cell activation GTPase activating protein 1
chr17_+_33909481	0.037	ENSMUST00000173626.1 ENSMUST00000174541.1	Daxx	Fas death domain-associated protein
chrX_-_64276937	0.035	ENSMUST00000114679.1 ENSMUST00000069926.7	Slitrk4	SLIT and NTRK-like family, member 4
chr12_+_103388656	0.034	ENSMUST00000101094.2 ENSMUST00000021620.6	Otub2	OTU domain, ubiquitin aldehyde binding 2
chr3_-_88951146	0.032	ENSMUST00000173135.1	Dap3	death associated protein 3
chr4_+_43632185	0.027	ENSMUST00000107874.2	Npr2	natriuretic peptide receptor 2
chr2_-_91183017	0.017	ENSMUST00000066420.5	Madd	MAP-kinase activating death domain
chr17_+_40811089	0.014	ENSMUST00000024721.7	Rhag	Rhesus blood group-associated A glycoprotein
chr1_+_87326997	0.013	ENSMUST00000027475.8	Gigyf2	GRB10 interacting GYF protein 2
chr8_+_84872105	0.010	ENSMUST00000136026.1 ENSMUST00000170296.1	Syce2	synaptonemal complex central element protein 2
chr2_-_91182848	0.006	ENSMUST00000111370.2 ENSMUST00000111376.1 ENSMUST00000099723.2	Madd	MAP-kinase activating death domain

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	6.6	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.3	1.3	GO:1903011	negative regulation of bone development(GO:1903011)
0.3	2.1	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
0.3	2.3	GO:0048625	myoblast fate commitment(GO:0048625)
0.3	0.8	GO:0021557	oculomotor nerve development(GO:0021557) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.3	1.3	GO:0021764	amygdala development(GO:0021764)
0.2	1.5	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2	0.7	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.2	0.9	GO:1903998	regulation of eating behavior(GO:1903998)
0.2	0.7	GO:0010986	complement receptor mediated signaling pathway(GO:0002430) GPI anchor release(GO:0006507) positive regulation of lipoprotein particle clearance(GO:0010986)
0.2	0.5	GO:2000642	negative regulation of early endosome to late endosome transport(GO:2000642)
0.1	0.4	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1	1.5	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	1.0	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	1.0	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.1	0.7	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.1	0.6	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1	0.5	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.1	0.7	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.1	0.9	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.1	1.5	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.4	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1	0.2	GO:0097623	potassium ion export across plasma membrane(GO:0097623)
0.1	0.4	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.1	0.6	GO:0016576	histone dephosphorylation(GO:0016576)
0.1	0.2	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.1	0.2	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.1	0.8	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.1	0.5	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	0.3	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668) astrocyte activation(GO:0048143) regulation of resting membrane potential(GO:0060075)
0.1	0.6	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	1.0	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.1	0.3	GO:1904690	adenosine to inosine editing(GO:0006382) regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1	0.6	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1	0.7	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1	0.2	GO:0006436	tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1	0.5	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1	0.2	GO:0021678	third ventricle development(GO:0021678)
0.1	0.3	GO:0009235	cobalamin metabolic process(GO:0009235)
0.1	1.3	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.1	0.2	GO:2000616	negative regulation of histone H3-K9 acetylation(GO:2000616)
0.0	0.2	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	1.0	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	0.5	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.0	0.6	GO:0051383	kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.0	0.2	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.9	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	1.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	1.6	GO:0030901	midbrain development(GO:0030901)
0.0	0.7	GO:0099517	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	0.2	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.0	0.2	GO:0071638	cellular triglyceride homeostasis(GO:0035356) adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0	0.1	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0044861	protein transport into plasma membrane raft(GO:0044861)
0.0	0.6	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.1	GO:0045204	MAPK export from nucleus(GO:0045204)
0.0	0.1	GO:0045583	regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0	0.5	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.5	GO:2001222	regulation of neuron migration(GO:2001222)
0.0	0.2	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.3	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.6	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.4	GO:0019432	triglyceride biosynthetic process(GO:0019432)
0.0	1.1	GO:0007019	microtubule depolymerization(GO:0007019)
0.0	0.6	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.0	0.5	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.2	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.3	GO:0001763	morphogenesis of a branching structure(GO:0001763)
0.0	0.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.2	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.3	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0	0.1	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0043540	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.3	1.6	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.3	2.3	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.1	0.7	GO:0000125	PCAF complex(GO:0000125)
0.1	0.3	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.1	0.6	GO:1990635	proximal dendrite(GO:1990635)
0.1	0.5	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.1	0.6	GO:0001739	sex chromatin(GO:0001739)
0.1	0.5	GO:0042382	paraspeckles(GO:0042382)
0.1	0.4	GO:0000796	condensin complex(GO:0000796)
0.1	0.6	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.1	0.2	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.1	0.2	GO:0097443	sorting endosome(GO:0097443)
0.0	1.3	GO:0005921	gap junction(GO:0005921)
0.0	2.1	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.3	GO:0036396	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0	0.6	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.7	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.3	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	0.6	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.7	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.3	GO:0033269	internode region of axon(GO:0033269)
0.0	0.4	GO:0045298	tubulin complex(GO:0045298)
0.0	0.2	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.2	GO:0042629	mast cell granule(GO:0042629)
0.0	0.2	GO:0070876	SOSS complex(GO:0070876)
0.0	0.1	GO:0097226	sperm mitochondrial sheath(GO:0097226)
0.0	0.5	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.3	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	1.0	GO:0031941	filamentous actin(GO:0031941)
0.0	1.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.2	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	1.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.5	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.3	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.7	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	1.2	GO:0005643	nuclear pore(GO:0005643)
0.0	0.1	GO:0030289	protein phosphatase 4 complex(GO:0030289)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.3	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.4	1.5	GO:0036468	aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.3	0.7	GO:0004630	phospholipase D activity(GO:0004630)
0.3	0.9	GO:0008502	melatonin receptor activity(GO:0008502)
0.2	2.9	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.2	0.6	GO:0043515	kinetochore binding(GO:0043515)
0.1	1.0	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.1	0.7	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.1	0.4	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	0.4	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	2.3	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	1.0	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	0.6	GO:0034602	oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1	0.3	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1	2.1	GO:0070064	proline-rich region binding(GO:0070064)
0.1	2.3	GO:0008432	JUN kinase binding(GO:0008432)
0.1	2.5	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	0.5	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1	0.4	GO:0031419	cobalamin binding(GO:0031419)
0.1	0.2	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.5	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.2	GO:0004830	tryptophan-tRNA ligase activity(GO:0004830)
0.1	1.1	GO:0001222	transcription corepressor binding(GO:0001222)
0.1	0.2	GO:0008311	double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0	0.3	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.5	GO:1990405	protein antigen binding(GO:1990405)
0.0	0.5	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	1.6	GO:0005109	frizzled binding(GO:0005109)
0.0	0.3	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.2	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.6	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	0.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	5.7	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0	1.0	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.6	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0002135	CTP binding(GO:0002135)
0.0	0.2	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.2	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.3	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0030362	protein phosphatase type 4 regulator activity(GO:0030362)
0.0	0.5	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.2	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.5	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.5	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.4	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.7	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.6	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.3	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.4	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0	0.6	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.3	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.2	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)

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